Preparation and characterization of release behavior for hydrophilic dung loaded alginate nanohydrogels

2007 NSTI Nanotechnology Conference and Trade Show - NSTI Nanotech 2007, Technical Proceedings

Volumn 4, Issue , 2007, Pages 250-253

  Lee, S M ^a   Lee, H Y ^a   Kim, Y M ^a   Kim, M K ^a   Sohn, S O ^a   Ghim, H D ^a  

^a Kyungpook National University   (South Korea)

Author keywords

Alginate nanohydrogels; Controlled release; Hydrophilic drug; Reverse emulsification diffusion method

Indexed keywords

BIOCOMPATIBILITY; BIODEGRADATION; HYDROGELS; NANOPARTICLES;

ALGINATE NANOHYDROGELS; HYDROPHILIC DRUG; REVERSE EMULSIFICATION-DIFFUSION METHOD;

CONTROLLED DRUG DELIVERY;

EID: 34547992352     PISSN: None     EISSN: None     Source Type: Conference Proceeding    
DOI: None     Document Type: Conference Paper

References (11)

1. P.D. Scholes, A.G.A. Coombes, L. Illum, S.S. Davis, M. Vert and M.C Davies, "The preparation of sub-500 nm poly(lactide-co-glycolide) microspheres for site-specific drug delivery", J. Control. Rel., 25, 145-153, 1993.
2. S. Mawson, K.P. Johnston, J.R. Combes and J.M. DeSimone, "Formation of poly(1,1,2,2-tetrahydroperfluorodecyl acrylate) submicron fibers and particles from supercritical carbon dioxide solutions", Macromolecules, 28, 3182-3191, 1994.
3. J.C. Leroux, E. Allemann, E. Doelker and R. Gurnay, "New approach for the preparation of nanoparticles by an emulsification-diffusion method", Eur. J. Pharm. Biopharm., 41, 14-18, 1995.
4. Skjak-Braek G., "Alginates: biosyntheses and some structure-function relationships relevant to biomedical and bioechnological applications", Biochemistry of Plant Polysaccharides, 20, 27-33, 1992.
5. Sugawara S., Imai T. and Otagiri M., "The controlled release of prednisolone using alginate gel". Pharmaceutical Research, 11, 272-277, 1994.
6. Wan L.S.C., Lim L.Y., and Soh B.L., "Relationship between swelling and drug release in a hydrophilic matrix", Drug Development and Industrial Pharmacy, 19, 1201-1210, 1994.
7. Gray C.J. and Dowsett J., "Retention of insulin in alginate gel beads", Biotechnology and Bioengineering, 31, 607-612, 1998.
8. Shiraishi S., Arahira M., Imai T. and Otagiri M., "Enhancement of dissolution rates of several drugs by low-molecular chitosan and alginate", Chemical Pharmaceutical Bulletin, 38, 185-187, 1990.
9. Mumper R.J., HoFFman A.S., Puolakkinen P.A., Bouchard L.S. and Gombotz W.R.,"Calcium-alginate beads for the oral delivery of transforming growth factor-b 1 (TGF-β1): stabilization of TGF-β1 by the addition of polyacrylic acid within acid-treated beads", Journal of Controlled Release, 30, 241-251, 1994.
10. Bernkop-Schnurch A. and Krajicek M.E., "Mucoadhesive polymers as platforms for peroral peptide delivery and absorption: synthesis and evaluation of different chitosan-EDTA conjugates", J. Control. Rel., 50, 215-223, 1998.
11. E.J.A.M. Schchlicher, N. S. Postma, J. Zuidema, H. Talsma and W.E. Hennink, Int. J. Pharm., 153, 235, 1997.