A synthetic polypeptide based on human E-cadherin inhibits invasion of human intestinal and liver cell lines by Listeria monocytogenes

Journal of Medical Microbiology

Volumn 56, Issue 8, 2007, Pages 1011-1016

  Sahu, Saura C ^a   Gaines, Dennis W ^a   Williams, Kristina M ^a   Raybourne, Richard B ^a  

^a CENTER FOR DRUG EVALUATION AND RESEARCH   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

HISTIDYLASPARTYLTRYPTOPHYLVALYLISOLEUCYLPROLYLPROLYLISOLEUCYLSERYLCYSTEINYLPROLY LGLUTAMYLASPARAGINYLGLUTAMYLLYSYLGLYCYLGLUTAMYLPHENYLALANYLPROLYLPROLYLLYSYLASPA RAGINYLLEUCYLVALYLGLUTAMINYLISOLEUCYLLYSYLSERYLASPARAGINYLARGINYLASPARTYLLYSINE; HISTIDYLASPARTYLTRYPTOPHYLVALYLISOLEUCYLPROLYLPROLYLISOLEUCYLSERYLCYSTEINYLPROLY LGLUTAMYLASPARAGINYLGLUTAMYLLYSYLGLYCYLPROLYLPHENYLALANYLPROLYLPROLYLLYSYLASPARA GINYLLEUCYLVALYLGLUTAMINYLISOLEUCYLLYSYLSERYLASPARAGINYLARGINYLASPARTYLLYSINE; INTERNALIN A; MEMBRANE PROTEIN; POLYPEPTIDE; UNCLASSIFIED DRUG; UVOMORULIN;

AMINO ACID SUBSTITUTION; ARTICLE; CELL INVASION; CELL STRAIN; CELL STRAIN CACO 2; CELL STRAIN HEPG2; CELL STRAIN TIB73; CELL TYPE; CONTROLLED STUDY; EPITHELIUM CELL; HOST CELL; HUMAN; HUMAN CELL; IN VITRO STUDY; INHIBITION KINETICS; INTESTINE CELL; LISTERIA MONOCYTOGENES; LIVER CELL; MOLECULAR INTERACTION; MOUSE; NONHUMAN; PRIORITY JOURNAL;

AMINO ACID SEQUENCE; ANIMALS; BACTERIAL PROTEINS; CACO-2 CELLS; CADHERINS; CATTLE; CELL LINE; HEPATOCYTES; HUMANS; INTESTINES; LISTERIA INFECTIONS; LISTERIA MONOCYTOGENES; MICE; MOLECULAR SEQUENCE DATA; PEPTIDES; SPECIES SPECIFICITY; VIRULENCE; VIRULENCE FACTORS;

EID: 34547900289     PISSN: 00222615     EISSN: None     Source Type: Journal    
DOI: 10.1099/jmm.0.47194-0     Document Type: Article

References (20)

