Combined effect of solvent content, temperature and pH on the chromatographic behaviour of ionisable compounds

Journal of Chromatography A

Volumn 1163, Issue 1-2, 2007, Pages 49-62

  Pous Torres, S ^a   Torres Lapasio J R ^a   Baeza Baeza, J J ^a   Garcia Alvarez Coque M C ^a  

^a UNIVERSITY OF VALENCIA   (Spain)

Author keywords

Ionisable compounds; Organic solvent; pH; Retention modelling; Reversed phase liquid chromatography; Selectivity; Temperature

Indexed keywords

CATALYST SELECTIVITY; LIQUID CHROMATOGRAPHY; PH EFFECTS;

IONISABLE COMPOUNDS; RETENTION MODELING; REVERSED-PHASE LIQUID CHROMATOGRAPHY;

ORGANIC SOLVENTS;

BENDROFLUMETHIAZIDE; BENZTHIAZIDE; BUMETANIDE; CHEMICAL COMPOUND; CHLORTALIDONE; FUROSEMIDE; OXPRENOLOL; PIRETANIDE; PROBENECID; PROPRANOLOL; SOLVENT; TRICHLORMETHIAZIDE; XIPAMIDE;

ANALYTIC METHOD; ARTICLE; DRUG DETERMINATION; DRUG ISOLATION; IONIZATION; PH MEASUREMENT; PHASE SEPARATION; PRIORITY JOURNAL; REVERSED PHASE HIGH PERFORMANCE LIQUID CHROMATOGRAPHY; SEPARATION TECHNIQUE; TEMPERATURE DEPENDENCE;

ADRENERGIC BETA-ANTAGONISTS; CHROMATOGRAPHY, LIQUID; DIURETICS; HYDROGEN-ION CONCENTRATION; IONS; SOLVENTS; TEMPERATURE;

EID: 34547849617     PISSN: 00219673     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.chroma.2007.06.004     Document Type: Article

References (21)

1. Torres-Lapasió J.R., Baeza-Baeza J.J., and García-Álvarez-Coque M.C. Anal. Chim. Acta 579 (2006) 125
2. Lopes-Marques R.M., and Schoenmakers P.J. J. Chromatogr. 592 (1992) 157
3. Nikitas P., and Pappa-Louisi A. J. Chromatogr. A 971 (2002) 47
4. Ruiz-Ángel M.J., Torres-Lapasió J.R., and García-Álvarez-Coque M.C. J. Chromatogr. A 1022 (2004) 51
5. Dolan J.W. J. Chromatogr. A 965 (2002) 195
6. Li J., and Carr P.W. Anal. Chem. 69 (1997) 837
7. Castells C.B., Cagliardi L.G., Rafols C., Rosés M., and Bosch E. J. Chromatogr. A 1042 (2004) 23
8. Gagliardi L.G., Castells C.B., Ràfols C., Rosés M., and Bosch E. J. Chromatogr. A 1077 (2005) 159
9. Gagliardi L.G., Castells C.B., Ràfols C., Rosés M., and Bosch E. Anal. Chem. 78 (2006) 5858
10. Chloupek R.C., Hancock W.S., Marchylo B.A., Kirkland J.J., Boyes B.E., and Snyder L.R. J. Chromatogr. A 686 (1994) 45
11. Li J. Anal. Chim. Acta 369 (1998) 21
12. Dolan J.W., Snyder L.R., Djordjevic N.M., Hill D.W., and Waeghe T.J. J. Chromatogr. A 857 (1999) 21
13. Wolcott R.G., Dolan J.W., and Snyder L.R. J. Chromatogr. A 869 (2000) 3
14. Dolan J.W., Snyder L.R., Blanc T., and van Heukelem L. J. Chromatogr. A 897 (2000) 37
15. Guillarme D., Heinisch S., and Rocca J.L. J. Chromatogr. A 1052 (2004) 39
16. Espinosa S., Bosch E., and Rosés M. Anal. Chem. 72 (2000) 5193
17. Torres-Lapasió J.R., García-Álvarez-Coque M.C., Rosés M., and Bosch E. J. Chromatogr. A 955 (2002) 19
18. Hansch C.C. In: Sammes y R.G., and Taylor J.B. (Eds). Comprehensive Medicinal Chemistry vol. 6 (1990), Pergamon Press, Oxford
19. Ventura R., and Segura J. J. Chromatogr. B 687 (1996) 127
20. Berthod A., Carda Broch S., and García-Álvarez-Coque M.C. Anal. Chem. 71 (1999) 879
21. Press W.H., Teukolsky S.A., Vetterling W.T., and Flannery B.P. Numerical Recipes in C++: The Art of Scientific Computing. 2nd edition (1992), Cambridge University Press, New York