메뉴 건너뛰기




Volumn 98, Issue 3, 2007, Pages 550-555

Hypocholesterolaemic effects of plant sterol analogues are independent of ABCG5 and ABCG8 transporter expressions in hamsters

Author keywords

ABCG5; ABCG8; Cholesterol; Hamsters; Plant sterols

Indexed keywords

ASCORBIC ACID; CASEIN; CHOLESTEROL; CHOLESTEROL TRANSPORTER ABCG5; CHOLESTEROL TRANSPORTER ABCG8; FISH OIL; HIGH DENSITY LIPOPROTEIN CHOLESTEROL; MESSENGER RNA; PHYTOSTEROL; STANOL; STANOL ESTER; STARCH; STEROL DERIVATIVE; STEROL ESTER; SUCROSE; UNCLASSIFIED DRUG;

EID: 34547987745     PISSN: 00071145     EISSN: 14752662     Source Type: Journal    
DOI: 10.1017/S0007114507721517     Document Type: Article
Times cited : (21)

References (37)
  • 1
    • 33947253738 scopus 로고
    • Reduction of blood cholesterol in man
    • Pollak OJ (1953) Reduction of blood cholesterol in man. Circulation 7, 702-706.
    • (1953) Circulation , vol.7 , pp. 702-706
    • Pollak, O.J.1
  • 2
    • 0021010872 scopus 로고
    • Absorption and metabolism of dietary cholesterol
    • Grundy SM (1983) Absorption and metabolism of dietary cholesterol. Annu Rev Nutr 3, 71-96.
    • (1983) Annu Rev Nutr , vol.3 , pp. 71-96
    • Grundy, S.M.1
  • 3
    • 0033049497 scopus 로고    scopus 로고
    • Cholesterol-lowering efficacy of a sitostanol-containing phytosterol mixture with a prudent diet in hyperlipidemic men
    • Jones PJ, Ntanios FY, Raeini-Sarjaz M & Vanstone CA (1999) Cholesterol-lowering efficacy of a sitostanol-containing phytosterol mixture with a prudent diet in hyperlipidemic men. Am J Clin Nutr 69, 1144-1150.
    • (1999) Am J Clin Nutr , vol.69 , pp. 1144-1150
    • Jones, P.J.1    Ntanios, F.Y.2    Raeini-Sarjaz, M.3    Vanstone, C.A.4
  • 4
    • 0033804429 scopus 로고    scopus 로고
    • Comparison of the effects of plant sterol ester and plant stanol ester-enriched margarines in lowering serum cholesterol concentrations in hypercholesterolaemic subjects on a low-fat diet
    • Hallikainen MA, Sarkkinen ES, Gylling H, Erkkila AT & Uusitupa MI (2000) Comparison of the effects of plant sterol ester and plant stanol ester-enriched margarines in lowering serum cholesterol concentrations in hypercholesterolaemic subjects on a low-fat diet. Eur J Clin Nutr 54, 715-725.
    • (2000) Eur J Clin Nutr , vol.54 , pp. 715-725
    • Hallikainen, M.A.1    Sarkkinen, E.S.2    Gylling, H.3    Erkkila, A.T.4    Uusitupa, M.I.5
  • 5
    • 0036895750 scopus 로고    scopus 로고
    • Unesterified plant sterols and stanols lower LDL-cholesterol concentrations equivalently in hypercholesterolemic persons
    • Vanstone CA, Raeini-Sarjaz M, Parsons WE & Jones PJ (2002) Unesterified plant sterols and stanols lower LDL-cholesterol concentrations equivalently in hypercholesterolemic persons. Am J Clin Nutr 76 1272-1278.
    • (2002) Am J Clin Nutr , vol.76 , pp. 1272-1278
    • Vanstone, C.A.1    Raeini-Sarjaz, M.2    Parsons, W.E.3    Jones, P.J.4
  • 7
    • 0037381181 scopus 로고    scopus 로고
    • Decrease in plasma low-density lipoprotein cholesterol, apolipoprotein B, cholesteryl ester transfer protein, and oxidized low-density lipoprotein by plant stanol ester-containing spread: A randomized, placebo-controlled trial
    • Homma Y, Ikeda I, Ishikawa, T, Tateno M, Sugano M & Nakamura H (2003) Decrease in plasma low-density lipoprotein cholesterol, apolipoprotein B, cholesteryl ester transfer protein, and oxidized low-density lipoprotein by plant stanol ester-containing spread: A randomized, placebo-controlled trial. Nutrition 19, 369-374.
    • (2003) Nutrition , vol.19 , pp. 369-374
    • Homma, Y.1    Ikeda, I.2    Ishikawa, T.3    Tateno, M.4    Sugano, M.5    Nakamura, H.6
  • 8
    • 33646594325 scopus 로고    scopus 로고
