Leptin protects vital organ functions after sepsis through recovering tissue myeloperoxidase activity: An anti-inflammatory role resonating with indomethacin

Peptides

Volumn 28, Issue 8, 2007, Pages 1553-1560

  Lin, Ji ^a   Yan, Guang Tao ^a   Xue, Hui ^a   Hao, Xiu Hua ^a   Zhang, Kai ^a   Wang, Lu Huan ^a  

^a GENERAL HOSPITAL OF NORTHERN THEATER COMMAND   (China)

Author keywords

Indomethacin; Leptin; Myeloperoxidase; Recovery of function; Sepsis

Indexed keywords

ALANINE AMINOTRANSFERASE; INDOMETACIN; LEPTIN; MYELOPEROXIDASE; URIC ACID;

ALANINE AMINOTRANSFERASE BLOOD LEVEL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ANTIINFLAMMATORY ACTIVITY; ARTICLE; CONTROLLED STUDY; ENZYME ACTIVITY; ENZYME BLOOD LEVEL; HEART; HORMONE BLOOD LEVEL; IMMUNOHISTOCHEMISTRY; KIDNEY; LIVER; LUNG; MOUSE; NONHUMAN; PRIORITY JOURNAL; SEPSIS; STATISTICAL SIGNIFICANCE; URIC ACID BLOOD LEVEL;

ALANINE TRANSAMINASE; ANIMALS; ANTI-INFLAMMATORY AGENTS, NON-STEROIDAL; INDOMETHACIN; KIDNEY; LEPTIN; LIVER; LUNG; MICE; MICE, INBRED C57BL; MODELS, BIOLOGICAL; NEUROIMMUNOMODULATION; PEROXIDASE; SEPSIS; URIC ACID;

MUS;

EID: 34547845335     PISSN: 01969781     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.peptides.2007.06.024     Document Type: Article

References (29)

