-
1
-
-
0141789624
-
Progression of chronic kidney disease: The role of blood pressure control, proteinuria, and angiotensin-converting enzyme inhibition: a patient-level meta-analysis
-
Jafar TH, Stark PC, Schmid CH, et al. Progression of chronic kidney disease: the role of blood pressure control, proteinuria, and angiotensin-converting enzyme inhibition: a patient-level meta-analysis. Ann Intern Med 2003; 139:244-252.
-
(2003)
Ann Intern Med
, vol.139
, pp. 244-252
-
-
Jafar, T.H.1
Stark, P.C.2
Schmid, C.H.3
-
2
-
-
0035922441
-
Effects of losartan on renal and cardiovascular outcomes in patients with type 2 diabetes and nephropathy
-
Brenner BM, Cooper ME, de Zeeuw D, et al. Effects of losartan on renal and cardiovascular outcomes in patients with type 2 diabetes and nephropathy. N Engl J Med 2001; 345:861-869.
-
(2001)
N Engl J Med
, vol.345
, pp. 861-869
-
-
Brenner, B.M.1
Cooper, M.E.2
de Zeeuw, D.3
-
3
-
-
0035922447
-
Renoprotective effect of the angiotensin-receptor antagonist irbesartan in patients with nephropathy due to type 2 diabetes
-
Lewis EJ, Hunsicker LG, Clarke WR, et al. Renoprotective effect of the angiotensin-receptor antagonist irbesartan in patients with nephropathy due to type 2 diabetes. N Engl J Med 2001; 345:851-860.
-
(2001)
N Engl J Med
, vol.345
, pp. 851-860
-
-
Lewis, E.J.1
Hunsicker, L.G.2
Clarke, W.R.3
-
4
-
-
0035922444
-
The effect of irbesartan on the development of diabetic nephropathy in patients with type 2 diabetes
-
Parving HH, Lehnert H, Brochner-Mortensen J, et al. The effect of irbesartan on the development of diabetic nephropathy in patients with type 2 diabetes. N Engl J Med 2001; 345:870-878.
-
(2001)
N Engl J Med
, vol.345
, pp. 870-878
-
-
Parving, H.H.1
Lehnert, H.2
Brochner-Mortensen, J.3
-
5
-
-
33644912981
-
Independent and additive impact of blood pressure control and angiotensin II receptor blockade on renal outcomes in the irbesartan diabetic nephropathy trial: Clinical implications and limitations
-
Pohl MA, Blumenthal S, Cordonnier DJ, et al. Independent and additive impact of blood pressure control and angiotensin II receptor blockade on renal outcomes in the irbesartan diabetic nephropathy trial: clinical implications and limitations. J Am Soc Nephrol 2005; 16:3027-3037.
-
(2005)
J Am Soc Nephrol
, vol.16
, pp. 3027-3037
-
-
Pohl, M.A.1
Blumenthal, S.2
Cordonnier, D.J.3
-
6
-
-
0038155497
-
Effects of blood pressure level on progression of diabetic nephropathy: Results from the RENAAL study
-
Bakris GL, Weir MR, Shanifar S, et al. Effects of blood pressure level on progression of diabetic nephropathy: results from the RENAAL study. Arch Intern Med 2003; 163:1555-1565.
-
(2003)
Arch Intern Med
, vol.163
, pp. 1555-1565
-
-
Bakris, G.L.1
Weir, M.R.2
Shanifar, S.3
-
7
-
-
0035997523
-
Pathophysiologic and therapeutic importance of tissue ACE: A consensus report
-
Dzau VJ, Bernstein K, Celermajer D, et al. Pathophysiologic and therapeutic importance of tissue ACE: a consensus report. Cardiovasc Drugs Ther 2002; 16:149-160.
-
(2002)
Cardiovasc Drugs Ther
, vol.16
, pp. 149-160
-
-
Dzau, V.J.1
Bernstein, K.2
Celermajer, D.3
-
8
-
-
33748070612
-
-
Clin J Am Soc Nephrol, A good review of the mechanisms behind renin inhibition with some experimental and clinical observations
-
Muller DM, Luft FC. Direct renin inhibition with aliskiren in hypertension and target organ damage. Clin J Am Soc Nephrol 2006; 1:221-228. A good review of the mechanisms behind renin inhibition with some experimental and clinical observations.
