-
1
-
-
0037079738
-
Severe coagulation factor V deficiency caused by 2 novel frameshift mutations: 2952delT in exon 13 and 5493insG in exon 16 of factor 5 gene
-
Ajzner E, Balogh I, Szabo T, Marosi A, Haramura G, Muszbek L. Severe coagulation factor V deficiency caused by 2 novel frameshift mutations: 2952delT in exon 13 and 5493insG in exon 16 of factor 5 gene. Blood 2002;99:702-705.
-
(2002)
Blood
, vol.99
, pp. 702-705
-
-
Ajzner, E.1
Balogh, I.2
Szabo, T.3
Marosi, A.4
Haramura, G.5
Muszbek, L.6
-
2
-
-
0030940343
-
First trimester repeated abortion is not associated with activated protein C resistance
-
Balasch J, Reverter JC, Fabregues F, Tassies D, Rafel M, Crues M, Vanrell JA, First trimester repeated abortion is not associated with activated protein C resistance. Hum Reprod 1997;12:1094-1097.
-
(1997)
Hum Reprod
, vol.12
, pp. 1094-1097
-
-
Balasch, J.1
Reverter, J.C.2
Fabregues, F.3
Tassies, D.4
Rafel, M.5
Crues, M.6
Vanrell, J.A.7
-
3
-
-
0030860494
-
A factor V genetic component differing from factor VR506Q contributes to the activated protein C resistance phenotype
-
Bernardi F, Faioni EM, Castoldi B. Lunghi B, Castaman G, Sacchi E, Mannucci PM. A factor V genetic component differing from factor VR506Q contributes to the activated protein C resistance phenotype. Blood 1997;90:1552-1557.
-
(1997)
Blood
, vol.90
, pp. 1552-1557
-
-
Bernardi, F.1
Faioni, E.M.2
Castoldi, B.3
Lunghi, B.4
Castaman, G.5
Sacchi, E.6
Mannucci, P.M.7
-
4
-
-
0028314865
-
Mutation in blood coagulation factor V associated with resistance to activated protein C
-
Bettina RM, Koeleman BP, Koster T, Rosendaal FR, Dirven RJ, de Ronde H, van der Velden PA, Reitsma PH. Mutation in blood coagulation factor V associated with resistance to activated protein C. Nature 1994; 369:64-67.
-
(1994)
Nature
, vol.369
, pp. 64-67
-
-
Bettina, R.M.1
Koeleman, B.P.2
Koster, T.3
Rosendaal, F.R.4
Dirven, R.J.5
de Ronde, H.6
van der Velden, P.A.7
Reitsma, P.H.8
-
5
-
-
0031004309
-
Activated protein C resistance can be associated with recurrent fetal loss
-
Brenner B, Mandel H, Lanir N, Younis J, Rothbart H, Ohel G, Blumenfeld Z. Activated protein C resistance can be associated with recurrent fetal loss. Brit J Haem 1997;97:551-554.
-
(1997)
Brit J Haem
, vol.97
, pp. 551-554
-
-
Brenner, B.1
Mandel, H.2
Lanir, N.3
Younis, J.4
Rothbart, H.5
Ohel, G.6
Blumenfeld, Z.7
-
6
-
-
0032520034
-
A novel mutation of Arg 306 of factor V gene in Hong Kong Chinese
-
Chan WP, Lee CK, Kwong YL, Lam CK, Liang R. A novel mutation of Arg 306 of factor V gene in Hong Kong Chinese. Blood 1998;91 1135-1139.
-
(1998)
Blood
, vol.91
, pp. 1135-1139
-
-
Chan, W.P.1
Lee, C.K.2
Kwong, Y.L.3
Lam, C.K.4
Liang, R.5
-
7
-
-
0021691204
-
Coagulation factors V and VIII and ceruloplasmin constitute a family of structurally related proteins
-
Chuch WR, Jernigan RL, Toole J, Hewick RM, Knopf J, Knutson GJ, Nesheim ME, Mann KG. Coagulation factors V and VIII and ceruloplasmin constitute a family of structurally related proteins. Proc Natl Acad Sci 1984;81:6934-6937.
