Uncertainties analysis for the plutonium dosimetry model, doses-2005, using Mayak bioassay data

Health Physics

Volumn 93, Issue 3, 2007, Pages 207-219

  Bess, John D ^a   Krahenbuhl, Melinda P ^a   Miller, Scott C ^a   Slaughter, David M ^a   Khokhryakov, Viktor V ^b   Khokhryakov, Valentin F ^b   Suslova, Klara G ^b   Vostrotin, Vadim V ^b  

^a UNIVERSITY OF UTAH   (United States)

^b Southern Urals Biophysics Institute   (Russian Federation)

Author keywords

Dosimetry, errors; Dosimetry, internal; Modeling, dose assessment; Plutonium

Indexed keywords

PLUTONIUM;

ARTICLE; AUTOPSY; BIOASSAY; COMPARATIVE STUDY; CORRELATION ANALYSIS; DOSE CALCULATION; DOSIMETRY; HUMAN; MEASUREMENT; MONTE CARLO METHOD; PRIORITY JOURNAL; RADIATION PROTECTION;

AIR POLLUTANTS, RADIOACTIVE; AUTOPSY; BIOLOGICAL ASSAY; COHORT STUDIES; HUMANS; MODELS, THEORETICAL; MONTE CARLO METHOD; OCCUPATIONAL EXPOSURE; PLUTONIUM; RADIATION DOSAGE; RADIOMETRY; RUSSIA; SMOKING; UNCERTAINTY;

EID: 34547918924     PISSN: 00179078     EISSN: None     Source Type: Journal    
DOI: 10.1097/01.HP.0000266741.42070.e8     Document Type: Article

References (89)

