The clinical significance of IGF-I in maternal serum during pregnancy in type 1 diabetes

Current Diabetes Reviews

Volumn 3, Issue 3, 2007, Pages 194-197

  Lauszus, Finn Friis ^a  

^a HERNING HOSPITAL   (Denmark)

Author keywords

Birth weight; Diabetes mellitus; FGF 2; IGF I; IGF II; IGFBP 1; IGFBP 3; Retinopathy

Indexed keywords

FIBROBLAST GROWTH FACTOR 2; HEMOGLOBIN A1C; INSULIN DERIVATIVE; ISOPROTEIN; PLACENTAL GROWTH FACTOR; PREGNANCY ASSOCIATED PLASMA PROTEIN A; SOMATOMEDIN B; SOMATOMEDIN BINDING PROTEIN; SOMATOMEDIN C;

ALBUMINURIA; BIRTH WEIGHT; CORRELATION ANALYSIS; DIABETIC RETINOPATHY; DISEASE COURSE; FETUS ECHOGRAPHY; FETUS GROWTH; GESTATIONAL AGE; GLYCEMIC CONTROL; HORMONE ACTION; HUMAN; INSULIN DEPENDENT DIABETES MELLITUS; INTRAUTERINE GROWTH RETARDATION; MACROSOMIA; MULTIPLE PREGNANCY; ONSET AGE; PREGNANCY DIABETES MELLITUS; PRIORITY JOURNAL; PROTEIN BLOOD LEVEL; PROTEIN DEGRADATION; PROTEIN DETERMINATION; PROTEIN FUNCTION; PROTEIN PHOSPHORYLATION; PROTEIN PROTEIN INTERACTION; PROTEIN SYNTHESIS; REGULATORY MECHANISM; REVIEW; RISK ASSESSMENT; THIRD TRIMESTER PREGNANCY;

BIOLOGICAL MARKERS; BIRTH WEIGHT; DIABETIC RETINOPATHY; FEMALE; HUMANS; INFANT, NEWBORN; INSULIN-LIKE GROWTH FACTOR I; MOTHERS; PREGNANCY; PREGNANCY IN DIABETICS;

EID: 34547841326     PISSN: 15733998     EISSN: None     Source Type: Journal    
DOI: 10.2174/157339907781368922     Document Type: Review

References (51)