-
(1984)
Proc Natl Acad Sci
, vol.81
, pp. 6934-6937
-
-
Chuch, W.R.1
Jernigan, R.L.2
Toole, J.3
Hewick, R.M.4
Knopf, J.5
Knutson, G.J.6
Nesheim, M.E.7
Mann, K.G.8
-
8
-
-
0018909419
-
Human coagulation factor V purification and thrombin-catalyzed activation
-
Dahlback B. Human coagulation factor V purification and thrombin-catalyzed activation. J Clin Invest 1980;66:583-591.
-
(1980)
J Clin Invest
, vol.66
, pp. 583-591
-
-
Dahlback, B.1
-
9
-
-
0041334192
-
Acquired activated protein C resistance may be a risk factor for recurrent fetal loss
-
Dawood F, Farquharson R, Quenby S, Toh CH. Acquired activated protein C resistance may be a risk factor for recurrent fetal loss. Fertil Steril 2003;80:649-650.
-
(2003)
Fertil Steril
, vol.80
, pp. 649-650
-
-
Dawood, F.1
Farquharson, R.2
Quenby, S.3
Toh, C.H.4
-
10
-
-
0030963627
-
Fetal carriers of the factor V Leiden mutation are prone to miscarriage and placental infarction
-
Dizon-Townson DS, Moline L, Nelson LM, Varner M, Ward K. Fetal carriers of the factor V Leiden mutation are prone to miscarriage and placental infarction. Am J Obstet Gynecol 1997;177:402-405.
-
(1997)
Am J Obstet Gynecol
, vol.177
, pp. 402-405
-
-
Dizon-Townson, D.S.1
Moline, L.2
Nelson, L.M.3
Varner, M.4
Ward, K.5
-
11
-
-
0026658031
-
Cellular and molecular regulation of factor V expression in human megakaryocytes
-
Gewirtz AM, Shapiro C, Shen YM, Boyd R, Colman RW. Cellular and molecular regulation of factor V expression in human megakaryocytes. J Cell Physiol 1992;153:277-287.
-
(1992)
J Cell Physiol
, vol.153
, pp. 277-287
-
-
Gewirtz, A.M.1
Shapiro, C.2
Shen, Y.M.3
Boyd, R.4
Colman, R.W.5
-
13
-
-
0021750055
-
Characterisation of the human factor VIII gene
-
Gitschier J, Wood WI, Goralka TM, Wion KL, Chen EY, Eaton DH, Vehar GA, Capon DJ, Lawn RM. Characterisation of the human factor VIII gene. Nature 1984;312:326-330.
-
(1984)
Nature
, vol.312
, pp. 326-330
-
-
Gitschier, J.1
Wood, W.I.2
Goralka, T.M.3
Wion, K.L.4
Chen, E.Y.5
Eaton, D.H.6
Vehar, G.A.7
Capon, D.J.8
Lawn, R.M.9
-
14
-
-
0037044806
-
Disruption of the endothelial cell protein C receptor gene in mice causes placental thrombosis and early embryonic lethality
-
Gu JM, Crawley JT, Ferrell G, Zhang F, Li W, Esmon NL, Esmon CT. Disruption of the endothelial cell protein C receptor gene in mice causes placental thrombosis and early embryonic lethality. J Biol Chem 2002;277:43335-43343.
-
(2002)
J Biol Chem
, vol.277
, pp. 43335-43343
-
-
Gu, J.M.1
Crawley, J.T.2
Ferrell, G.3
Zhang, F.4
Li, W.5
Esmon, N.L.6
Esmon, C.T.7
-
15
-
-
0008912897
-
-
Jenny R, Pittman D, Toole J, Kriz RW, Aldape RA, Hewick RM, Kaufman RJ. Mann KG. Complete cDNA and derived amino acid sequence of human FV. Proc Natl Acad Sci USA 1987;84:4846-4850.