1. Anderson F.L., Jubiz W., Tsagaris T.J., and Kuida H. Endotoxin-induced prostaglandin E and F release in dogs. Am J Physiol 228 (1975) 410-414
2. Arnhold J. Properties, functions, and secretion of human myeloperoxidase. Biochem Mosc 69 (2004) 4-9
3. Bekesi G., Heinle H., Kakucs R., Pazmany T., Szombath D., Dinya M., et al. Effect of inhibitors of myeloperoxidase on the development of aortic atherosclerosis in an animal model. Exp Gerontol 40 (2005) 199-208
4. Bradford M.M. A rapid and sensitive method for the quantitation of microgram quantities of protein utilizing the principle of protein-dye binding. Anal Biochem 72 (1976) 248-254
5. Caldefie-Chezet F., Poulin A., and Vasson M.P. Leptin regulates functional capacities of polymorphonuclear neutrophils. Free Radic Res 37 (2003) 809-814
6. Corral J., Yelamos J., Hernandez-Espinosa D., Monreal Y., Mota R., Arcas I., et al. Role of lipopolysaccharide and cecal ligation and puncture on blood coagulation and inflammation in sensitive and resistant mice models. Am J Pathol 166 (2005) 1089-1098
7. Crawford J.H., Yang S., Zhou M., Simms H.H., and Wang P. Down-regulation of hepatic CYP1A2 plays an important role in inflammatory responses in sepsis. Crit Care Med 32 (2004) 502-508
8. Fruhbeck G. Intracellular signalling pathways activated by leptin. Biochem J 393 (2006) 7-20
9. Hansson M., Olsson I., and Nauseef W.M. Biosynthesis, processing, and sorting of human myeloperoxidase. Arch Biochem Biophys 445 (2006) 214-224
10. Hosoi T., Okuma Y., Wada S., and Nomura Y. Inhibition of leptin-induced IL-1beta expression by glucocorticoids in the brain. Brain Res 969 (2003) 95-101
11. Jacobs E.R., Soulsby M.E., Bone R.C., Wilson Jr. F.J., and Hiller F.C. Ibuprofen in canine endotoxin shock. J Clin Invest 70 (1982) 536-541
12. Jaworek J., Bonior J., Pierzchalski P., Tomaszewska R., Stachura J., Sendur R., et al. Leptin protects the pancreas from damage induced by caerulein overstimulation by modulating cytokine production. Pancreatology 2 (2002) 89-99
13. Kazumi T., Kawaguchi A., Hirano T., and Yoshino G. C-reactive protein in young, apparently healthy men associations with serum leptin, QTc interval, and high-density lipoprotein-cholesterol. Metab Clin Exp 52 (2003) 1113-1116
14. Kessler E., Hughes R.C., Bennett E.N., and Nadela S.M. Evidence for the presence of prostaglandin-like material in the plasma of dogs with endotoxin shock. J Lab Clin Med 81 (1973) 85-94
15. Leininger M.T., Portocarrero C.P., Bidwell C.A., Spurlock M.E., and Houseknecht K.L. Leptin expression is reduced with acute endotoxemia in the pig: correlation with glucose, insulin, and insulin-like growth factor-1 (IGF-1). J Interferon Cytokine Res 20 (2000) 99-106
16. Madiehe A.M., Mitchell T.D., and Harris R.B. Hyperleptinemia and reduced TNF-alpha secretion cause resistance of db/db mice to endotoxin. Am J Physiol Regul Integr Comp Physiol 284 (2003) R763-R770
17. Marikovsky M., Rosenblum C.I., Faltin Z., and Friedman-Einat M. Appearance of leptin in wound fluid as a response to injury. Wound Repair Regen 10 (2002) 302-307
18. Martin-Romero C., Santos-Alvarez J., Goberna R., and Sanchez-Margalet V. Human leptin enhances activation and proliferation of human circulating T lymphocytes. Cell Immunol 199 (2000) 15-24
19. Moshyedi A.K., Josephs M.D., Abdalla E.K., Mackay S.L., Edwards C.K., Copeland E.M., et al. Increased leptin expression in mice with bacterial peritonitis is partially regulated by tumor necrosis factor alpha. Infect Immun 66 (1998) 1800-1802
20. Najib S., and Sanchez-Margalet V. Human leptin promotes survival of human circulating blood monocytes prone to apoptosis by activation of p42/44 MAPK pathway. Cell Immunol 220 (2002) 143-149
21. Palacio A., Lopez M., Perez-Bravo F., Monkeberg F., and Schlesinger L. Leptin levels are associated with immune response in malnourished infants. J Clin Endocrinol Metab 87 (2002) 3040-3046
22. Reddy R.C., Chen G.H., Tateda K., Tsai W.C., Phare S.M., Mancuso P., et al. Selective inhibition of COX-2 improves early survival in murine endotoxemia but not in bacterial peritonitis. Am J Physiol Lung Cell Mol Physiol 281 (2001) L537-L543
23. Remick D.G., Bolgos G.R., Siddiqui J., Shin J., and Nemzek J.A. Six at six: interleukin-6 measured 6 h after the initiation of sepsis predicts mortality over 3 days. Shock 17 (2002) 463-467
24. - system of neutrophils by indomethacin and other non-steroidal anti-inflammatory drugs. Biochem Pharmacol 41 (1991) 975-984
25. Takahashi N., Waelput W., and Guisez Y. Leptin is an endogenous protective protein against the toxicity exerted by tumor necrosis factor. J Exp Med 189 (1999) 207-212
26. Theron C.N., Lubbe S., and Van Zyl A. Inhibitory effects of non-steroidal anti-inflammatory drugs on human myeloperoxidase. S Afr Med J 56 (1979) 670-675
27. Waelput W., Brouckaert P., Broekaert D., and Tavernier J. A role for leptin in the systemic inflammatory response syndrome (SIRS) and in immune response, an update. Curr Med Chem 13 (2006) 465-475
28. Wallace A.M., Tucker P., Williams D.M., Hughes I.A., and Ahmed S.F. Short-term effects of prednisolone and dexamethasone on circulating concentrations of leptin and sex hormone-binding globulin in children being treated for acute lymphoblastic leukaemia. Clin Endocrinol (Oxf) 58 (2003) 770-776
29. Zerani M., Boiti C., Dall'Aglio C., Pascucci L., Maranesi M., Brecchia G., et al. Leptin receptor expression and in vitro leptin actions on prostaglandin release and nitric oxide synthase activity in the rabbit oviduct. J Endocrinol 185 (2005) 319-325