Inoculation of Chlamydia pneumoniae or Chlamydia trachomatis with ligands that inhibit attachment to host cells reduces infectivity in the mouse model of lung infection: implication for anti-adhesive therapy

Microbes and Infection

Volumn 9, Issue 9, 2007, Pages 1139-1141

  Kuo, Cho Chou ^a   Lee, Amy ^a   Jiang, Shinn Jong ^a   Yaraei, Kambiz ^a   Campbell, Lee Ann ^a  

^a UNIVERSITY OF WASHINGTON   (United States)

Author keywords

Anti adhesive; Chlamydia; Glycan; Mannose oligosaccharide

Indexed keywords

GLYCAN; MANNOSE; OLIGOSACCHARIDE;

ANIMAL EXPERIMENT; ANIMAL TISSUE; ARTICLE; BACTERIAL INFECTION; BACTERIAL MEMBRANE; BACTERIUM ADHERENCE; CHLAMYDIA TRACHOMATIS; CHLAMYDOPHILA PNEUMONIAE; CONTROLLED STUDY; HOST CELL; INFECTION PREVENTION; INOCULATION; LIGAND BINDING; LUNG INFECTION; MOUSE; NONHUMAN; PRIORITY JOURNAL; SWISS WEBSTER MOUSE;

ACRYLIC RESINS; ANIMALS; ATTACHMENT SITES, MICROBIOLOGICAL; BACTERIAL ADHESION; CHLAMYDIA INFECTIONS; CHLAMYDIA TRACHOMATIS; CHLAMYDOPHILA PNEUMONIAE; LIGANDS; LUNG; LUNG DISEASES; MANNANS; MANNOSE; MICE; MODELS, ANIMAL; OLIGOSACCHARIDES; PNEUMONIA, BACTERIAL; RECEPTOR, IGF TYPE 2;

ANIMALIA; CHLAMYDIA; CHLAMYDIA TRACHOMATIS; CHLAMYDOPHILA PNEUMONIAE;

EID: 34548011920     PISSN: 12864579     EISSN: 1769714X     Source Type: Journal    
DOI: 10.1016/j.micinf.2007.04.014     Document Type: Article

References (12)

1. Wyrick P.P., Chang J., Davis C.H., Knight S.T., Royal M.D., Maslow A.S., and Bagnell C.R. Entry of genital Chlamydia trachomatis into polarized human epithelial cells. Infect. Immun. 57 (1980) 2378-2389
2. Zhang J.P., and Stephens R.S. Mechanism of C. trachomatis attachment to eukaryotic host cells. Cell 69 (1992) 861-869
3. Su H., Watkins N.G., Zhang Y.X., and Caldwell H.D. Chlamydia trachomatis host cell interactions: role of the chlamydial major outer membrane protein as an adhesin. Infect. Immun. 58 (1990) 1017-1025
4. Raulston J.E., Davis C.H., Schmiel D.H., Morgan M.W., and Wyrick P.B. Molecular characterization and host membrane association of a Chlamydia trachomatis protein related to the hsp70 family of proteins. J. Biol. Chem. 268 (1993) 23139-23147
5. Kuo C.-C., Takahashi N., Swanson A.F., Ozeki Y., and Hakomori S.I. An N-linked high-mannose type oligosaccharide, expressed at the major outer membrane protein of Chlamydia trachomatis, mediates attachment and infectivity of the microorganism to HeLa cells. J. Clin. Invest. 98 (1996) 2813-2818
6. Kuo C.-C., Lee A., and Campbell L.A. Cleavage of the N-linked oligosaccharide from the surface of Chlamydia species affects attachment and infectivity of the organisms in human epithelial and endothelial cells. Infect. Immun. 72 (2004) 6699-6701
7. Puolakkainen M., Kuo C.-C., and Campbell L.A. Mannose 6-phosphate inhibits growth of Chlamydia pneumoniae in human arterial endothelial cells. Infect. Immun. 78 (2005) 4620-4625
8. Kuo C.-C., Puolakkainen M., Lin T.-M., Witte M., and Campbell L.A. Mannose-receptor positive and negative mouse macrophages differ in their susceptibility to infection by Chlamydia species. Microb. Pathogen. 32 (2002) 43-48
9. Campbell L.A., Lee A., and Kuo C.-C. Cleavage of the N-linked oligosaccharide from the surfaces of Chlamydia species affects infectivity in the mouse model of lung infection. Infect. Immun. 74 (2006) 3027-3029
10. Kuo C.-C., and Chen W.-J. A mouse model of Chlamydia trachomatis pneumonitis. J. Infect. Dis. 141 (1980) 198-202
11. Yang Z.-P., Kuo C.-C., and Grayston J.T. A mouse model of Chlamydia pneumoniae strain TWAR pneumonitis. Infect. Immun. 61 (1993) 2037-2040
12. Moazed T.C., Kuo C.-C., Grayston J.T., and Campbell L.A. Murine models of Chlamydia pneumoniae infection and atherosclerosis. J. Infect. Dis. 175 (1996) 883-890