Acute promyelocytic leukemia in patients aged 70 years and over - A single center experience of unselected patients [10]

Leukemia and Lymphoma

Volumn 48, Issue 8, 2007, Pages 1654-1658

  Disperati, Patricia ^a   Minden, Mark D ^a   Gupta, Vikas ^a   Schimmer, Aaron D ^a   Schuh, Andre C ^a   Yee, Karen W L ^a   Kamel Reid, Suzanne ^a   Chang, Hong ^a   Xu, Wei ^a   Brandwein, Joseph M ^a  

^a PRINCESS MARGARET HOSPITAL   (Canada)

Author keywords

[No Author keywords available]

Indexed keywords

AMSACRINE; CYTARABINE; DAUNORUBICIN; DEXAMETHASONE; MERCAPTOPURINE; METHOTREXATE; PROMYELOCYTIC LEUKEMIA PROTEIN; RADIOACTIVE IODINE; RETINOIC ACID; RETINOIC ACID RECEPTOR ALPHA;

AGED; CANADA; CANDIDEMIA; CLINICAL ARTICLE; COMPLETE HEART BLOCK; CONGESTIVE HEART FAILURE; CONTINUOUS INFUSION; CONTROLLED STUDY; DRUG SUBSTITUTION; ENTEROCOLITIS; FEBRILE NEUTROPENIA; FEMALE; GERIATRIC PATIENT; HEART DISEASE; HEART LEFT VENTRICLE EJECTION FRACTION; HUMAN; HYPERTHYROIDISM; LETTER; MALE; MONOTHERAPY; OVERALL SURVIVAL; PATIENT SELECTION; PNEUMONIA; PRIORITY JOURNAL; PROMYELOCYTIC LEUKEMIA; RETINOIC ACID SYNDROME; RETROSPECTIVE STUDY; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION; SIDE EFFECT;

AGED; AGED, 80 AND OVER; ANTINEOPLASTIC COMBINED CHEMOTHERAPY PROTOCOLS; FEMALE; HUMANS; LEUKEMIA, PROMYELOCYTIC, ACUTE; MALE; PROGNOSIS; RETROSPECTIVE STUDIES; SURVIVAL RATE;

EID: 34547993586     PISSN: 10428194     EISSN: 10292403     Source Type: Journal    
DOI: 10.1080/10428190701472005     Document Type: Letter

References (14)

1. Buchner, T., Berdel, W. E., Wörmann, B., Schoch, C., Haferlach, T. and Schnittger, S. (2005) Treatment of older patients with AML. Crit Rev Oncol Hematol, 56, pp. 247-259.
2. Lowenberg, B., Zittoun, R., Kerhofs, H., Jehn, U., Abels, J. and Debusscher, L. (1989) On the value of intensive remission-induction chemotherapy in elderly patients of 65+ years with acute myeloid leukemia: A randomized phase III study of the European Organization for Research and Treatment of Cancer Leukemia Group. J Clin Oncol, 7, pp. 1268-1274.
3. Tilly, H., Castaigne, S., Bordessoule, D., Casassus, P., Prise, P Y Le and Tertian, G. (1990) Low-dose cytarabine versus intensive chemotherapy in the treatment of acute nonlymphocytic leukemia in the elderly. J Clin Oncol, 8, pp. 272-279.
4. Tallman, M. S. and Nabhan, C. (2002) Management of acute promyelocytic leukemia. Curr Oncol Rep, 4, pp. 381-389.
5. Fenaux, P., Chevret, S. and de Botton, S. (2003) Treatment of older adults with acute promyelocytic leukaemia. Best Pract Res Clin Haematol, 16, pp. 495-501.
6. Sanz, M. A., Vellenga, E., Rayón, C., Díaz-Mediavilla, J., Rivas, C. and Amutio, E. (2004) All-trans retinoic acid and anthracycline monochemotherapy for the treatment of elderly patients with acute promyelocytic leukemia. Blood, 104, pp. 3490-3493.
7. Latagliata, R., Avvisati, G., Coco, F Lo, Petti, M. C., Diverio, D. and Spadea, A. (1997) The role of all-trans-retinoic acid (ATRA) treatment in newly-diagnosed acute promyelocytic leukemia patients aged >60 years. Ann Oncol, 8, pp. 1273-1275.
8. Mandelli, F., Latagliata, R., Avvisati, G., Fazi, P., Rodeghiero, F. and Leoni, F. (2003) Treatment of elderly patients (>or=60 years) with newly diagnosed acute promyelocytic leukemia. Results of the Italian multicenter group GIMEMA with ATRA and idarubicin (AIDA) protocols. Leukemia, 17, pp. 1085-1090.
9. Ades, L., Chevret, S., De Botton, S., Thomas, X., Dombret, H. and Beve, B. (2005) Outcome of acute promyelocytic leukemia treated with all trans retinoic acid and chemotherapy in elderly patients: The European group experience. Leukemia, 19, pp. 230-233.
10. Frankel, S. R., Eardley, A., Lauwers, G., Weiss, M. and Warrell Jr, R. P. (1992) The "retinoic acid syndrome" in acute promyelocytic leukemia. Ann Intern Med, 117, pp. 292-296.
11. Ades, L., Raffoux, E., Chevret, S., de Botton, S., Guerci, A. and Pigneux, A. (2004) Is AraC required in the treatment of newly diagnosed APL? Results of a randomized trial (APL 2000). Blood, 104, p. 115a.
12. Grimwade, D., Walker, H., Oliver, F., Wheatley, K., Harrison, C. and Harrison, G. (1998) The importance of diagnostic cytogenetics on outcome in AML: Analysis of 1,612 patients entered into the MRC AML 10 trial. The Medical Research Council Adult and Children's Leukaemia Working Parties. Blood, 92, pp. 2322-2333.
13. Sanz, B. M., Carli, P. M., Maloisel, F., Thomas, X. and Detourmignies, L. (2003) Therapy-related acute promyelocytic leukemia. J Clin Oncol, 21, pp. 2123-2137.
14. Gupta, V., Chun, K., Yi, Q. -L., Minden, M., Schuh, A. and Wells, R. (2005) Disease biology rather than age is the most important determinant of survival of patients > or = 60 years with acute myeloid leukemia treated with uniform intensive therapy. Cancer, 3, pp. 2082-2090.