    • Effects on plasma lipids when plant sterol enriched fat spread or carbohydrate provide replacement energy for saturated fatty acids
    • Skeaff CM, Thoma C, Chisholm A, Mann J & Williams S (2004) Effects on plasma lipids when plant sterol enriched fat spread or carbohydrate provide replacement energy for saturated fatty acids. Asia Pac J Clin Nutr 13, S80.
    • (2004) Asia Pac J Clin Nutr , vol.13
    • Skeaff, C.M.1    Thoma, C.2    Chisholm, A.3    Mann, J.4    Williams, S.5
  • 9
    • 2942547080 scopus 로고    scopus 로고
    • Effect of free plant sterols in low-fat milk on serum lipid profile in hypercholesterolemic subjects
    • Thomsen AB, Hansen HB, Christiansen C, Green H & Berger A (2004) Effect of free plant sterols in low-fat milk on serum lipid profile in hypercholesterolemic subjects. Eur J Clin Nutr 58, 860-870.
    • (2004) Eur J Clin Nutr , vol.58 , pp. 860-870
    • Thomsen, A.B.1    Hansen, H.B.2    Christiansen, C.3    Green, H.4    Berger, A.5
  • 10
    • 0035957037 scopus 로고    scopus 로고
    • AHA Science Advisory. Stanol/ sterol ester-containing foods and blood cholesterol levels. A statement for healthcare professionals from the Nutrition Committee of the Council on Nutrition, Physical Activity, and Metabolism of the American Heart Association
    • Lichtenstein AH & Deckelbaum RJ (2001) AHA Science Advisory. Stanol/ sterol ester-containing foods and blood cholesterol levels. A statement for healthcare professionals from the Nutrition Committee of the Council on Nutrition, Physical Activity, and Metabolism of the American Heart Association. Circulation 103, 1177-1179.
    • (2001) Circulation , vol.103 , pp. 1177-1179
    • Lichtenstein, A.H.1    Deckelbaum, R.J.2
  • 11
    • 0036403449 scopus 로고    scopus 로고
    • Phytosterols in human nutrition
    • Ostlund RE Jr, (2002) Phytosterols in human nutrition. Annu Rev Nutr 22, 533-549.
    • (2002) Annu Rev Nutr , vol.22 , pp. 533-549
    • Ostlund Jr, R.E.1
  • 12
    • 0035155436 scopus 로고    scopus 로고
    • Effects of a novel hydrophilic phytostanol analog on plasma lipid concentrations in gerbils
    • Wasan KM, Najafi S, Peteherych KD & Pritchard PH (2001) Effects of a novel hydrophilic phytostanol analog on plasma lipid concentrations in gerbils. J Pharm Sci 90, 1795-1799.
    • (2001) J Pharm Sci , vol.90 , pp. 1795-1799
    • Wasan, K.M.1    Najafi, S.2    Peteherych, K.D.3    Pritchard, P.H.4
  • 13
    • 0035735017 scopus 로고    scopus 로고
    • Assessing plasma lipid levels, body weight, and hepatic and renal toxicity following chronic oral administration of a water soluble phytostanol compound, FM-VP4, to gerbils
    • Wasan KM, Najafi S, Wong J, Kwong M & Pritchard PH (2001) Assessing plasma lipid levels, body weight, and hepatic and renal toxicity following chronic oral administration of a water soluble phytostanol compound, FM-VP4, to gerbils. J Pharm Pharm Sci 4, 228-234.
    • (2001) J Pharm Pharm Sci , vol.4 , pp. 228-234
    • Wasan, K.M.1    Najafi, S.2    Wong, J.3    Kwong, M.4    Pritchard, P.H.5
  • 14
    • 0038413736 scopus 로고    scopus 로고
    • Disodium ascorbyl phytostanyl phosphate reduces plasma cholesterol concentrations and atherosclerotic lesion formation in apolipoprotein E-deficient mice
    • Lukic T, Wasan KM, Zamfir D, Moghadasian MH & Pritchard PH (2003) Disodium ascorbyl phytostanyl phosphate reduces plasma cholesterol concentrations and atherosclerotic lesion formation in apolipoprotein E-deficient mice. Metabolism 52, 425-431.
    • (2003) Metabolism , vol.52 , pp. 425-431
    • Lukic, T.1    Wasan, K.M.2    Zamfir, D.3    Moghadasian, M.H.4    Pritchard, P.H.5
  • 15
    • 0022922341 scopus 로고
    • Investigation of the role of micellar phospholipid in the preferential uptake of cholesterol over sitosterol by dispersed rat jejunal villus cells
