-
1
-
-
2342471392
-
Activating mutations in the epidermal growth factor receptor underlying responsiveness of non-small-cell lung cancer to gefitinib
-
Lynch TJ, Bell DW, Sordella R, et al. Activating mutations in the epidermal growth factor receptor underlying responsiveness of non-small-cell lung cancer to gefitinib. N Engl J Med 2004;350:2129-2139.
-
(2004)
N Engl J Med
, vol.350
, pp. 2129-2139
-
-
Lynch, T.J.1
Bell, D.W.2
Sordella, R.3
-
2
-
-
2342624080
-
EGFR mutations in lung cancer: Correlation with clinical response to gefitinib therapy
-
Paez JG, Janne PA, Lee JC, et al. EGFR mutations in lung cancer: correlation with clinical response to gefitinib therapy. Science 2004;304:1497-1500.
-
(2004)
Science
, vol.304
, pp. 1497-1500
-
-
Paez, J.G.1
Janne, P.A.2
Lee, J.C.3
-
3
-
-
4444344330
-
EGF receptor gene mutations are common in lung cancers from 'never smokers' and are associated with sensitivity of tumors to gefitinib and erlotinib
-
Pao W, Miller V, Zakowski M, et al. EGF receptor gene mutations are common in lung cancers from 'never smokers' and are associated with sensitivity of tumors to gefitinib and erlotinib. Proc Natl Acad Sci USA 2004;101:13306-13311.
-
(2004)
Proc Natl Acad Sci USA
, vol.101
, pp. 13306-13311
-
-
Pao, W.1
Miller, V.2
Zakowski, M.3
-
4
-
-
10844231985
-
Mutations of the epidermal growth factor receptor gene in lung cancer: Biological and clinical implications
-
Kosaka T, Yatabe Y, Endoh H, et al. Mutations of the epidermal growth factor receptor gene in lung cancer: biological and clinical implications. Cancer Res 2004;64:8919-8923.
-
(2004)
Cancer Res
, vol.64
, pp. 8919-8923
-
-
Kosaka, T.1
Yatabe, Y.2
Endoh, H.3
-
5
-
-
20044364933
-
EGFR mutations in non-small-cell lung cancer: Analysis of a large series of cases and development of a rapid and sensitive method for diagnostic screening with potential implications on pharmacologic treatment
-
Marchetti A, Martella C, Felicioni L, et al. EGFR mutations in non-small-cell lung cancer: analysis of a large series of cases and development of a rapid and sensitive method for diagnostic screening with potential implications on pharmacologic treatment. J Clin Oncol 2005;23:857-865.
-
(2005)
J Clin Oncol
, vol.23
, pp. 857-865
-
-
Marchetti, A.1
Martella, C.2
Felicioni, L.3
-
6
-
-
20044364940
-
Clinical and biological features associated with epidermal growth factor receptor gene mutations in lung cancers
-
Shigematsu H, Lin L, Takahashi T, et al. Clinical and biological features associated with epidermal growth factor receptor gene mutations in lung cancers. J Natl Cancer Inst 2005;97:339-346.
-
(2005)
J Natl Cancer Inst
, vol.97
, pp. 339-346
-
-
Shigematsu, H.1
Lin, L.2
Takahashi, T.3
-
7
-
-
17744371335
-
EGFR mutation is specific for terminal respiratory unit type adenocarcinoma
-
Yatabe Y, Kosaka T, Takahashi T, et al. EGFR mutation is specific for terminal respiratory unit type adenocarcinoma. Am J Surg Pathol 2005;29:633-639.
-
(2005)
Am J Surg Pathol
, vol.29
, pp. 633-639
-
-
Yatabe, Y.1
Kosaka, T.2
Takahashi, T.3
-
8
-
-
33644746049
-
Epidermal growth factor receptor gene mutation defines distinct subsets among small adenocarcinomas of the lung
-
Haneda H, Sasaki H, Shimizu S, et al. Epidermal growth factor receptor gene mutation defines distinct subsets among small adenocarcinomas of the lung. Lung Cancer 2006;52:47-52.
-
(2006)
Lung Cancer
, vol.52
, pp. 47-52
-
-
Haneda, H.1
Sasaki, H.2
Shimizu, S.3
-
9
-
-
34547111048
-
Distinctive evaluation of non-mucinous and mucinous subtypes of bronchioloalveolar carcinomas in EGFR and K-ras gene-mutation analyses for Japanese lung adenocarcinomas: Confirmation of the correlations with histological subtypes and gene mutations
-
Sakuma Y, Matsukuma S, Yoshihara M, et al. Distinctive evaluation of non-mucinous and mucinous subtypes of bronchioloalveolar carcinomas in EGFR and K-ras gene-mutation analyses for Japanese lung adenocarcinomas: confirmation of the correlations with histological subtypes and gene mutations. Am J Clin Pathol 2007;128:100-108.
