Immunohistochemical expression of platelet growth factor and vascular endothelial growth factor in patients with melanoma with and without redness (Brenner sign)

Archives of Dermatology

Volumn 143, Issue 8, 2007, Pages 1001-1004

  Mashiah, Jacob ^a   Wohl, Yonit ^a   Barnea, Yoav ^a   Schneebaum, Shlomo ^a   Gat, Andrea ^a   Misonzhnik Bedny, Faina ^a   Brenner, Sarah ^a,b  

^a TEL AVIV UNIVERSITY   (Israel)

^b TEL AVIV SOURASKY MEDICAL CENTER   (Israel)

Author keywords

[No Author keywords available]

Indexed keywords

PLATELET DERIVED GROWTH FACTOR; VASCULOTROPIN;

ADULT; AGED; ARTICLE; BRENNER TUMOR; CLINICAL ARTICLE; CORRELATION ANALYSIS; DISEASE ASSOCIATION; ERYTHEMA; FEMALE; HUMAN; HUMAN TISSUE; IMMUNOHISTOCHEMISTRY; IMMUNOREACTIVITY; MALE; MELANOMA; PATHOGENESIS; PRIORITY JOURNAL; PROTEIN EXPRESSION; SKIN BIOPSY; TUMOR BIOPSY;

ADULT; AGED; AGED, 80 AND OVER; CASE-CONTROL STUDIES; ERYTHEMA; FEMALE; HUMANS; MALE; MELANOMA; MIDDLE AGED; PLATELET-DERIVED GROWTH FACTOR; SKIN NEOPLASMS; VASCULAR ENDOTHELIAL GROWTH FACTOR A;

EID: 34548063555     PISSN: 0003987X     EISSN: 0003987X     Source Type: Journal    
DOI: 10.1001/archderm.143.8.1001     Document Type: Article

References (16)

1. Langley RGB, Barnhill RL, Mihm MC Jr, Fitzpatrick TB, Sober AJ. Neoplasms: cutaneous melanoma. In: Freedberg IM, Eisen AZ, Wolff K, et al, eds. Fitzpatrick's Dermatology in General Medicine. Vol 2. 6th ed. New York, NY: McGraw-Hill Co; 2003:917-955.
2. Lázár-Molnár E, Hegyesi H, Toth S, Falus A. Autocrine and paracrine regulation by cytokines and growth factors in melanoma. Cytokine. 2000;12(6):547-554.
3. Redondo P, Sanchez-Carpintero I, Bauza A, Idoate M, Solano T, Mihm MC Jr. Immunologic escape and angiogenesis in human malignant melanoma. J Am Acad Dermatol. 2003;49(2):255-263.
4. Pierard GE, Pierard-Franchimont C, Lapiere CM. Proliferation and hyperplasia of vascular endothelium in human skin. Am J Dermatopathol. 1985;7(5):477-488.
5. Hanahan D, Folkman J. Patterns and emerging mechanisms of the angiogenic switch during tumorigenesis. Cell. 1996;86(3):353-364.
6. Brenner S, Wolf R. The "red face" - a warning sign of malignant melanoma [letter]? Acta Derm Venereol. 1992;72(6):464.
7. Tamir E, Brenner S. A case of "red face": a clue to early detection of malignant melanoma Skinmed. 2003;2(5):272.
8. Mashiah J, Barnea Y, Wohl Y, Brenner S. Redness, a possible signpost for malignant melanoma [letter]. J Eur Acad Dermatol Venereol. 2005;19(4):514-515.
9. Srivastava A, Ralhan R, Kaur J. Angiogenesis in cutaneous melanoma: pathogenesis and clinical implications. Microsc Res Tech. 2003;60(2):208-224.
10. Heldin CH, Ostman A, Ronnstrand L. Signal transduction via platelet-derived growth factor receptors. Biochim Biophys Acta. 1998;1378(1):F79-F113.
11. Pietras K, Sjoblom T, Rubin K, Heldin CH, Ostman A. PDGF receptors as cancer drug targets. Cancer Cell. 2003;3(5):439-443.
12. Furuhashi M, Sjoblom T, Abramsson A, et al. Platelet-derived growth factor production by B16 melanoma cells leads to increased pericyte abundance in tumors and an associated increase in tumor growth rate. Cancer Res. 2004;64(8):2725-2733.
13. Hellström M, Kalen M, Lindahl P, Abramsson A, Betsholtz C. Role of PDGF-B and PDGFR-beta in recruitment of vascular smooth muscle cells and pericytes during embryonic blood vessel formation in the mouse. Development. 1999;126(14):3047-3055.
14. Claffey KP, Brown LF, del Aguila LF, et al. Expression of vascular permeability factor/vascular endothelial growth factor by melanoma cells increases tumor growth, angiogenesis, and experimental metastasis. Cancer Res. 1996;56(1):172-181.
15. Govindarajan B, Bai X, Cohen C, et al. Malignant transformation of melanocytes to melanoma by constitutive activation of mitogen-activated protein kinase kinase (MAPKK) signaling [published online ahead of print January 3, 2003]. J Biol Chem. 2003;278(11):9790-9795.
16. Cohen C, Zavala-Pompa A, Sequeira JH, et al. Mitogen-actived protein kinase activation is an early event in melanoma progression. Clin Cancer Res. 2002;8(12):3728-3733.