Structural basis for the recognition of para-benzoyl-L-phenylalanine by evolved aminoacyl-tRNA synthetases

Angewandte Chemie - International Edition

Volumn 46, Issue 32, 2007, Pages 6073-6075

  Liu, Wenshe ^a   Alfonta, Lital ^a   Mack, Antha V ^a   Schultz, Peter G ^a  

^a SCRIPPS RESEARCH INSTITUTE   (United States)

Author keywords

Amino acids; Enzymes; Hydrophobic interactions; Photo cross linker; Protein structures

Indexed keywords

HYDROPHOBIC INTERACTIONS; PHOTOCROSSLINKERS; PROTEIN STRUCTURES;

AMINO ACIDS; CROSSLINKING; CRYSTAL STRUCTURE; ENZYME ACTIVITY; HYDROGEN BONDS; MOLECULAR INTERACTIONS; POLYPEPTIDES;

AROMATIC COMPOUNDS;

4 BENZOYLPHENYLALANINE; 4-BENZOYLPHENYLALANINE; AMINO ACID TRANSFER RNA LIGASE; BENZOPHENONE DERIVATIVE; DRUG DERIVATIVE; PHENYLALANINE; UNCLASSIFIED DRUG;

ARTICLE; BINDING SITE; CHEMICAL STRUCTURE; CHEMISTRY; DIRECTED MOLECULAR EVOLUTION; GENETICS; MUTAGENESIS; PROTEIN BINDING; X RAY CRYSTALLOGRAPHY;

AMINO ACYL-TRNA SYNTHETASES; BENZOPHENONES; BINDING SITES; CRYSTALLOGRAPHY, X-RAY; DIRECTED MOLECULAR EVOLUTION; MOLECULAR STRUCTURE; MUTAGENESIS; PHENYLALANINE; PROTEIN BINDING;

EID: 34548082508     PISSN: 14337851     EISSN: None     Source Type: Journal    
DOI: 10.1002/anie.200701990     Document Type: Article

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