-
Jenny R, Pittman D, Toole J, Kriz RW, Aldape RA, Hewick RM, Kaufman RJ. Mann KG. Complete cDNA and derived amino acid sequence of human FV. Proc Natl Acad Sci USA 1987;84:4846-4850.
-
-
-
-
16
-
-
34247880422
-
Variations in the thrombomodulin and endothelial protein C receptor genes in couples with recurrent miscarriage
-
Kaare M, Ulander VM, Painter JN, Ahvenainen T, Kaaja R, Aittomaiki K. Variations in the thrombomodulin and endothelial protein C receptor genes in couples with recurrent miscarriage. Hum Reprod 2007;22 864-868.
-
(2007)
Hum Reprod
, vol.22
, pp. 864-868
-
-
Kaare, M.1
Ulander, V.M.2
Painter, J.N.3
Ahvenainen, T.4
Kaaja, R.5
Aittomaiki, K.6
-
17
-
-
0034666743
-
Frequency of polymorphisms in the B-domain of factor V gene in APC-resistant patients
-
Kostka H, Sieger G, Schwarz T, Gehrisch S, Kuhlisch E, Schellong S, Jaross W. Frequency of polymorphisms in the B-domain of factor V gene in APC-resistant patients. Thromb Res 2000;99:539-547.
-
(2000)
Thromb Res
, vol.99
, pp. 539-547
-
-
Kostka, H.1
Sieger, G.2
Schwarz, T.3
Gehrisch, S.4
Kuhlisch, E.5
Schellong, S.6
Jaross, W.7
-
18
-
-
0033531184
-
Increased frequency of genetic thrombophilia in women with complications of pregnancy
-
Kupferminc MJ, Eldor A, Steiman N, Many A, Bar-Am A, Jaffa A. Increased frequency of genetic thrombophilia in women with complications of pregnancy. NEJM 1999;340:9-13.
-
(1999)
NEJM
, vol.340
, pp. 9-13
-
-
Kupferminc, M.J.1
Eldor, A.2
Steiman, N.3
Many, A.4
Bar-Am, A.5
Jaffa, A.6
-
19
-
-
0037394911
-
Procoagulant and anticoagulant mechanisms in human placenta
-
Lanir N, Aharon A, Brenner B. Procoagulant and anticoagulant mechanisms in human placenta. Semin Thromb Hemost 2003;2:175-184.
-
(2003)
Semin Thromb Hemost
, vol.2
, pp. 175-184
-
-
Lanir, N.1
Aharon, A.2
Brenner, B.3
-
20
-
-
33645578365
-
Activated protein C resistance- in absence of factor V Leiden- and pregnancy
-
Lindqvist PG, Svensson P, Dahlback B. Activated protein C resistance- in absence of factor V Leiden- and pregnancy. J Thromb Haemos 2006; 4:361-366.
-
(2006)
J Thromb Haemos
, vol.4
, pp. 361-366
-
-
Lindqvist, P.G.1
Svensson, P.2
Dahlback, B.3
-
21
-
-
0029941850
-
Comparison of activated protein C/ protein S-mediated inactivation of human factor VIII and factor V
-
Lu D, Kalfatis M, Mann KG, Long GL. Comparison of activated protein C/ protein S-mediated inactivation of human factor VIII and factor V. Blood 1996;87:4708.
-
(1996)
Blood
, vol.87
, pp. 4708
-
-
Lu, D.1
Kalfatis, M.2
Mann, K.G.3
Long, G.L.4
-
22
-
-
0033972844
-
The factor V R2 allele:rIsk of venous thromboembolism, factor V levels and resistance to activated protein C
-
Luddington R, Jackson A, Pannerselvam S, Brwon K, Baglin T. The factor V R2 allele:rIsk of venous thromboembolism, factor V levels and resistance to activated protein C. Thromb Haemost 2000;83:204-208.