1. 2. Health Phys 84:726-736; 2003.
2. Akleyev AV, Grosche B, Gusev BI, Kiselev VI, Kisselev MF, Kolyado IB, Romanov S, Shoikhet YN, Neta R. Developing additional resources. Radiat Environ Biophys 41:13-18; 2002.
3. Anspaugh LR, Degteva MO, Vasilenko EK. Mayak Production Association: Introduction. Radiat Environ Biophys 41:19-22; 2002.
4. Bailey BR, Eckerman KF, Townsend LW. An analysis of a puncture wound case with medical intervention. Radiat Protect Dosim 105:509-512; 2003.
5. Beyer WH. CRC standard mathematical tables. 28th ed. Boca Raton, FL: CRC Press; 1987.
6. Birchall A, James AC. A microcomputer algorithm for solving first-order compartmental models involving recycling. Health Phys 56:857-868; 1989.
7. Boice JD Jr, Leggett RW, Ellis ED, Wallace PW, Mumma M, Cohen SS, Brill AB, Chadda B, Boecker BB, Yoder RC, Eckerman KF. A comprehensive dose reconstruction methodology for former Rocketdyne/Atomics International radiation workers. Health Phys 90:409-430; 2006.
8. Bolch WE, Farfán EB, Huh C, Huston TE, Bolch WE. Influences of parameter uncertainties within the ICRP 66 respiratory tract model: particle deposition. Health Phys 81:378-394; 2001.
9. Bolch WE, Huston TE, Farfán EB, Vernetson WG, Bolch WE. Influences of parameter uncertainties within the ICRP-66 respiratory tract model: particle clearance. Health Phys 84:421-435; 2003.
10. Chen WL, Luan YC, Shieh MC, Chen ST, Kung HT, Soong KL, Yeh YC, Chou TS, Mong SH, Wu JT, Sun CP, Deng WP, Wu MF, Shen ML. Is chronic radiation an effective prophylaxis against cancer? J Am Phys Surg 9:6-10; 2004.
11. Cheng YS, Guilmette RA, Zhou Y, Gao J, LaBone T, Whicker JJ, Hoover MD. Characterization of plutonium aerosol collected during an accident. Health Phys 87:596-605; 2004.
12. Cochran TB, Norris RS. Nuclear weapons databook: working papers, NEW 90-3 (3rd rev), soviet nuclear warhead production. Washington, DC: Natural Resources Defense Council; 1991.
13. 8. Health Phys 84:436-450; 2003.
14. Faw RE, Shultis JK. Radiological assessment: sources and doses. La Grange Park, IL: American Nuclear Society; 1999.
15. Fritsch P. Uncertainties in aerosol deposition within the respiratory tract using the ICRP 66 model: a study in workers. Health Phys 90:114-126; 2006.
16. 2. Radiat Res 150:66-82; 1998.
17. Gilbert ES, Koshurnikova NA, Sokolnikov M, Khokhryakov VF, Miller S, Preston DL, Romanov SA, Shilnikova NS, Suslova KG, Vostrotin VV. Liver cancers in Mayak workers. Radiat Res 154:246-252; 2000.
18. Gilbert ES, Koshurnikova NA, Sokolnikov ME, Shilnikova NS, Preston DL, Ron E, Okatenko PV, Khokhryakov VF, Vasilenko EK, Miller S, Eckerman K, Romanov SA. Lung cancer in Mayak workers. Radiat Res 162:505-516; 2004.
19. Griffith WC, Guilmette RA. Multiparameter analysis of fallout plutonium burdens in human liver. Radiat Protect Dosim 38:113-119; 1991.
20. Guilmette RA, Durbin PW. Scientific basis for the development of biokinetic models for radionuclide-contaminated wounds. Radiat Protect Dosim 105:213-218; 2003.
21. Guilmette RA, Romanov SA, Hahn FF, Nifatov AP, Muksinova KN, Zaytseva YV. Assessing the uniformity of plutonium alpha radiation dose in human lung: the Mayak experience. Radiat Protect Dosim 99:457-461; 2002.
22. Hahn FF, Romanov SA, Guilmette RA, Nifatov AP, Zaytseva YV, Diel JH, Allen SW, Lyovkina YV. Distribution of plutonium particles in the lungs of Mayak workers. Radiat Protect Dosim 105:81-84; 2003.
23. Hahn FF, Romanov SA, Guilmette RA, Nifatov AP, Diel JH, Zaytseva Y. Plutonium microdistribution in the lungs of Mayak workers. Radiat Res 161:568-581; 2004.
24. Hande MP, Azizova TV, Geard CR, Burak LE, Mitchell CR, Khokhryakov VF, Vasilenko EK, Brenner DJ. Past exposure to densely ionizing radiation leaves a unique permanent signature in the genome. Am J Hum Genet 72:1162-1170; 2003.
25. Harrison JD, Metivier H, Leggett RW, Nosske D, Paquet F, Phipps A, Taylor D. Reliability of the ICRP's dose coefficients for members of the public. II. Uncertainties in the absorption of ingested radionuclides and the effect of dose estimates. Radiat Protect Dosim 95:295-308; 2001.