    • Child P & Kuksis A (1986) Investigation of the role of micellar phospholipid in the preferential uptake of cholesterol over sitosterol by dispersed rat jejunal villus cells. Biochem Cell Biol 64, 847-853.
    • (1986) Biochem Cell Biol , vol.64 , pp. 847-853
    • Child, P.1    Kuksis, A.2
  • 16
  • 17
    • 0034794773 scopus 로고    scopus 로고
    • Injected phytosterols/ stanols suppress plasma cholesterol levels in hamsters
    • Vanstone CA, Raeini-Sarjaz M & Jones PJ (2001) Injected phytosterols/ stanols suppress plasma cholesterol levels in hamsters. J Nutr Biochem 12, 565-574.
    • (2001) J Nutr Biochem , vol.12 , pp. 565-574
    • Vanstone, C.A.1    Raeini-Sarjaz, M.2    Jones, P.J.3
  • 19
    • 0035158733 scopus 로고    scopus 로고
    • Lee MH, Lu & Hazard S, Yu H. et al. (2001) Identification of a gene, ABCG5, important in the regulation of dietary cholesterol absorption. Nat Genet 27, 79-83.
    • Lee MH, Lu & Hazard S, Yu H. et al. (2001) Identification of a gene, ABCG5, important in the regulation of dietary cholesterol absorption. Nat Genet 27, 79-83.
  • 22
    • 0036733630 scopus 로고    scopus 로고
    • Overexpression of ABCG5 and ABCG8 promotes biliary cholesterol secretion and reduces fractional absorption of dietary cholesterol
    • Yu L, Li-Hawkins J, Hammer RE, Berge KE, Horton JD, Cohen JC & Hobbs HH (2002) Overexpression of ABCG5 and ABCG8 promotes biliary cholesterol secretion and reduces fractional absorption of dietary cholesterol. J Clin Invest 110, 671-680.
    • (2002) J Clin Invest , vol.110 , pp. 671-680
    • Yu, L.1    Li-Hawkins, J.2    Hammer, R.E.3    Berge, K.E.4    Horton, J.D.5    Cohen, J.C.6    Hobbs, H.H.7
  • 23
    • 10044226295 scopus 로고    scopus 로고
    • Stanol esters decrease plasma cholesterol independently of intestinal ABC sterol transporters and Niemann-Pick C1-like 1 protein gene expression
    • Field FJ, Born E & Mathur SN (2004) Stanol esters decrease plasma cholesterol independently of intestinal ABC sterol transporters and Niemann-Pick C1-like 1 protein gene expression. J Lipid Res 45 2252-2259.
    • (2004) J Lipid Res , vol.45 , pp. 2252-2259
    • Field, F.J.1    Born, E.2    Mathur, S.N.3
  • 25
    • 33746660272 scopus 로고    scopus 로고
    • Reduction of cholesterol absorption by dietary plant sterols and stanols in mice is independent of the Abcg5/8 transporter
    • Plosch T, Kruit JK, Bloks VW, Huijkman NC, Havinga R, Duchateau GS, Lin Y & Kuipers F (2006) Reduction of cholesterol absorption by dietary plant sterols and stanols in mice is independent of the Abcg5/8 transporter. J Nutr 136, 2135-2140.
    • (2006) J Nutr , vol.136 , pp. 2135-2140
    • Plosch, T.1    Kruit, J.K.2    Bloks, V.W.3    Huijkman, N.C.4    Havinga, R.5    Duchateau, G.S.6    Lin, Y.7    Kuipers, F.8
  • 26
    • 0027243366 scopus 로고
    • Animal models of human lipid metabolism
    • Suckling KE & Jackson B (1993) Animal models of human lipid metabolism. Prog Lipid Res 32, 1-24.
    • (1993) Prog Lipid Res , vol.32 , pp. 1-24
    • Suckling, K.E.1    Jackson, B.2
  • 27
    • 0030898403 scopus 로고    scopus 로고
    • Design criteria for studies examining individual fatty acid effects on cardiovascular disease risk factors: Human and animal studies
    • Kris-Etherton PM & Dietschy J (1997) Design criteria for studies examining individual fatty acid effects on cardiovascular disease risk factors: Human and animal studies. Am J Clin Nutr 65, 1590S-1596S.
    • (1997) Am J Clin Nutr , vol.65
    • Kris-Etherton, P.M.1    Dietschy, J.2
  • 28
    • 0020004724 scopus 로고
    • 2+ precipitation procedure for quantitation of high-density-lipoprotein cholesterol