-
(2000)
Thromb Haemost
, vol.83
, pp. 204-208
-
-
Luddington, R.1
Jackson, A.2
Pannerselvam, S.3
Brwon, K.4
Baglin, T.5
-
23
-
-
0031975409
-
A new factor V gene polymorphism (His 1254 Arg) present in subjects of African origin mimics the R2 polymorphism. (His 1299 Arg)
-
Lunghi B, Castoldi E, Mingozzi F, Bernardi F. A new factor V gene polymorphism (His 1254 Arg) present in subjects of African origin mimics the R2 polymorphism. (His 1299 Arg). Blood 1998;91:364-365.
-
(1998)
Blood
, vol.91
, pp. 364-365
-
-
Lunghi, B.1
Castoldi, E.2
Mingozzi, F.3
Bernardi, F.4
-
24
-
-
0024400608
-
Biosynthesis of factor V by normal adult rat hepatocytes
-
Mazzorana M, Cornillou B, Baffet G, Hubert N, Eloy R, Guguen-Guilluozo C. Biosynthesis of factor V by normal adult rat hepatocytes. Thromb Res 1989;54:655-675.
-
(1989)
Thromb Res
, vol.54
, pp. 655-675
-
-
Mazzorana, M.1
Cornillou, B.2
Baffet, G.3
Hubert, N.4
Eloy, R.5
Guguen-Guilluozo, C.6
-
25
-
-
0033868908
-
Do placental lesions reflect thrombophilia state in women with adverse pregnancy outcome?
-
Mousa HA, Alfirevic Z. Do placental lesions reflect thrombophilia state in women with adverse pregnancy outcome? Hum Reprod 2000;8 1830-1833.
-
(2000)
Hum Reprod
, vol.8
, pp. 1830-1833
-
-
Mousa, H.A.1
Alfirevic, Z.2
-
26
-
-
0034995296
-
The factor V HR2 haplotype: Prevalence and association of the A4070G and A6755G polymorphisms
-
Pecheniuk NM, Morris CP, Walsh TP, Marsh NA. The factor V HR2 haplotype: prevalence and association of the A4070G and A6755G polymorphisms. Blood Coagul Fibrinolyis 2001;12:201-206.
-
(2001)
Blood Coagul Fibrinolyis
, vol.12
, pp. 201-206
-
-
Pecheniuk, N.M.1
Morris, C.P.2
Walsh, T.P.3
Marsh, N.A.4
-
27
-
-
0028241866
-
Post-translational requirements for functional factor V and factor VIII secretion in mammalian cells
-
Pittman DD, Tomkinson KN, Kaufman RJ. Post-translational requirements for functional factor V and factor VIII secretion in mammalian cells. J Biol Chem 1994;269:17329.
-
(1994)
J Biol Chem
, vol.269
, pp. 17329
-
-
Pittman, D.D.1
Tomkinson, K.N.2
Kaufman, R.J.3
-
28
-
-
0035017316
-
Factor V Leiden and acquired activated protein C resistance among 1000 women with recurrent miscarriage
-
Rai R, Shlebak A, Cohen H, Backos M, Holmes Z, Marriott K, Regan L. Factor V Leiden and acquired activated protein C resistance among 1000 women with recurrent miscarriage. Hum Reprod 2001;16:961-965.
-
(2001)
Hum Reprod
, vol.16
, pp. 961-965
-
-
Rai, R.1
Shlebak, A.2
Cohen, H.3
Backos, M.4
Holmes, Z.5
Marriott, K.6
Regan, L.7
-
29
-
-
0037443934
-
Thrombophilic disorders and fetal loss: A meta-analysis
-
Rey E, Kahn SR, David M, Shrier I. Thrombophilic disorders and fetal loss: A meta-analysis. Lancet 2003;361:901-908.
-
(2003)
Lancet
, vol.361
, pp. 901-908
-
-
Rey, E.1
Kahn, S.R.2
David, M.3
Shrier, I.4
-
30
-
-
0030832735
-
-
Rosing J, Tans G. Factor V. Int J Biochem Cell Biol 1997;29 1123-1126.