1. Barker DJ. Programming the baby. In: Mothers, babies and health in later life. Glasgow, Churchill Livingstone. 1998; 13-41.
2. Bereket A, Lang CH, Blethen SL, Fan J, Frost RA, Wilson TA. Effect of insulin on IGF system in children with new onset IDDM. J Clin Endocrinol Metab 1995; 80: 1312-7.
3. Simmons D. Interrelation between umbilical cord serum sex hormones, sex hormone-binding globulin, IGF-I, and insulin in neonates from normal pregnancies and pregnancies complicated by diabetes. J Clin Endocrinol Metab 1995; 80: 2217-21.
4. Pedersen J. The pregnant diabetic and her newborn. 2nd edition. Copenhagen, Munksgaard, Denmark. 1977; 211-21.
5. Delmis J, Drazancic A, Ivanisevic M, Suchanek E. Glucose, insulin, hGH, and IGF-I levels in maternal serum, amniotic fluid and umbilical serum: a comparison between late normal pregnancy and pregnancies complicated with diabetes and fetal growth retardation. J Perinat Med 1992; 20: 47-56.
6. Reece EA, Wiznitzer A, Le E, Homko CJ, Behrmann H, Spencer EM. The relation between human fetal growth and fetal blood levels of IGF-I and -II, their binding proteins, and receptors. Obstet Gynecol 1994; 84: 88-95.
7. Giudice LC, Martina NA, Crystal RA, Tazuke S, Druzin M. Insulin-like growth factor binding protein-1 at the maternal-fetal interface and insulin-like growth factor-I, insulin-like growth factor-II, and insulin-like growth factor binding protein-1 in the circulation of women with severe pre-eclampsia. Am J Obstet Gynecol 1997; 176: 751-758.
8. Kajantie E, Dunkel L, Rutanen EM, et al. IGF-I, IGFBP-3, phosphoisoforms of IGFBP-1, and postnatal growth in very low birth weight infants. J Clin Endocrinol Metab 2002; 87: 2171-9.
9. Holly JMP, Martin JL. Insillin-like growth factor binding proteins: a review a methodological aspects of their purification, analysis, and regulation. Growth Regal 1993; 4: 20-30.
10. Gibson JM, Westwood M, Lauszas FF, Klebe JG, Flyvbjerg A, White A. Phosphorylated insulin-like growth factor-binding protein 1 is increased in pregnant diabetic subjects. Diabetes 1999; 48: 321-6.
11. Westwood M, Gibson JM, Davies AJ, Young RJ, White A. The phosphorylation pattern of insulin-like growth factor-binding protein-1 in normal plasma is different from that in amniotic fluid and changes during pregnancy. J Clin Endocrinol Metab 1994; 79: 1735-41.
12. Lawrence JB, Oxvig C, Overgaard MT, et al. The insulin-like growth factor (IGF)-dependent IGF binding protein-4 protease secreted by human fibroblasts is pregnancy-associated plasma protein-A. Proc Natl Acad Sci U S A 1999; 96: 3149-53.
13. Pedersen JF, Sorensen S, Molsted-Pedersen L. Serum levels of human placental lactogen, pregnancy-associated plasma protein A and endometrial secretory protein PP14 in first trimester of diabetic pregnancy. Acta Obstet Gynecol Scand 1998; 77: 155-8.
14. Pedersen JF, Sorensen S, Ruge S. Human placental lactogen and pregnancy-associated plasma protein A in first trimester and subsequent fetal growth. Acta Obstet Gynecol Scand 1995; 74: 505-8.
15. Hill WC, Pelle-Day G, Kitzmiller JL, Spencer EM. IGFs in fetal macrosomia with and without maternal diabetes. Horm Res 1989; 32: 178-82.
16. Iwashita M, Kobayashi M, Matsuo A, et al. Feto-maternal interaction of IGF-I and its binding proteins in fetal growth. Early Hum Dev 1992; 29: 187-91.
17. Wang HS, Chard T. The role of IGF-I and IGFBP-1 in the control of human fetal growth. J Endocrinol 1992; 132: 11-9.
18. Damm P, Molsted-Pedersen L. Significant decrease in congenital malformations in newborn infants of an unselected population of diabetic women. Am J Obstet Gynecol 1989; 161: 1163-7.
19. Espersen T, Klebe JG. Self-monitoring of blood glucose in pregnant diabetics. A comparative study of the blood glucose level and course of pregnancy in pregnant diabetics on an out-patient regime before and after the introduction of methods for home analysis of blood glucose. Acta Obstet Gynecol Scand 1985; 64: 11-4.
20. Lauszus FF. Klebe JG, Flyvbjerg A. A prospective study of the association between maternal serum insulin-like growth factor I and -II in diabetic pregnancy and macrosomia. Obstet Gynecol 2001; 97: 734-41.
21. Lauszus FF, Klebe JG, Bek T, Flyvbjerg A. Increased serum IGF-I during pregnancy is associated with progression of diabetic retinopathy. Diabetes 2003; 52: 852-6.
22. Langford KS, Nicolaides KH, Jones J, Abbas A, McGregor AM, Miell JP. Serum IGFBP-3 levels and IGFBP-3 protease activity in normal, abnormal, and multiple pregnancy. J Clin Endocrinol Metab 1995; 80: 21-7.
23. Caufriez A, Frankenne F, Hennen G, Copinschi G. Regulation of maternal IGF-I by placental growth hormone in pregnancy. Possible action of maternal IGF-I on fetal growth. Horm Res 1994; 42: 62-5.
24. Holmes RP, Holly JM, Soothill PW. A prospective study of maternal serum insulin-like growth factor I in pregnancies with appropriately grown or growth restricted fetuses. Br J Obstet Gynaecol 1998; 105: 1273-8.
25. Whittaker PG, Stewart MO, Taylor A, Howell RJ, Lind T. Insulin-like growth factor 1 and its binding protein 1 during normal and diabetic pregnancies. Obstet Gynecol 1990; 76: 223-9.