-
(2006)
Direct renin inhibition with aliskiren in hypertension and target organ damage
, vol.1
, pp. 221-228
-
-
Muller, D.M.1
Luft, F.C.2
-
9
-
-
0032512094
-
Pathophysiology of progressive nephropathies
-
Remuzzi G, Bertani T. Pathophysiology of progressive nephropathies. N Engl J Med 1998; 339:1448-1456.
-
(1998)
N Engl J Med
, vol.339
, pp. 1448-1456
-
-
Remuzzi, G.1
Bertani, T.2
-
10
-
-
33646523408
-
Renal risk and renoprotection among ethnic groups with type 2 diabetic nephropathy: A post hoc analysis of RENAAL
-
An important paper correlating change in albuminuria with risk for progression of kidney disease
-
de Zeeuw D, Ramjit D, Zhang Z, et al. Renal risk and renoprotection among ethnic groups with type 2 diabetic nephropathy: a post hoc analysis of RENAAL. Kidney Int 2006; 69:1675-1682. An important paper correlating change in albuminuria with risk for progression of kidney disease.
-
(2006)
Kidney Int
, vol.69
, pp. 1675-1682
-
-
de Zeeuw, D.1
Ramjit, D.2
Zhang, Z.3
-
11
-
-
0027499036
-
Evidence of a partial escape of renin-angiotensin-aldosterone blockade in patients with acute myocardial infarction treated with ACE inhibitors
-
Borghi C, Boschi S, Ambrosioni E, et al. Evidence of a partial escape of renin-angiotensin-aldosterone blockade in patients with acute myocardial infarction treated with ACE inhibitors. J Clin Pharmacol 1993; 33:40-45.
-
(1993)
J Clin Pharmacol
, vol.33
, pp. 40-45
-
-
Borghi, C.1
Boschi, S.2
Ambrosioni, E.3
-
12
-
-
0033989542
-
Clinical implications of increased plasma angiotensin II despite ACE inhibitor therapy in patients with congestive heart failure
-
Roig E, Perez-Villa F, Morales M, et al. Clinical implications of increased plasma angiotensin II despite ACE inhibitor therapy in patients with congestive heart failure. Eur Heart J 2000; 21:53-57.
-
(2000)
Eur Heart J
, vol.21
, pp. 53-57
-
-
Roig, E.1
Perez-Villa, F.2
Morales, M.3
-
13
-
-
33749985149
-
-
Staessen JA, Li Y, Richart T. Oral renin inhibitors. Lancet 2006; 368:1449-1456. A good review of clinical results with renin inhibitors.
-
Staessen JA, Li Y, Richart T. Oral renin inhibitors. Lancet 2006; 368:1449-1456. A good review of clinical results with renin inhibitors.
-
-
-
-
14
-
-
14844363404
-
Aliskiren, a novel orally effective renin inhibitor, provides dose-dependent antihypertensive efficacy and placebo-like tolerability in hypertensive patients
-
Gradman AH, Schmieder RE, Lins RL, et al. Aliskiren, a novel orally effective renin inhibitor, provides dose-dependent antihypertensive efficacy and placebo-like tolerability in hypertensive patients. Circulation 2005; 111:1012-1018.
-
(2005)
Circulation
, vol.111
, pp. 1012-1018
-
-
Gradman, A.H.1
Schmieder, R.E.2
Lins, R.L.3
-
15
-
-
34547870403
-
The renin inhibitor aliskiren ameliorates hypertensive diabetic nephropathy in transgenic (mRen-2)27 (Ren-2) Rats
-
Feldman DL, Jin L, Miserendino-Moltini R, et al. The renin inhibitor aliskiren ameliorates hypertensive diabetic nephropathy in transgenic (mRen-2)27 (Ren-2) Rats. J Am Soc Nephrol 2005; 16:213A.