-
Rosing J, Tans G. Factor V. Int J Biochem Cell Biol 1997;29 1123-1126.
-
-
-
-
31
-
-
0036149892
-
Thrombophilia is common in women with idiopathic pregnancy loss and is associated with late pregnancy wastage
-
Sarig G, Younis JS, Hoffman R, Lanir N, Blumenfeld Z, Brenner B. Thrombophilia is common in women with idiopathic pregnancy loss and is associated with late pregnancy wastage. Fertil Steril 2002;77 342-347.
-
(2002)
Fertil Steril
, vol.77
, pp. 342-347
-
-
Sarig, G.1
Younis, J.S.2
Hoffman, R.3
Lanir, N.4
Blumenfeld, Z.5
Brenner, B.6
-
32
-
-
0035205945
-
Investigation of genotype-dependent differences in factor V activity as well as response to activated protein C by application of different methods
-
Siegert G, Kostka H, Kuhlisch E, Swartz T, Schellong SM, Jaross W. Investigation of genotype-dependent differences in factor V activity as well as response to activated protein C by application of different methods. Blood Coagul Fibrinolysis 2001;12:683-690.
-
(2001)
Blood Coagul Fibrinolysis
, vol.12
, pp. 683-690
-
-
Siegert, G.1
Kostka, H.2
Kuhlisch, E.3
Swartz, T.4
Schellong, S.M.5
Jaross, W.6
-
33
-
-
0036547768
-
Placental pathology in early onset pre-eclampsia and intra-uterine growth restriction in women with and without thrombophilia
-
Sikkema JM, Franx A, Bruinse HW, van der Wijk NG, de Valk HW, Nikkels PG. Placental pathology in early onset pre-eclampsia and intra-uterine growth restriction in women with and without thrombophilia. Placenta 2002;4:337-342.
-
(2002)
Placenta
, vol.4
, pp. 337-342
-
-
Sikkema, J.M.1
Franx, A.2
Bruinse, H.W.3
van der Wijk, N.G.4
de Valk, H.W.5
Nikkels, P.G.6
-
34
-
-
34249051898
-
Fetal gene defects precipitate platelet-mediated pregnancy failure in factor V Leiden mothers
-
Sood R, Zogg M, Westrick R, Kerschen G, Yi-he EJ, Girardi G, Salmon J, Coughlin SR, Weiler H. Fetal gene defects precipitate platelet-mediated pregnancy failure in factor V Leiden mothers. J Fxp Med 2007; 204:1049-1056.
-
(2007)
J Fxp Med
, vol.204
, pp. 1049-1056
-
-
Sood, R.1
Zogg, M.2
Westrick, R.3
Kerschen, G.4
Yi-he, E.J.5
Girardi, G.6
Salmon, J.7
Coughlin, S.R.8
Weiler, H.9
-
35
-
-
0037222236
-
A new locus on chromosome 18 that influences normal variation in activated protein C resistance phenotype and factor VIII activity and its relation to thrombosis susceptibility
-
Soria JM, Almasy L, Souto JC, Buil A, Martinez- Snachez E, Mateo J, Borrell M, Stone WH, Lathrop M, Fontcuberta et al. A new locus on chromosome 18 that influences normal variation in activated protein C resistance phenotype and factor VIII activity and its relation to thrombosis susceptibility. Blood 2003;101:163-167.
-
(2003)
Blood
, vol.101
, pp. 163-167
-
-
Soria, J.M.1
Almasy, L.2
Souto, J.C.3
Buil, A.4
Martinez- Snachez, E.5
Mateo, J.6
Borrell, M.7
Stone, W.H.8
Lathrop, M.9
Fontcuberta10
-
36
-
-
0025708282
-
Recurrent miscarriage: Definition and epidemiology
-
Stirrat GM. Recurrent miscarriage: Definition and epidemiology. Lancet 1990;336:673-675.
