The effect of aprotinin on brain ischemic-reperfusion injury after hemorrhagic shock in rats: An experimental study

Journal of Trauma - Injury, Infection and Critical Care

Volumn 63, Issue 2, 2007, Pages 373-378

  Eser, Olcay ^a,c   Kalkan, Erdal ^b   Cosar, Murat ^a   Buyukbas, Sadik ^b   Avunduk, Mustafa Cihat ^b   Aslan, Adem ^a   Kocabas, Volkan ^b  

^a AFYON KOCATEPE UNIVERSITY   (Turkey)

^b SELCUK UNIVERSITY   (Turkey)

^c NONE   (Turkey)

Author keywords

Aprotinin; Brain injury; Experimental; Hemorrhagic shock; Ischemia; Reperfusion

Indexed keywords

APROTININ; ISOTONIC SOLUTION; MALONALDEHYDE; MYELOPEROXIDASE; SERINE PROTEINASE INHIBITOR; SUPEROXIDE DISMUTASE;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; APOPTOSIS; ARTICLE; BIOCHEMISTRY; BRAIN ISCHEMIA; BRAIN TISSUE; DRUG EFFECT; DRUG TISSUE LEVEL; EXPERIMENTAL STUDY; FEMORAL VEIN; HEMORRHAGIC SHOCK; HISTOPATHOLOGY; MALE; MORPHOLOGY; NERVOUS TISSUE; NONHUMAN; PRIORITY JOURNAL; RAT; REPERFUSION INJURY; SAMPLING; SYSTOLIC BLOOD PRESSURE;

ANIMALS; APOPTOSIS; APROTININ; BRAIN ISCHEMIA; DISEASE MODELS, ANIMAL; HEMOSTATICS; LIPID PEROXIDATION; MALE; MALONDIALDEHYDE; PROBABILITY; RANDOM ALLOCATION; RATS; RATS, SPRAGUE-DAWLEY; REACTIVE OXYGEN SPECIES; REFERENCE VALUES; REPERFUSION INJURY; RISK ASSESSMENT; SENSITIVITY AND SPECIFICITY; SEVERITY OF ILLNESS INDEX; SHOCK, HEMORRHAGIC; SUPEROXIDE DISMUTASE; SURVIVAL RATE;

EID: 34547866773     PISSN: 00225282     EISSN: 15298809     Source Type: Journal    
DOI: 10.1097/01.ta.0000236054.42254.b7     Document Type: Article

References (37)