-
(2005)
J Am Soc Nephrol
, vol.16
-
-
Feldman, D.L.1
Jin, L.2
Miserendino-Moltini, R.3
-
16
-
-
34547882245
-
Aliskiren, a human renin inhibitor induces persistent renoprotection comparable to ace inhibition in double transgenic rats (DTGR) [abstract]
-
Feldman DL, Jin L, Miserendino-Moltini R, et al. Aliskiren, a human renin inhibitor induces persistent renoprotection comparable to ace inhibition in double transgenic rats (DTGR) [abstract]. Am J Hypertens 2005; 18(5 Part 2):230A.
-
(2005)
Am J Hypertens
, vol.18
, Issue.5 PART 2
-
-
Feldman, D.L.1
Jin, L.2
Miserendino-Moltini, R.3
-
17
-
-
25444454353
-
Aliskiren, a human renin inhibitor, ameliorates cardiac and renal damage in double-transgenic rats
-
Pilz B, Shagdarsuren E, Wellner M, et al. Aliskiren, a human renin inhibitor, ameliorates cardiac and renal damage in double-transgenic rats. Hypertension 2005; 46:569-576.
-
(2005)
Hypertension
, vol.46
, pp. 569-576
-
-
Pilz, B.1
Shagdarsuren, E.2
Wellner, M.3
-
18
-
-
20544440652
-
Renin inhibition: What are the therapeutic opportunities?
-
Fisher ND, Hollenberg NK. Renin inhibition: what are the therapeutic opportunities? J Am Soc Nephrol 2005; 16:592-599.
-
(2005)
J Am Soc Nephrol
, vol.16
, pp. 592-599
-
-
Fisher, N.D.1
Hollenberg, N.K.2
-
19
-
-
0031688757
-
Pathways for angiotensin II generation in intact human tissue: Evidence from comparative pharmacological interruption of the renin system
-
Hollenberg NK, Fisher ND, Price DA. Pathways for angiotensin II generation in intact human tissue: evidence from comparative pharmacological interruption of the renin system. Hypertension 1998; 32:387-392.
-
(1998)
Hypertension
, vol.32
, pp. 387-392
-
-
Hollenberg, N.K.1
Fisher, N.D.2
Price, D.A.3
-
20
-
-
85190640452
-
-
1 receptor antagonist valsartan on the angiotensin II-renin feedback interruption. J Am Soc Nephrol 2004; 15:3126-3133.
-
1 receptor antagonist valsartan on the angiotensin II-renin feedback interruption. J Am Soc Nephrol 2004; 15:3126-3133.
-
-
-
-
21
-
-
33644789557
-
-
A good summary of current theories and experimental and clinical data
-
Azizi M, Webb R, Nussberger J, Hollenberg NK. Renin inhibition with aliskiren: where are we now, and where are we going? J Hypertens 2006; 24:243-256. A good summary of current theories and experimental and clinical data.
-
(2006)
Renin inhibition with aliskiren: Where are we now, and where are we going? J Hypertens
, vol.24
, pp. 243-256
-
-
Azizi, M.1
Webb, R.2
Nussberger, J.3
Hollenberg, N.K.4
-
22
-
-
36348966827
-
The direct renin inhibitor aliskiren in combination with valsartan provides additional blood pressure-lowering effects compared with either agent alone in patients with hypertension [abstract]
-
Oparil S, Yarows SA, Patel S, et al. The direct renin inhibitor aliskiren in combination with valsartan provides additional blood pressure-lowering effects compared with either agent alone in patients with hypertension [abstract]. J Clin Hypertens 2007; 9 (Suppl A):A174.
-
(2007)
J Clin Hypertens
, vol.9
, Issue.SUPPL. A
-
-
Oparil, S.1
Yarows, S.A.2
Patel, S.3
-
23
-
-
27444447364
-
Renin, prorenin and the putative (pro)renin receptor
-
A complete basic science summary of renin and prorenin receptors and their potential impact on disease
-
Danser AH, Deinum J. Renin, prorenin and the putative (pro)renin receptor. Hypertension 2005; 46:1069-1076. A complete basic science summary of renin and prorenin receptors and their potential impact on disease.
-
(2005)
Hypertension
, vol.46
, pp. 1069-1076
-
-
Danser, A.H.1
Deinum, J.2
|