26. 238Pu biokinetics/dosimetry model to human bioassay data. Health Phys 68:359-370; 1995.
27. Huston TE, Farfán EB, Bolch WE, Bolch WE. Influences of parameter uncertainties within the ICRP-66 respiratory tract model: a parameter sensitivity analysis. Health Phys 85:553-566; 2003.
28. International Commission on Radiological Protection. Report of the task group on reference man. Oxford: Pergamon Press; ICRP Publication 23; 1975.
29. International Commission on Radiological Protection. Limits for intakes of radionuclides by workers. Oxford: Pergamon Press; ICRP Publication 30; 1978.
30. International Commission on Radiological Protection. Age dependent doses to members of the public from intake of radionuclides. Part 2. Oxford: Pergamon Press; ICRP Publication 67; 1993.
31. International Commission on Radiological Protection. Human respiratory tract model for radiological protection. Oxford: Pergamon Press; ICRP Publication 66; 1994.
32. International Commission on Radiological Protection. Basic anatomical and physiological data for use in radiological protection: reference values. Oxford: Pergamon Press; ICRP Publication 89; 2003.
33. Jacob V, Jacob P, Meckbach R, Romanov SA, Vasilenko EK. Lung cancer in Mayak workers: interaction of smoking and plutonium exposure. Radiat Environ Biophys 44:119-129; 2005.
34. Khokhryakov VF, Suslova KG, Tsevelyova IA, Aladova EE. Classification of alpha active workplace aerosols based on coefficient of transportability as measured by the dialysis method. J Radioanal Nucl Chem 234:209-212; 1998.
35. Khokhryakov V, Suslova K, Aladova E, Vasilenko E, Miller SC, Slaughter DM, Krahenbuhl MP. Development of an improved dosimetry system for the workers at the Mayak Production Association. Health Phys 79:72-76; 2000.
36. Khokhryakov VF, Suslova KG, Vostrotin VV, Romanov SA, Menshikh ZS, Kudryavtseva TI, Filipy RE, Miller SC, Krahenbuhl MP. The development of the plutonium lung clearance model for exposure estimation of the Mayak Production Association, nuclear plant workers. Health Phys 82:425-431; 2002.
37. Khokhryakov VF, Suslova KG, Kudryavtseva TI, Schadilov AE, Vostrotin VV, Lagounova NYu, Barabanshchikova AYu. Relative role of plutonium excretion with urine and feces from human body. Health Phys 86:523-527; 2004.
38. Khokhryakov VF, Suslova KG, Vostrotin VV, Romanov SA, Eckerman KF, Krahenbuhl MP, Miller SC. Adaptation of the ICRP Publication 66 respiratory tract model to data on plutonium biokinetics for Mayak workers. Health Phys 88:125-132; 2005.
39. Khokhryakov VF, Khokhryakov VV, Suslova KG, Vostrotin VV, Shchadilov AE, Sokolova AB, Efimov AV, Krahenbuhl MP, Miller SC, Eckerman KF, Leggett RW. Progress in plutonium dosimetry development at Mayak PA. Radiat Safety Problems 1:58-79; 2006.
40. Konstantinov M, Gu D, Mehrmann V, Petkov P. Perturbation theory for matrix equations. Amsterdam, The Netherlands: Elsevier Science BV; 2003.
41. Koshurnikova NA, Shilnikova NS, Okatenko PV, Kreslov VV, Bolotnikova MG, Sokolnikov ME, Khokhriakov VF, Suslova KG, Vassilenko EK, Romanov SA. Characteristics of the cohort of workers at the Mayak nuclear complex. Radiat Res 152:352-363; 1999.
42. Koshurnikova NA, Gilbert ES, Sokolnikov M, Khokhryakov VF, Miller S, Preston DL, Romanov SA, Shilnikova NS, Suslova KG, Vostrotin VV. Bone cancers in Mayak workers. Radiat Res 154:237-245; 2000.
43. Krahenbuhl MP, Slaughter DM, Wilde JL, Bess JD, Miller SC, Khokhryakov VF, Suslova KG, Vostrotin VV, Romanov SA, Menshikh ZS, Kudryavtseva TI. The historical and current application of the FIB-1 model to assess organ dose from plutonium intakes in Mayak workers. Health Phys 82:445-454; 2002.
44. Krahenbuhl MP, Bess JD, Wilde JL, Vostrotin VV, Suslova KG, Khokhryakov VF, Slaughter DM, Miller SC. Uncertainties analysis of doses resulting from chronic inhalation of plutonium at the Mayak Production Association. Health Phys 89:33-45; 2005.