1. Eren S, Esme H, Balci AE, et al. The effect of aprotinin on ischemia-reperfusion injury in an in situ normothermic ischemic lung model. Eur J Cardiothorac Surg. 2003;23:60-65.
2. Pruefer D, Buerke U, Khalil M, et al. Cardioprotective effects of the serine protease inhibitor aprotinin after regional ischemia and reperfusion on the beating heart. J Thorac Cardiovasc Surg. 2002;124:942-949.
3. Zhao Z, Vinten-Johansen J. Myocardial apoptosis and ischemic preconditioning. Cardiovasc Res. 2002;55:438.
4. Fleckenstein AE, Smith SL, Linseman KL, Beuving LJ, Hall ED. Comparison of the efficacy of mechanistically different antioxidants in the rat hemorrhagic shock model. Circ Shock. 1991;35:223-230.
5. Hamano K, Tsuboi H, Seyama A, Esato K. Shock-reinfusion injury to the central organs and the effect of free radical scavengers in the rat. Surg Today. 1993;23:891-896.
6. Kanko M, Maral H, Akbas MH, et al. Protective effects of clopidogrel on oxidant damage in a rat model of acute ischemia. Tohoku J Exp Med. 2005;205:133-139.
7. Pruefer D, Makowski J, Dahm M, et al. Aprotinin inhibits leukocyte-endothelial cell interactions after hemorrhage and reperfusion. Ann Thorac Surg. 2003;75:210-216.
8. Weiss SJ. Tissue destruction by neutrophils. N Engl J Med. 1989;320:365-376.
9. Nagaoka H, Katori M. Inhibition of formation by a kallikrein inhibitor during extracorporeal circulation in open heart surgery. Circulation. 1975;52:325-332.
10. van Oeveren W, Jansen NJ, Bidstrup BP, et al. Effects of aprotinin on haemostatic mechanism during cardiopulmonary bypass. Ann Thorac Surg. 1987;44:640-645.
11. Lord RA, Roath OS, Thompson JF, Chant AD, Francis JL. Effect of aprotinin on neutrophil function after major vascular surgery. Br J Surg. 1992;79:517-521.
12. Ilhan A, Gurel A, Armutcu F, et al. Ginkgo biloba prevents mobile phone-induced oxidative stress in rat brain. Clin Chim Acta. 2004;340:153-162.
13. Sun Y, Oberley LW, Li Y. A simple method for clinical assay of superoxide dismutase. Clin Chem. 1988;34:497-500.
14. Durak I, Yurtarslanl Z, Canbolat O, Akyol O. A methodological approach to superoxide dismutase (SOD) activity assay based on inhibition of nitroblue tetrazolium (NBT) reduction. Clin Chim Acta. 1993;214:103-104.
15. Draper HH, Hadley M. Malondialdehyde determination as index of lipid peroxidation. Methods Enzymol. 1990;186:421-431.
16. Shires GT, Barber AE, Illner HP. Current status of resuscitation: solutions including hypertonic saline. Adv Surg. 1995;28:133-170.
17. Rotstein OD. Modeling the two-hit hypothesis for evaluating strategies to prevent organ injury after shock/resuscitation. J Trauma. 2003;54(Suppl 5):203-206.
18. Falk JL, O'Brien JF, Kerr R. Fluid resuscitation in traumatic hemorrhagic shock. Crit Care Clin. 1992;8:323-340.
19. Sies H. Oxidative stress: oxidants and antioxidants. Exp Physiol. 1997;82:291-295.
20. Glantzounis GK, Tselepis AD, Tambaki AP, et al. Laparoscopic surgery-induced changes in oxidative stress markers in human plasma. Surg Endosc. 2001;15:1315-1319.
21. Haimovici H, Enrico A. Pathophysiology of skeletal muscle ischemia-reperfusion injury. In: Haimovici H, ed. Haimovici's Vascular Surgery Principles and Techniques. 4th ed. Cambridge, MA: Blackwell Science; 1996:498-506.
22. Roberts RF, Nishanian GP, Carey JN, et al. Addition of aprotinin to organ preservation solutions decreases lung reperfusion injury. Ann Thorac Surg. 1998;66:225-230.
23. Mietkiewski E, Lichota E, Legiecka B, Palgan E, Staniszewski L, Pietrzak-Nowacka M. Effects of kinin, kallikrein and its inhibitor on certain indices of cell-mediated immunity and humoral immunity in rabbits. Acta Physiol Pol. 1980;31:71-79.
24. Verstreate M. Clinical application of inhibitors of fibrinolysis. Drugs. 1985;29:236-261.
25. Kamiya T, Katayama Y, Kashiwagi F. The role of bradykinin in mediating ischemic brain edema in rats. Stroke. 1993;24:571-576.
26. Aoki M, Jonas RA, Nomura F, et al. Effects of aprotinin on acute recovery of cerebral metabolism in piglets after hypothermic circulatory arrest. Ann Thorac Surg. 1994;58:146-153.
27. Sunamori M, Sultan I, Suzuki A. Effect of aprotinin to improve myocardial viability in myocardial preservation followed by reperfusion. Ann Thorac Surg. 1991;52:971-978.
28. Dadoukis J, Angouridakis K, Aletras H. The action of the basic trypsin inhibitor, Trasylol, on shock resulting from occlusion of the superior mesenteric artery. Experimental study. J Int Med Res. 1981;9:31-38.
29. Kishimoto A, Kajikawa N, Tabuchi H, Shiota M, Nishizuka Y. Calcium-dependent neural proteases, widespread occurrence of a species of protease, active at lower concentrations of calcium. J Biochem. 1981;90:889-892.
30. Granger DN, Korthuis RJ. Physiologic mechanisms of postischemic tissue injury. Annu Rev Physiol. 1995;57:311-332.
31. Zimmerman BJ, Grisham MB, Granger DN. Role of oxidants in ischemia/reperfusion-induced granulocyte infiltration. Am J Physiol. 1990;258:185-190.
32. Cuzzocrea S, Costantino G, Mazzon E, Micali A, De Sarro A, Caputi AP. Beneficial effects of melatonin in a rat model of splanchnic artery occlusion and reperfusion. J Pineal Res. 2000;28:52-63.
33. Winterbourn CC, Kettle AJ. Reactions of myeloperoxidase with superoxide and hydrogen peroxide: significance for its function in the neutrophil. Basic Life Sci. 1988;49:823-827.
34. Grisham MB, Hernandez LA, Granger DN. Xanthine oxidase and neutrophil infiltration in intestinal ischemia. Am J Physiol. 1986;251:567-574.
35. Vaux DL. Toward and understanding of the molecular mechanisms of physiological cell death. Proc Natl Acad Sci USA. 1993;90:786-789.
36. Bull DA, Connors RC, Albanil A, et al. Aprotinin preserves myocardial biochemical function during cold storage through suppression of tumor necrosis factor. J Thorac Cardiovasc Surg. 2000;119:242-250.
37. Raff MC. Social controls on cell survival and cell death. Nature. 1992;356:397-400.