-
(2007)
Am J Clin Pathol
, vol.128
, pp. 100-108
-
-
Sakuma, Y.1
Matsukuma, S.2
Yoshihara, M.3
-
10
-
-
27244451321
-
Epidermal growth factor receptor gene mutations and increased copy numbers predict gefitinib sensitivity in patients with recurrent non-small-cell lung cancer
-
Takano T, Ohe Y, Sakamoto H, et al. Epidermal growth factor receptor gene mutations and increased copy numbers predict gefitinib sensitivity in patients with recurrent non-small-cell lung cancer. J Clin Oncol 2005;23:6829-6837.
-
(2005)
J Clin Oncol
, vol.23
, pp. 6829-6837
-
-
Takano, T.1
Ohe, Y.2
Sakamoto, H.3
-
11
-
-
23844490782
-
Activating mutations in the tyrosine kinase domain of the epidermal growth factor receptor are associated with improved survival in gefitinib-treated chemorefractory lung adenocarcinomas
-
Taron M, Ichinose Y, Rosell R, et al. Activating mutations in the tyrosine kinase domain of the epidermal growth factor receptor are associated with improved survival in gefitinib-treated chemorefractory lung adenocarcinomas. Clin Cancer Res 2005;11:5878-5885.
-
(2005)
Clin Cancer Res
, vol.11
, pp. 5878-5885
-
-
Taron, M.1
Ichinose, Y.2
Rosell, R.3
-
12
-
-
0028789186
-
High K-ras mutation rates in goblet-cell-type adenocarcinomas of the lungs
-
Tsuchiya E, Furuta R, Wada N, et al. High K-ras mutation rates in goblet-cell-type adenocarcinomas of the lungs. J Cancer Res Clin Oncol 1995;121:577-581.
-
(1995)
J Cancer Res Clin Oncol
, vol.121
, pp. 577-581
-
-
Tsuchiya, E.1
Furuta, R.2
Wada, N.3
-
13
-
-
0030918575
-
The pattern of K-ras mutation in pulmonary adenocarcinoma defines a new pathway of tumour development in the human lung
-
Cooper CA, Carby FA, Bubb VJ, et al. The pattern of K-ras mutation in pulmonary adenocarcinoma defines a new pathway of tumour development in the human lung. J Pathol 1997;181:401-404.
-
(1997)
J Pathol
, vol.181
, pp. 401-404
-
-
Cooper, C.A.1
Carby, F.A.2
Bubb, V.J.3
-
14
-
-
33646418681
-
Optimization of patient selection for gefitinib in non-small cell lung cancer by combined analysis of epidermal growth factor receptor mutation, K-ras mutation, and Akt phosphorylation
-
Han SW, Kim TY, Jeon YK, et al. Optimization of patient selection for gefitinib in non-small cell lung cancer by combined analysis of epidermal growth factor receptor mutation, K-ras mutation, and Akt phosphorylation. Clin Cancer Res 2006;12:2538-2544.
-
(2006)
Clin Cancer Res
, vol.12
, pp. 2538-2544
-
-
Han, S.W.1
Kim, T.Y.2
Jeon, Y.K.3
-
15
-
-
15744373791
-
-
IARC: Lyon
-
Travis WD, Brambilla E, Müller-Hermelink HK, et al. Pathology and Genetics: Tumours of the Lung, Pleura, Thymus and Heart. IARC: Lyon, 2004.
-
(2004)
Pathology and Genetics: Tumours of the Lung, Pleura, Thymus and Heart
-
-
Travis, W.D.1
Brambilla, E.2
Müller-Hermelink, H.K.3
-
16
-
-
0029933372
-
K-ras oncogene activation in atypical alveolar hyperplasias of the human lung
-
Westra WH, Baas IO, Hruban RH, et al. K-ras oncogene activation in atypical alveolar hyperplasias of the human lung. Cancer Res 1996;56:2224-2228.