-
(1990)
Lancet
, vol.336
, pp. 673-675
-
-
Stirrat, G.M.1
-
37
-
-
0033040275
-
A possible role for activated protein C resistance in patients with first and second trimester pregnancy failure
-
Tal J, Schliamser LM, Leibovitz Z, Ohel G, Attias D. A possible role for activated protein C resistance in patients with first and second trimester pregnancy failure. Hum Rep 1999;14:1624-1627.
-
(1999)
Hum Rep
, vol.14
, pp. 1624-1627
-
-
Tal, J.1
Schliamser, L.M.2
Leibovitz, Z.3
Ohel, G.4
Attias, D.5
-
38
-
-
0021715169
-
Molecular cloning of a cDNA encoding human antihaemophilic factor
-
Toole JJ, Knopf JL, Wozney JM, Sultzman LA, Buecker JL, Pittman DD, Kaufman RJ, Brown E, Shoemaker C, Orr EC et al. Molecular cloning of a cDNA encoding human antihaemophilic factor. Nature 1984; 312:342-347.
-
(1984)
Nature
, vol.312
, pp. 342-347
-
-
Toole, J.J.1
Knopf, J.L.2
Wozney, J.M.3
Sultzman, L.A.4
Buecker, J.L.5
Pittman, D.D.6
Kaufman, R.J.7
Brown, E.8
Shoemaker, C.9
Orr, E.C.10
-
39
-
-
0019977242
-
Radioimmunoassay of factor V in human plasma and platelets
-
Tracy PB, Eide LL, Bowie FJW, Mann KG. Radioimmunoassay of factor V in human plasma and platelets. Blood 1982;60:59-63.
-
(1982)
Blood
, vol.60
, pp. 59-63
-
-
Tracy, P.B.1
Eide, L.L.2
Bowie, F.J.W.3
Mann, K.G.4
-
40
-
-
0021677942
-
Structure of human factor VIII
-
Vehar GA, Keyt B, Eaton D, Rodrigues H, O'Brien DP, Rotblat F, Opperman H, Keck R, Wood WI, Harkins RN. Structure of human factor VIII. Nature 1984;312:337-342.
-
(1984)
Nature
, vol.312
, pp. 337-342
-
-
Vehar, G.A.1
Keyt, B.2
Eaton, D.3
Rodrigues, H.4
O'Brien, D.P.5
Rotblat, F.6
Opperman, H.7
Keck, R.8
Wood, W.I.9
Harkins, R.N.10
-
41
-
-
0032520041
-
-
Williamson D, Brown K, Luddington R, Baglin C, Baglin I. FV Cambridge: A new mutation (Arg306Thr) associated with the resistance to activated protein C. Blood 1999;91:1140-1144.
-
Williamson D, Brown K, Luddington R, Baglin C, Baglin I. FV Cambridge: A new mutation (Arg306Thr) associated with the resistance to activated protein C. Blood 1999;91:1140-1144.
-
-
-
-
42
-
-
0021329431
-
Biosynthesis of coagulation factor V by a human hepatocellular carcinoma cell line
-
Wilson DB, Salem HH, Mruk JS, Majerus PW. Biosynthesis of coagulation factor V by a human hepatocellular carcinoma cell line. J Clin Invest 1984;73:654-661.
-
(1984)
J Clin Invest
, vol.73
, pp. 654-661
-
-
Wilson, D.B.1
Salem, H.H.2
Mruk, J.S.3
Majerus, P.W.4
-
43
-
-
0033973640
-
Activated protein C resistance and Factor V Leiden mutation can be associated with first- as well as second-med trimester recurrent pregnancy loss
-
Younis JS, Brenner B, Ohel G, Tal J, Lanir N, Ben-Ami M. Activated protein C resistance and Factor V Leiden mutation can be associated with first- as well as second-med trimester recurrent pregnancy loss. Am J Rep Immunol 2000;43:31-35.
-
(2000)
Am J Rep Immunol
, vol.43
, pp. 31-35
-
-
Younis, J.S.1
Brenner, B.2
Ohel, G.3
Tal, J.4
Lanir, N.5
Ben-Ami, M.6
|