45. Kreisheimer M, Koshurnikova NA, Nekolla E, Khokhryakov VF, Romanov SA, Sokolnikov ME, Shilnikova NS, Okatenjo PK, Kellerer AM. Lung cancer mortality among male nuclear workers of the Mayak facilities in the former Soviet Union. Radiat Res 154:2-11; 2000.
46. Kreisheimer M, Sokolnikov ME, Koshurnikova NA, Khokhryakov VF, Romanow SA, Shilnikova NS, Okatenko PV, Nekolla EA, Kellerer AM. Lung cancer mortality among nuclear workers of the Mayak facilities in the former Soviet Union. An updated analysis considering smoking as the main confounding factor. Radiat Environ Biophys 42:129-235; 2003.
47. Latysheva M. The Russian nuclear power industry 20 years after Chernobyl. Russian Life 49:42-50; 2006.
48. Leggett RW. Reliability of the ICRP's dose coefficients for members of the public. I. Sources of uncertainty in the biokinetic models. Radiat Protect Dosim 95:199-213; 2001.
49. Leggett RW. Reliability of the ICRP's dose coefficients for members of the public. III. Plutonium as a case study of uncertainties in the systemic biokinetics of radionuclides. Radiat Protect Dosim 106:103-120; 2003.
50. Leggett RW, Eckerman KF, Khokhryakov VF, Suslova KG, Krahenbuhl MP, Miller SC. Mayak worker study: an improved biokinetic model for reconstructing doses from internally deposited plutonium. Radiat Res 164:111-122; 2005.
51. Lubchanskiy ER, Romanov SA. The basic directions and results of activities of Branch No. 1 of the State Research Center of the Russian Federation "Biophysics Institute" (FIB-1). Health Phys 79:9-10; 2000.
52. Luciani A, Polig E. Verification and modification of the ICRP 67 model for plutonium dose calculation. Health Phys 78:303-310; 2000.
53. Luciani A, Doerfel H, Polig E. Sensitivity analysis of the urinary excretion of plutonium. Radiat Protect Dosim 93:179-183; 2001.
54. Lyons LE. A practical guide to data analysis for physical science students. Cambridge, UK: Cambridge University Press; 1991.
55. Marsh JW, Bailey MR, Birchall A. A step-by-step procedure to aid the assessment of intake and doses from measurement data. Radiat Protect Dosim 114:491-508; 2005.
56. McKay MD, Conover WJ, Beckman RJ. A comparison of three methods for selecting values of input variables in the analysis of output from a computer code. Technometrics 21:239-245; 1979.
57. Miller G, Inkret WC, Schillaci ME, Martz HF, Little TT. Analyzing bioassay data using Bayesian methods - a primer. Health Phys 78:598-613; 2000.
58. Miller SC, Lloyd RD, Bruenger FW, Krahenbuhl MP, Polig E, Romanov SA. Comparisons of the skeletal locations of putative plutonium-induced osteosarcomas in humans with those in beagle dogs and with naturally occurring tumors in both species. Radiat Res 160:517-523; 2003.
59. Muksinova K, Kirillova EN, Zakharova ML, Revina VS, Neta R. A repository of bio-specimens from Mayak workers exposed to protracted radiation. Health Phys 90:263-265; 2006.
60. O'Brien RS. Assessment of intakes of mixtures of radionuclides. Radiat Protect Dosim 105:95-100; 2003.
61. 239Pu. Radiat Protect Dosim 113:3-13; 2005.
62. Peace MS. Practical experience of the application of ICRP models in internal dose assessment. Radiat Protect Dosim 105:33-38; 2003.
63. Polig E. Labels of surface-seeking radionuclides in the human skeleton. Health Phys 72:19-33; 1997.
64. Polig E. Modeling the distribution and dosimetry of internal emitters: a review of mathematical procedures using matrix methods. Health Phys 81:492-501; 2001.
65. Polig E, Bruenger FW, Lloyd RD, Miller SC. Biokinetic and dosimetric model of plutonium in the dog. Health Phys 78:182-190; 2000.
66. Puncher M, Marsh JW, Birchall A. Obtaining an unbiased estimate of intake in routine monitoring when the time of intake is unknown. Radiat Protect Dosim 118:280-289: 2006.
67. Romanov SA, Vasilenko EK, Khokhryakov VF, Jacob P. Studies on the Mayak nuclear workers: dosimetry. Radiat Environ Biophys 41:23-28; 2002.
68. Romanov SA, Guilmette RA, Hahn FF, Nifatov AP, Zaytseva YV, Lyovkina YV. Modifying the ICRP 66 dosimetry model based on results obtained from Mayak plutonium workers. Radiat Protect Dosim 106:85-90: 2003.