1. Alexander, J. E., Andrew, P. W., Jones, D. & Roberts, I. S. (1990). Development of an optimized system for electroporation of Listeria species. Lett Appl Microbiol 10, 179-181.
2. da Silva Tatley, F., Aldwell, F. E., Dunbier, A. K. & Guilford, P. J. (2003). N-terminal E-cadherin peptides act as decoy receptors for Listeria monocytogenes. Infect Immun 71, 1580-1583.
3. Dramsi, S., Biswas, I., Maguin, E, Braun, L., Mastroeni, P. & Cossart, P. (1995). Entry of Listeria monocytogenes into hepatocytes requires expression of inIB, a surface protein of the internalin multigene family. Mol Microbiol 16, 251-261.
4. Fortinea, N., Trieu-Cuot, P., Gaillot, O., Pellegrini, E., Berche, P. & Gaillard, J. L. (2000). Optimization of green fluorescent protein expression vectors for in vitro and in vivo detection of Listeria monocytogenes. Res Microbiol 151, 353-360.
5. Gregory, S. H., Barczynski, L. K. & Wing, E. J. (1992). Effector function of hepatocytes and Kupffer cells in the resolution of systemic bacterial infections. J Leukoc Biol 51, 421-424.
6. Khelef, N., Lecuit, M., Bierne, H. & Cossart, P. (2006). Species specificity of the Listeria monocytogenes MB protein. Cell Microbiol 8, 457-470.
7. Lebrun, M., Mengaud, J., Ohayon, H., Nato, F. & Cossart, P. (1996). Internalin must be on the bacterial surface to mediate entry of Listeria monocytogenes into epithelial cells. Mol Microbiol 21, 579-592.
8. Lecuit, M., Dramsi, S., Gottardi, C., Fedor-Chaiken, M., Gumbiner, B. & Cossart, P. (1999). A single amino acid in E-cadherin responsible for host specificity towards the human pathogen Listeria monocytogenes. EMBO J 18, 3956-3963.
9. Lecuit, M., Vandormael-Pournin, S., Lefort, J., Huerre, M., Gounon, P., Dupuy, C., Babinet, C. & Cossart, P. (2001). A transgenic model for listeriosis: role of internalin in crossing the intestinal barrier. Science 292, 1722-1725.
10. Lingnau, A., Domann, E., Hudel, M., Bock, M., Nichterlein, T., Wehland, J. & Chakraborty, T. (1995). Expression of the Listeria monocytogenes EGD inlA and inlB genes, whose products mediate bacterial entry into tissue culture cell lines, by PrfA-dependent and - independent mechanisms. Infect Immun 63, 3896-3903.
11. Mengaud, J., Ohayon, H., Gounon, P., Mege, R. M. & Cossart, P. (1996a). E-cadherin is the receptor for internalin, a surface protein required for entry of L. monocytogenes into epithelial cells. Cell 84, 923-932.
12. Mengaud, J., Lecuit, M., Lebrun, M., Nato, F., Mazie, J. C. & Cossart, P. (1996b). Antibodies to the leucine-rich repeat region of internalin block entry of Listeria monocytogenes into cells expressing E-cadherin. Infect Immun 64, 5430-5433.
13. Mohan, R., Lee, B. & Panjwani, N. (1995). Molecular cloning of the E-cadherin cDNAs from rabbit corneal epithelium. Curr Eye Res 14, 1136-1145.
14. Nightingale, K. K., Windham, K., Martin, K. E., Yeung, M. & Wiedmann, M. (2005). Select Listeria monocytogenes subtypes commonly found in foods carry distinct nonsense mutations in inlA, leading to expression of truncated and secreted internalin A, and are associated with a reduced invasion phenotype for human intestinal epithelial cells. Appl Environ Microbiol 71, 8764-8772.
15. Pizarro-Cerda, J. & Cossart, P. (2006). Subversion of cellular functions by Listeria monocytogenes. J Pathol 208, 215-223.
16. Portnoy, D. A., Auerbuch, V. & Glomski, I. J. (2002). The cell biology of Listeria monocytogenes infection: the intersection of bacterial pathogenesis and cell-mediated immunity. J Cell Biol 158, 409-414.
17. Raybourne, R. B. & Bunning, V. K. (1994). Bacterium-host cell interactions at the cellular level: fluorescent labeling of bacteria and analysis of short-term bacterium-phagocyte interaction by flow cytometry. Infect Immun 62, 665-672.
18. Shen, Y., Naujokas, M., Park, M. & Ireton, K. (2000). InIB-dependent internalization of Listeria is mediated by the Met receptor tyrosine kinase. Cell 103, 501-510.
19. Smith, M. A., Takeuchi, K., Brackett, R. E., McClure, H. M., Raybourne, R. B., Williams, K. M., Babu, U. S., Ware, G. O., Broderson, J. R. & Doyle, M. P. (2003). Nonhuman primate model for Listeria monocytogenes-induced stillbirths. Infect Immun 71, 1574-1579.
20. Xie, H., Rayboume, R. B., Babu, U. S., Lillehoj, H. S. & Heckert, R. A. (2003). CpG-induced immunomodulation and intracellular bacterial killing in a chicken macrophage cell line. Dev Comp Immunol 27, 823-834.