Diverse inhibitory actions of quaternary ammonium cholinesterase inhibitors on Torpedo nicotinic ACh receptors transplanted to Xenopus oocytes

British Journal of Pharmacology

Volumn 151, Issue 8, 2007, Pages 1280-1292

  Olivera Bravo, Silvia ^a,b   Ivorra, Isabel ^a   Morales, Andrés ^a  

^a UNIVERSITY OF ALICANTE   (Spain)

^b Molecular Neuroscience Unit of the IIBCE   (Uruguay)

Author keywords

Allosteric modulation; BW284c51; Decamethonium; Edrophonium; Nicotinic acetylcholine receptors; Quaternary ammonium molecules

Indexed keywords

1,5 BIS(4 ALLYLDIMETHYLAMMONIUMPHENYL)PENTAN 3 ONE DIBROMIDE; CHOLINESTERASE INHIBITOR; DECAMETHONIUM; EDROPHONIUM; NICOTINIC RECEPTOR; QUATERNARY AMMONIUM DERIVATIVE;

ALLOSTERISM; ANIMAL CELL; ARTICLE; CHANNEL GATING; COMPETITIVE INHIBITION; CONTROLLED STUDY; DESENSITIZATION; DOSE RESPONSE; DRUG BINDING; DRUG MECHANISM; ELECTRIC CURRENT; ELECTROPLAQUE; ENZYME INHIBITION; FEMALE; INHIBITION KINETICS; MEMBRANE CONDUCTANCE; NONHUMAN; OOCYTE; PRIORITY JOURNAL; PROTEIN FUNCTION; PROTEIN PURIFICATION; TORPEDO MARMORATA; XENOPUS LAEVIS;

ACETYLCHOLINE; ANIMALS; BENZENAMINIUM, 4,4'-(3-OXO-1,5-PENTANEDIYL)BIS(N,N-DIMETHYL-N-2-PROPENYL-), DIBROMIDE; BINDING SITES; CELL MEMBRANE; CHOLINESTERASE INHIBITORS; DECAMETHONIUM COMPOUNDS; DOSE-RESPONSE RELATIONSHIP, DRUG; DRUG SYNERGISM; EDROPHONIUM; ELECTRIC CONDUCTIVITY; ELECTROPHYSIOLOGY; ION CHANNELS; OOCYTES; RECEPTORS, NICOTINIC; TORPEDO; XENOPUS;

EID: 34547890229     PISSN: 00071188     EISSN: 14765381     Source Type: Journal    
DOI: 10.1038/sj.bjp.0707329     Document Type: Article

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