-
(1996)
Cancer Res
, vol.56
, pp. 2224-2228
-
-
Westra, W.H.1
Baas, I.O.2
Hruban, R.H.3
-
17
-
-
24744443517
-
Mutations of the epidermal growth factor receptor gene in atypical adenomatous hyperplasia and bronchioloalveolar carcinoma of the lung
-
Yoshida Y, Shibata T, Kokubu A, et al. Mutations of the epidermal growth factor receptor gene in atypical adenomatous hyperplasia and bronchioloalveolar carcinoma of the lung. Lung Cancer 2005;50:1-8.
-
(2005)
Lung Cancer
, vol.50
, pp. 1-8
-
-
Yoshida, Y.1
Shibata, T.2
Kokubu, A.3
-
18
-
-
0035893252
-
Analysis of lung tumor initiation and progression using conditional expression of oncogenic K-ras
-
Jackson EL, Willis N, Mercer K, et al. Analysis of lung tumor initiation and progression using conditional expression of oncogenic K-ras. Genes Dev 2001;15:3243-3248.
-
(2001)
Genes Dev
, vol.15
, pp. 3243-3248
-
-
Jackson, E.L.1
Willis, N.2
Mercer, K.3
-
19
-
-
33744788136
-
The impact of human EGFR kinase domain mutations on lung tumorigenesis and in vivo sensitivity to EGFR-targeted therapies
-
Ji H, Li D, Chen L, et al. The impact of human EGFR kinase domain mutations on lung tumorigenesis and in vivo sensitivity to EGFR-targeted therapies. Cancer Cell 2006;9:485-495.
-
(2006)
Cancer Cell
, vol.9
, pp. 485-495
-
-
Ji, H.1
Li, D.2
Chen, L.3
-
20
-
-
33748592818
-
Rapid and simple detection of hot spot point mutations of epidermal growth factor receptor, BRAF, and NRAS in cancers using the Loop-hybrid mobility shift assay
-
Matsukuma S, Yoshihara M, Kasai F, et al. Rapid and simple detection of hot spot point mutations of epidermal growth factor receptor, BRAF, and NRAS in cancers using the Loop-hybrid mobility shift assay. J Mol Diagn 2006;8:504-512.
-
(2006)
J Mol Diagn
, vol.8
, pp. 504-512
-
-
Matsukuma, S.1
Yoshihara, M.2
Kasai, F.3
-
21
-
-
33750222888
-
Novel heteroduplex method using small cytology specimens with a remarkably high success rate for analysing EGFR gene mutations with a significant correlation to gefitinib efficacy in non-small-cell lung cancer
-
Oshita F, Matsukuma S, Yoshihara M, et al. Novel heteroduplex method using small cytology specimens with a remarkably high success rate for analysing EGFR gene mutations with a significant correlation to gefitinib efficacy in non-small-cell lung cancer. Br J Cancer 2006;95:1070-1075.
-
(2006)
Br J Cancer
, vol.95
, pp. 1070-1075
-
-
Oshita, F.1
Matsukuma, S.2
Yoshihara, M.3
-
22
-
-
0035350116
-
Non-isotopic silver-stained SSCP is more sensitive than automated direct sequencing for the detection of PTEN mutations in a mixture of DNA extracted from normal and tumor cells
-
Fan X, Furnari FB, Cavenee WK, et al. Non-isotopic silver-stained SSCP is more sensitive than automated direct sequencing for the detection of PTEN mutations in a mixture of DNA extracted from normal and tumor cells. Int J Oncol 2001;18:1023-1026.
-
(2001)
Int J Oncol
, vol.18
, pp. 1023-1026
-
-
Fan, X.1
Furnari, F.B.2
Cavenee, W.K.3
-
23
-
-
0036164015
-
Natural history of pure ground-glass opacity after long-term follow-up of more than 2 years
-
Kodama K, Higashiyama M, Yokouchi H, et al. Natural history of pure ground-glass opacity after long-term follow-up of more than 2 years. Ann Thorac Surg 2002;73:386-392.
-
(2002)
Ann Thorac Surg
, vol.73
, pp. 386-392
-
-
Kodama, K.1
Higashiyama, M.2
Yokouchi, H.3
-
24
-
-
0032949035
-
Atypical adenomatous hyperplasia of the lung. Implications for the pathogenesis of peripheral lung adenocarcinoma
-
Kitamura H, Kameda Y, Ito T, et al. Atypical adenomatous hyperplasia of the lung. Implications for the pathogenesis of peripheral lung adenocarcinoma. Am J Clin Pathol 1999;111:610-622.
-
(1999)
Am J Clin Pathol
, vol.111
, pp. 610-622
-
-
Kitamura, H.1
Kameda, Y.2
Ito, T.3
|