26. Fuglsang J, Lauazus F, Flyvbjerg A, Ovesen P. Human placental growth hormone, insulin-like growth factor I and -II, and insulin requirements during pregnancy in type 1 diabetes. J Clin Endocrinol Metab 2003; 88: 4355-61.
27. Di Biase N, Napoli A, Caiola S, et al. IGF-1 levels in diabetic pregnant women and their infants. Ann Ist Super Sanita 1997; 33: 379-82.
28. Pedersen JF, Juul A, Molsted-Pedersen L, Skakkeback NE. Serum levels of insulin-like growth factor-1 in first trimester of diabetic pregnancy: relation to early growth delay. Br J Obstet Gynaecol 1995; 102: 927-8.
29. Kubota T, Kamada S, Taguchi M, Aso T. Determination of IGF-II in feto-maternal circulation during human pregnancy. Acta Endocrinol (Copenh) 1992; 127: 359-65.
30. McIntyre HD; Serek R, Crane DI, et al. Placental growth hormone (GH), GH-binding protein, and insulin-like growth factor axis in normal, growth-retarded, and diabetic pregnancies: correlations with fetal growth. J Clin Endocrinol Metab 2000; 85: 1143-50.
31. Wang HS, Lee JD, Soong YK. Serum levels of insulin-like growth factor I and insulin-like growth factor-binding protein-1 and -3 in women with regular menstrual cycles. Fertil Steril 1995; 63: 1204-9.
32. Mirlesse V, Frankenne F, Alsat E, Poncelet M, Hennen G, Evain-Brion D. Placental growth hormone levels in normal pregnancy and in pregnancies with intrauterine growth retardation. Pediatr Res 1993; 34: 439-42.
33. Caufriez A, Frankenne F, Hennen G, Copinschi G. Regulation of maternal IGF-I by placental GH in normal and abnormal human pregnancies. Am J Physiol 1993; 265(4 Pt 1): E572-7.
34. Suikkari AM, Koivisto VA, Rutanen EM, Yki-Jarvinen H, Karonen SL, Seppala M. Insulin regulates the serum levels of low molecular weight insulin-like growth factor-binding protein. J Clin Endocrinol Metab 1988; 66: 266-72.
35. Gibson JM, Aplin JD, White A, Westwood M. Regulation of IGF bioavailability in pregnancy. Mol Hum Reprod 2001; 7: 79-87.
36. Hossenlopp P, Segovia B, Lassarre C, Roghani M, Bredon M, Binoux M. Evidence of enzymatic degradation of insulin-like growth factor-binding proteins in the 150K complex during pregnancy. J Clin Endocrinol Metab 1990; 71: 797-805.
37. Giudice LC, Farrell EM, Pham H, Lamson G, Rosenfeld RG. Insulin-like growth factor binding proteins in maternal serum throughout gestation and in the puerperium: effects of a pregnancy-associated serum protease activity. J Clin Endocrinol Metab 1990; 71: 806-16.
38. Lundbæk K, Christensen NJ, Jensen VA, et al. Diabetes, diabetic angiopathy and growth hormone. Lancet 1970; 2(7664): 131-133.
39. Pfeiffer A, Spranger J, Meyer-Schwickerath R, Schatz H. Growth factor alterations in advanced diabetic retinopathy: a possible role of blood retina barrier breakdown. Diabetes. 1997; 46 (Suppl 2): S26-30.
40. Merrimee TJ, Zapf J, Froesch R. Insulin-like growth factors. Studies in diabetics with and without retinopathy. N Eng J Med 1983; 309: 527-530.
41. Grant M, Russell B, Fitzgerald C, Merrimee TJ. Insulin-like growth factors in vitreous. Studies in control and diabetic subjects with neovascularization. Diabetes 1986; 35: 416-420.
42. DCCT/EDIC. Retinopathy and nephropathy in patients with type 1 diabetes four years after a trial of intensive treatment. N Eng J Med 2000; 342: 381-9.
43. Temple RC, Alridge, VA, Sampson MJ, Greenwood RH, Heyburn PJ, Glenn A. Impact of pregnangy on the progression of diabetic retinopathy in type 1 diabetes. Diabet Med 2001; 18: 573-77.
44. Hyer SL, Sharp PS, Sleightholm M, Burrirr JM, Kohner EM. Progression of diabetic retinopathy and changes in serum IGF-1 during continous subcutaneous insulin infusion. Horm Metab Res 1989; 21: 18-22.
45. Chantalau E, Evidence that upregulation of serum IGF-1 concentration can trigger acceleration of dibetic retinopathy. Br J Ophthalmol 1998; 82: 725-730.
46. Feldmann B, Lang GE, Arnavaz A, Jehle PM, Böhm BO, Lang GK. Lower concentration of bioavailable IGF-1 in patients with diabetic retinopathy. (Verminderte Serumspiegel von freiem bioverfügbarem IGF-1 bei Patienten mit diabetischer Retinopathie.) In German. Ophthalmologe 1999; 96: 300-305.
47. Janssen JAMJL, Jacobs ML, Derkx FHM, Weber RFA, Van der Lely AJ, Lamberts SW. Free and total IGF-1, IGFBP-1, and IGFBP-3 and their relationships to the presence of diabetic retinopathy and glomerular hyperfiltration in insulin-dependent diabetes mellitus. J Clin Endocrinol Metab 1997; 82: 2809-2815.
48. Wang Q, Dills DG, Klein R, Klein BEK, Moss SE. Does IGF-1 predict incidence and progression of diabetic retinopathy? Diabetes 1995; 44: 161-164.
49. Hill DJ, Flyvbjerg A, Arany E, Lauszus FF, Klebe JG. Increased levels of serum fibroblast growth factor-2 (FGF-2) in diabetic pregnant women with retinopathy. J Clin Endocrinol Metab 1997; 82: 1452-57.
50. Frystyk J, Bek T, Flyvbjerg A, Skjaerback C, Orskov H. The relationship between the circulating IGF system and the presence of retinopathy in Type 1 diabetic patients. Diabet Med 2003; 20: 269-76.
51. Burgos R, Mateo C, Canton A, Hernandez C, Mesa J, Simo R. Vitreous levels of IGF-I, IGFBP-1, and IGFBP-3 in proliferative diabetic retinopathy: a case-control study. Diabetes Care 2000; 23: 80-3.