Effects of tramadol on myocardial ischemia-reperfusion injury

Scandinavian Cardiovascular Journal

Volumn 41, Issue 4, 2007, Pages 242-247

  Bilir, Ayten ^a   Erkasap, Nilufer ^a   Koken, Tulay ^b   Gulec, Sacit ^a   Kaygisiz, Ziya ^a   Tanriverdi, Belkis ^a   Kurt, Imran ^a  

^a ESKISEHIR OSMANGAZI UNIVERSITY   (Turkey)

^b AFYON KOCATEPE UNIVERSITY   (Turkey)

Author keywords

Antioxidant; Ischemia; Myocardial; Reperfusion; Tramadol

Indexed keywords

CREATINE KINASE MB; GLUTATHIONE PEROXIDASE; LACTATE DEHYDROGENASE; MALONALDEHYDE; SODIUM CHLORIDE; SUPEROXIDE DISMUTASE; TRAMADOL;

ANIMAL TISSUE; ANTIOXIDANT ACTIVITY; ARTICLE; BIOCHEMISTRY; CONTROLLED STUDY; CORONARY ARTERY BLOOD FLOW; ENZYME ACTIVITY; HEART HEMODYNAMICS; HEART MUSCLE DP-DT; HEART MUSCLE ISCHEMIA; HEART PROTECTION; ISOLATED HEART; MALE; NONHUMAN; OXIDATIVE STRESS; PRIORITY JOURNAL; RAT; REPERFUSION INJURY; SYSTOLIC BLOOD PRESSURE; TIME; TISSUE HOMOGENATE; TREATMENT OUTCOME;

ANIMALS; CARDIOTONIC AGENTS; DISEASE MODELS, ANIMAL; HEART; MALE; MYOCARDIAL REPERFUSION INJURY; OXIDATIVE STRESS; RATS; RATS, SPRAGUE-DAWLEY; TRAMADOL;

EID: 34547887659     PISSN: 14017431     EISSN: 16512006     Source Type: Journal    
DOI: 10.1080/14017430701227747     Document Type: Article

References (18)

1. Santander, SM Ferez, Marquez, MF, Duque, MA Pena, Sanchez, R Ocaranza, Almaguer, E De la Pena and Lidt, G. Eid (2004) Myocardial reperfusion injury. Rev Esp Cardiol., 57, pp. 9-21.
2. Toledo-Pereyra, LH, Lopez-Neblina, F. and Toledo, AH. (2004) Reactive oxygen species and molecular biology of ischemia/reperfusion. Ann Transplant., 9, pp. 81-83.
3. Müller, B. and Wilsman, K. (1984) Cardiac and hemodynamic effects of centrally acting analgesics tramadol and pentazocine in anaesthetized rabbits and isolated guinea-pig atria and papillary muscles. Drug Res., 34, pp. 430-433.
4. Groban, L., Vernon, JC and Butterworth, J. (2004) Intrathecal morphine reduces infarct size in a rat model of ischemia-reperfusion injury. Anesth Analg., 98, pp. 903-909.
5. McPherson, BC and Yao, Z. (2001) Signal transduction of opioid-induced cardioprotection in ischemia-reperfusion. Anesthesiology., 94, pp. 1082-1088.
6. Ellmauer, S., Dick, W., Otto, S. and Muller, H. (1994) Different opioids in patients at cardiovascular risk. Comparison of centrally and peripheral hemodynamic adverse effects. Anaesthesist., 43, pp. 743-749.
7. Ohkawa, H., Ohishi, N. and Yagi, K. (1979) Assay for lipid peroxidase in animal tissues by thiobarbituric acid reaction. Anal Biochem., 95, pp. 351-358.
8. Song, W., Shin, J., Lee, J., Kim, H. and Edelberg, JM (2005) A potent opiate agonist protects against myocardial stunning during myocardial ischemia and reperfusion in rats. Coron Artery Dis., 16, pp. 407-410.
9. Dernek, S., Ikizler, M., Erkasap, N., Ergun, B., Koken, T. and Yilmaz, K. (2004) Cardioprotection with resveratrol pretreatment: Improved beneficial effects over standard treatment in rat hearts after global ischemia. Scand Cardiovasc J., 38, pp. 245-254.
10. Zweier, JL. (1988) Measurement of superoxide derived free radicals in the reperfused heart: Evidence for a free radical mechanism of reperfusion injury. J Biol Chem., 263, pp. 1353-1357.
11. Polat, A. and Emre, MH. (2006) Effects of melatonin or acetylsalicylic acid on gastric oxidative stress after bile duct ligation in rats. J Gastroenerol., 41, pp. 433-439.
12. Kaya, T., Gursoy, S., Karadas, B., Sarac, B., Kafali, H. and Soydan, AS. (2003) High-concentration tramadol-induced vasodilatation in rabbit aorta is mediated by both endothelium-dependent and -independent mechanisms. Acta Pharmacol Sin., 4, pp. 385-389.
13. Stefano, GB. (1998) Autoimmunovascular regulation: Morphine and ancondamide and ancondamide stimulated nitric oxide release. J Neuroimmunol., 83, pp. 70-76.
14. Wang, TL, Chang, H., Hung, CR and Tseng, YZ. (1997) Attenuation of neutrophil and endothelial activation by intravenous morphine in patients with acute myocardial infarction. Am J Cardiol., 80, pp. 1532-1535.
15. Close, BR. (2005) Tramadol: Does it have a role in emergency medicine. Emerg Med Australas., 17, pp. 73-83.
16. Zaugg, M., Luchinetti, E., Uecker, M., Pasch, T. and Schaub, MC. (2003) Anaesthetics and cardiac preconditioning. Part I. Signalling and cytoprotective mechanisms. Br J Anaesth., 91, pp. 551-565.
17. Zhang, Y., Irwin, MB and Wong, TM. (2004) Remifentanyl preconditioning protects against ischemic injury in the intact rat heart. Anesthesiology., 101, pp. 918-923.
18. Soong, Y., Zhao, GM and Szeto, HH. (2002) A highly potent peptide analgesic that protects against ischemia-reperfusion-induced myocardial stunning. Am J Physiol Heart Circ Physiol., 283, pp. 783-791.