Semiparametric functional mapping of quantitative trait loci governing long-term HIV dynamics

Bioinformatics

Volumn 23, Issue 13, 2007, Pages

  Wu, Song ^a   Yang, Jie ^a   Wu, Rongling ^a  

^a University of Florida ^*  (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ACQUIRED IMMUNE DEFICIENCY SYNDROME; CONFERENCE PAPER; CONTROLLED STUDY; DISEASE COURSE; GENE MAPPING; GENETIC ANALYSIS; GENETIC REGULATION; GENETIC TRAIT; HUMAN IMMUNODEFICIENCY VIRUS; HUMAN IMMUNODEFICIENCY VIRUS INFECTION; MATHEMATICAL COMPUTING; MATHEMATICAL MODEL; MAXIMUM LIKELIHOOD METHOD; MONTE CARLO METHOD; PATHOPHYSIOLOGY; PRIORITY JOURNAL; PROCESS MODEL; QUANTITATIVE TRAIT LOCUS MAPPING; STATISTICAL ANALYSIS; STATISTICAL MODEL; VIRUS CELL INTERACTION; VIRUS LOAD;

HUMAN IMMUNODEFICIENCY VIRUS;

EID: 34547844101     PISSN: 13674803     EISSN: 13674811     Source Type: Journal    
DOI: 10.1093/bioinformatics/btm164     Document Type: Conference Paper

References (16)

1. Bartels, R.H. et al. (1987) An Introduction to Splines for Use in Computer Graphics and Geometric Modelling. Morgan Kaufmann, Morgan Kaufmann Publishers, San Francisco, CA.
2. Ho, D.D. et al. (1995) Rapid turnover of plasma virions and CD4 lymphocytes in HIV-1 infection. Nature, 373, 123-126.
3. Knott, G.D. (1999) Interpolating Cubic Splines. Birkhäuser, Boston, MA.
4. Lander, E.S. and Botstein, D. (1989) Mapping Mendelian factors underlying quantitative traits using RFLP linkage maps. Genetics, 121, 185-199.
5. Ma, C.X. et al. (2002) Functional mapping of quantitative trait loci underlying the character process: A theoretical framework. Genetics, 161, 1751-1762.
6. O'Brien, S.J. and Nelson, G.W. (2004) Human genes that limit AIDS. Nat. Genet., 13, 565-574.
7. Perelson, A.S. et al. (1997) Decay characteristics of HIV-1-infected compartments during combination therapy. Nature, 387, 188-191.
8. Wang, Z.H. and Wu, R.L. (2004) A statistical model for high-resolution mapping of quantitative trait loci determining HIV dynamics. Stat. Med, 23, 3033-3051.
9. Wang, Z.H. et al. (2005) A statistical model to analyze quantitative trait locus interactions for HIV dynamics from the virus and human genomes. Stat. Med, 25, 495-511.
10. Wu, H. and Ding, A. (1999) Population HIV-1 dynamics in vivo: Applicable models and inferential tools for virological data from AIDS clinical trials. Biometrics, 55, 410-418.
11. Wu, H. and Zhang, J.T. (2002) The study of long-term HIV dynamics using scmiparametric nonlinear mixed-effects models. Stat. Med., 21 3655-3675.
12. Wu, R.L. and Lin, M. (2006) Functional mapping - how to map and study the genetic architecture of dynamic complex traits. Nat. Rev. Genet 7, 229-237.
13. Wu, R.L. (2004) Functional mapping of growth quantitative trait loci using a transform-both-sides logistic model. Biometrics, 60, 729-738.
14. Wu, S. (2006) Multilocus linkage disequilibrium mapping of epistatic quantitative trait loci that regulate HIV dynamics: A simulation approach. Stat, Med., 25, 3826-3849.
15. Zhao, W. et al. (2004) A fast algorithm for functional mapping of complex traits. Genetics, 167, 2133-2137.
16. Zhao, W. et al. (2005) A nonstationary model for functional mapping of complex traits. Bioinformatics, 21, 2469-2477.