Neurotoxic activity of Gln49 phospholipase A2 from Gloydius ussuriensis snake venom

Journal of Applied Toxicology

Volumn 27, Issue 5, 2007, Pages 447-452

  Chang, Yan ^a   Li, Yingxue ^a   Bao, Yongming ^a   An, Lijia ^a  

^a DALIAN UNIVERSITY OF TECHNOLOGY   (China)

Author keywords

Analgesic activity; Gloydius ussuriensis; Hot plate test; Neurotoxin; Phospholipase A2; Snake venom

Indexed keywords

ION CHANNEL; NALOXONE; NEUROTOXIN; OPIATE RECEPTOR; PETHIDINE; PHOSPHOLIPASE A2; SNAKE VENOM;

ACTION POTENTIAL; ANALGESIA; ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; CONTROLLED STUDY; ELECTROPHYSIOLOGY; HOT PLATE TEST; LD 50; MOUSE; NERVE CONDUCTION; NEUROTOXICITY; NONHUMAN; PRIORITY JOURNAL; SCIATIC NERVE; TOAD;

ACTION POTENTIALS; ANIMALS; CROTALID VENOMS; FEMALE; LETHAL DOSE 50; MALE; MICE; NALOXONE; NEURAL CONDUCTION; NEUROTOXINS; PHOSPHOLIPASES A;

BUFO GARGARIZANS; GLOYDIUS USSURIENSIS; MUS;

EID: 34547861651     PISSN: 0260437X     EISSN: 10991263     Source Type: Journal    
DOI: 10.1002/jat.1222     Document Type: Article

References (32)

1. 2: its generation and role in plate activation. Prog. Lipid Res. 28: 273-301.
2. 2 from the venom of Agkistrodon blomhoffii ussurensis. Int. J. Biochem. Cell Biol. 37: 558-565.
3. 2 from Agkistrodon blomhoffii ussurensis snake venom. Progr. Nature Sci. 16: 178-182.
4. + channels. Toxicon 39: 1871-1882.
5. Bonanomi D, Pennuto M, Rigoni M, Rossetto O, Montecucco C, Valtorta F. 2005. Taipoxin induces synaptic vesicle exocytosis and disrupts the interaction of synaptophysin I with VAMP2. Mol. Pharmacol. 67: 1901-1908.
6. 2 isoform: a perspective. Cell. Signal. 15: 637-665.
7. +-ATPase. J. Biol. Chem. 278: 31352-31360.
8. Dijkstra BW, Kalk KH, Hol WGJ, Drenth J. 1981. Structure of bovine pancreatic phospholipase A2 at 1.7 Å resolution. J. Mol. Biol. 147: 97-123.
9. Docherty RJ, Charlesworth G, Farrag K, Bhattacharjee A, Costa S. 2005. The use of the rat isolated vagus nerve for functional measurements of the effect of drugs in vitro. J. Pharmacol. Toxicol. Methods 51: 235-242.
10. Errington AC, Madison K, Kumarc A, Leesa G. 2005. Voltage-gated sodium channels and their roles in drug action. Curr. Anaesth. Crit. Care 16: 81-87.
11. Faure G, Copic A, Le PS, Gubensek F, Bon C, Krizaj I. 2003. Crotoxin acceptor protein isolated from Torpedo electric organ: binding properties to crotoxin by surface plasmon resonance. Toxicon 41: 509-517.
12. 2 isolated from Lachesis muta snake venom comparison with lysophosphatidylcholine. Int. J. Biochem. Cell Biol. 35: 1470-1481.
13. 2 from the venom of Pseudechis Australis, the Australian king Brown snake. Toxicon 30: 1051-1057.
14. 2. Prostaglandins Other Lipid Mediat. 68-69: 71-82.
15. 2, notexin and taipoxin. Exp. Neurol. 161: 517-526.
16. 2 enzymes. Toxicon 42: 827-840.
17. Kocholaty WF, Ledford EB, Daly JG, Billings TA. 1971. Toxicity and some enzymatic properties and activities in venoms of Crotalidae, Elapidae and Viperidae. Toxicon 9: 131-138.
18. 2 and β-neurotoxicity. Biochimie 82: 807-814.
19. Mancin AC, Soares AM, Andriao-Escarso SH, Faca VM, Greene LJ, Zuccolotto S, Pela IR, Giglio JR. 1998. The analgesic activity of crotamine, a neurotoxin from Crotalus Durissus Terrificus (South American Rattlesnake) venom: a biochemical and pharmacological study. Toxicon 36: 1927-1937.
20. Mebs D, Kuch U, Herrmann HW, Ziegler T. 2003. Biochemical and biological activities of the venom of a new species of pitviper from Vietnam, Triceratolepidophis sieversorum. Toxicon 41: 139-143.
21. 2 prevents adenoviral infection in mammalian cells. Biochem. J. 393: 97-106.
22. 2 neurotoxins block nerve terminals. Trends Biochem. Sci. 25: 266-270.
23. 2 homologue from Bothrops asper snake venom induces proliferation, apoptosis and necrosis in a lymphoblastoid cell line. Toxicon 45: 651-660.
24. Prasarnpun S, Walsh J, Harris JB. 2004. Beta-bungarotoxin induced depletion of synaptic vesicles at the mammalian neuromuscular junction. Neuropharmacology 47: 304-314.
25. Pu XC, Wong PTH, Gopalakrishnakone P. 1995. A novel analgesic toxin (hannalgesin) from the venom of king cobra (Ophiophagus Hannah). Toxicon 33: 1425-1431.
26. 2 neurotoxins and lysophospholipid-fatty acid mixtures. Science 310: 1678-1680.
27. 2 Enzymes: Structure, Function and Mechanism, Kini RM (ed.). Wiley: Chichester; 155-183.
28. Rossetto O, Rigoni M, Montecucco C. 2004. Different mechanism of blockade of neuroexocytosis by presynaptic neurotoxins. Toxicol. Lett. 149: 91-101.
29. Sells PG. 2003. Animal experimentation in snake venom research and in vitro alternative. Toxicon 42: 115-133.
30. 2. FEBS Lett. 553: 309-314.
31. Sun RY. 1963. A practical combined method for computing the median lethal dose (LD50). Acta Pharm. Sin. (in Chinese) 10: 65-74.
32. 2. Biochimie 82: 815-831.