69. Saliby E. Descriptive sampling: a better approach to Monte Carlo simulation. J Opl Res Soc 41:1133-1142; 1990.
70. Saliby E. Descriptive sampling: an improvement over Latin hypercube sampling. In: Proceedings of a Winter Simulation Conference. Atlanta, GA: The Society for Computer Simulation International; 1997: 230-233.
71. Saliby E, Pacheco F. An empirical evaluation of sampling methods in risk analysis simulation: quasi-Monte Carlo, descriptive sampling, and Latin hypercube sampling. In: Proceedings of a Winter Simulation Conference. San Diego, CA: The Society for Computer Simulation International; 2002: 1606-1610.
72. Saliby E, Paul RJ. Implementing descriptive sampling in three phase discrete event simulation models. J Opl Res Soc 44:147-160; 1993.
73. Schafer DW, Gilbert ES. Some statistical implications of dose uncertainty in radiation dose-response analyses. Radiat Res 166:303-312; 2006.
74. Scott BR, Peterson VL. Risk estimates for deterministic health effects of inhaled weapons grade plutonium. Health Phys 85:280-293; 2003.
75. Seixas NS, Robins TG, Moulton LH. The use of geometric and arithmetic mean exposures in occupational epidemiology. Am J Ind Med 14:465-477; 1988.
76. Seligman PJ. The U.S.-Russian radiation health effects research program in the Southern Urals. Health Phys 79:3-8; 2000.
77. Shapiro J. Radiation protection: a guide for scientists and physicians. 3rd ed. Cambridge: Harvard University Press; 1990.
78. Shilnikova NS, Preston DL, Ron E, Gilbert ES, Vassilenko EK, Romanov SA, Kuznetsova IS, Sokolnikov ME, Okatenko PV, Kreslov VV, Koshurnikova NA. Cancer mortality risk among workers at the Mayak nuclear complex. Radiat Res 159:787-788; 2003.
79. Simon SL, Kleinerman RA, Ron E, Bouville A. Uses of dosimetry in radiation epidemiology. Radiat Res 166:125-127; 2006a.
80. Simon SL, Bouville A, Kleinerman R, Ron E. Dosimetry for epidemiological studies: learning from the past, looking to the future. Radiat Res 166:313-318; 2006b.
81. 239Pu using new ICRP internal dosimetry models. Radiat Protect Dosim 105:361-364; 2003.
82. Skorokhod AV, Hoppensteadt FC, Salehi H. Random perturbation methods and applications in science and engineering. New York: Springer-Verlag; 2002.
83. Speed J, Birchall A, Bull R, Cockerill R, Jarvis NS, Marsh JW, Peace MS, Roberts G, Scarlett C, Spencer D, Stewart P. UK Laboratory intercomparison on internal dosimetry. Radiat Protect Dosim 104:221-229; 2003.
84. Suslova KG, Khokhryakov VF, Tokarskaya ZB, Nifatov AP, Krahenbuhl MP, Miller SC. Extrapulmonary organ distribution of plutonium in healthy workers exposed by chronic inhalation at the Mayak Production Association. Health Phys 82:432-444; 2002.
85. Suslova KG, Khokhryakov VF, Tokarskaya ZB, Nifatov AP, Sokolova AB, Kudryavtzeva TI, Miller SC, Krahenbuhl MP. The effect of state of health on organ distribution and excretion of systemic plutonium in the Mayak workers. Radiat Protect Dosim 105:229-233; 2003.
86. Suslova KG, Khokhryakov VF, Tokarskaya ZB, Nifatov AP, Sokolova AB, Miller SC, Krahenbuhl MP. Modifying effects of health status, physiological, and dosimetric factors on extrapulmonary organ distribution and excretion of inhaled plutonium in workers at the Mayak Production Association. Health Phys 90:299-311; 2006.
87. Tokarskaya ZB, Okladnikova ND, Belyaeva ZD, Drozhko EG. Multifactorial analysis of lung cancer dose-response relationships for workers at the Mayak nuclear enterprise. Health Phys 73:899-905; 1997.
88. Tokarskaya ZB, Scott BR, Zhuntova GV, Okladnikova ND, Belyaeva ZD, Khokhryakov VF, Schöllnberger H, Vasilenko EK. Interaction of radiation and smoking in lung cancer induction among workers at the Mayak nuclear enterprise. Health Phys 83:833-856; 2002.
89. Xue X, Kim MY, Shore RE. Estimation of health risks associated with occupational radiation exposure: addressing measurement error and minimum detectable exposure level. Health Phys 91:582-591; 2006.