    • 2+ precipitation procedure for quantitation of high-density-lipoprotein cholesterol. Clin Chem 28, 1379-1388.
    • (1982) Clin Chem , vol.28 , pp. 1379-1388
    • Warnick, G.R.1    Benderson, J.2    Albers, J.J.3
  • 29
    • 0015348189 scopus 로고
    • Estimation of the concentration of low-density lipoprotein cholesterol in plasma, without use of the preparative ultracentrifuge
    • Friedewald WT, Levy RI & Fredrickson DS (1972) Estimation of the concentration of low-density lipoprotein cholesterol in plasma, without use of the preparative ultracentrifuge. Clin Chem 18, 499-502.
    • (1972) Clin Chem , vol.18 , pp. 499-502
    • Friedewald, W.T.1    Levy, R.I.2    Fredrickson, D.S.3
  • 30
    • 0032920384 scopus 로고    scopus 로고
    • Dietary sitostanol reciprocally influences cholesterol absorption and biosynthesis in hamsters and rabbits
    • Ntanios FY & Jones PJ (1999) Dietary sitostanol reciprocally influences cholesterol absorption and biosynthesis in hamsters and rabbits. Atherosclerosis 143, 341-351.
    • (1999) Atherosclerosis , vol.143 , pp. 341-351
    • Ntanios, F.Y.1    Jones, P.J.2
  • 32
    • 0037166261 scopus 로고    scopus 로고
    • Regulation of ATP-binding cassette sterol transporters ABCG5 and ABCG8 by the liver X receptors α and β
    • Repa JJ, Berge KE, Pomajzl C, Richardson JA, Hobbs H & Mangelsdorf DJ (2002) Regulation of ATP-binding cassette sterol transporters ABCG5 and ABCG8 by the liver X receptors α and β. J Biol Chem 277, 18793-18800.
    • (2002) J Biol Chem , vol.277 , pp. 18793-18800
    • Repa, J.J.1    Berge, K.E.2    Pomajzl, C.3    Richardson, J.A.4    Hobbs, H.5    Mangelsdorf, D.J.6
  • 33
    • 0036845043 scopus 로고    scopus 로고
    • Inhibition of cholesterol absorption by SCH 58053 in the mouse is not mediated via changes in the expression of mRNA for ABCA1, ABCG5, or ABCG8 in the enterocyte
    • Repa JJ, Dietschy JM & Turley SD (2002) Inhibition of cholesterol absorption by SCH 58053 in the mouse is not mediated via changes in the expression of mRNA for ABCA1, ABCG5, or ABCG8 in the enterocyte. J Lipid Res 43, 1864-1874.
    • (2002) J Lipid Res , vol.43 , pp. 1864-1874
    • Repa, J.J.1    Dietschy, J.M.2    Turley, S.D.3
  • 35
    • 3042522984 scopus 로고    scopus 로고
    • Cholesterol absorption is mainly regulated by the jejunal and ileal ATP-binding cassette sterol efflux transporters Abcg5 and Abcg8 in mice
    • Duan LP, Wang HH & Wang DQ (2004) Cholesterol absorption is mainly regulated by the jejunal and ileal ATP-binding cassette sterol efflux transporters Abcg5 and Abcg8 in mice. J Lipid Res 45, 1312-1323.
    • (2004) J Lipid Res , vol.45 , pp. 1312-1323
    • Duan, L.P.1    Wang, H.H.2    Wang, D.Q.3
  • 36
    • 4043124013 scopus 로고    scopus 로고
    • Niemann-Pick C1 Like 1 (NPC1L1) is the intestinal phytosterol and cholesterol transporter and a key modulator of whole-body cholesterol homeostasis
    • Davis HR Jr, Zhu LJ, Hoos LM, et al. (2004) Niemann-Pick C1 Like 1 (NPC1L1) is the intestinal phytosterol and cholesterol transporter and a key modulator of whole-body cholesterol homeostasis. J Biol Chem 279, 33586-33592.
    • (2004) J Biol Chem , vol.279 , pp. 33586-33592
    • Davis Jr, H.R.1    Zhu, L.J.2    Hoos, L.M.3
  • 37
    • 0028986624 scopus 로고
    • Regulation of hepatic 7 α-hydroxylase expression and response to dietary cholesterol in the rat and hamster
    • Horton JD, Cuthbert JA & Spady DK (1995) Regulation of hepatic 7 α-hydroxylase expression and response to dietary cholesterol in the rat and hamster. J Biol Chem 270, 5381-5387.
    • (1995) J Biol Chem , vol.270 , pp. 5381-5387
    • Horton, J.D.1    Cuthbert, J.A.2    Spady, D.K.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.