The use of the bone seeking radiopharmaceutical 153-samarium-EDTMP as an adjuvant treatment for osteosarcoma: A review

Current Medical Imaging Reviews

Volumn 3, Issue 3, 2007, Pages 214-218

  Essman, Stephanie C ^a  

^a UNIVERSITY OF MISSOURI   (United States)

Author keywords

Juvenile; Osteosarcoma; Physeal cartilage; Samarium

Indexed keywords

ANALGESIC AGENT; ANTINEOPLASTIC AGENT; LEXIDRONAM SAMARIUM SM 153; MEDRONATE TECHNETIUM TC 99M; OXIDRONATE TECHNETIUM TC 99M; PLACEBO;

AMPUTATION; ANTINEOPLASTIC ACTIVITY; BONE GROWTH; BONE MARROW TOXICITY; BONE METASTASIS; BONE PAIN; CANCER ADJUVANT THERAPY; CANCER SURVIVAL; CLINICAL TRIAL; DOSE RESPONSE; DRUG ABSORPTION; DRUG DISTRIBUTION; DRUG DOSE COMPARISON; DRUG EFFICACY; DRUG MEGADOSE; EXTERNAL BEAM RADIOTHERAPY; HUMAN; LEUKOPENIA; LOW DRUG DOSE; MAXILLA RESECTION; MULTIMODALITY CANCER THERAPY; NONHUMAN; OSTEOSARCOMA; PANCYTOPENIA; PRIORITY JOURNAL; QUALITY OF LIFE; RADIOISOTOPE THERAPY; REVIEW; SINGLE DRUG DOSE; THROMBOCYTOPENIA;

EID: 34547841311     PISSN: 15734056     EISSN: None     Source Type: Journal    
DOI: 10.2174/157340507781387013     Document Type: Review

References (35)

1. Gaitan-Yanguas M. A study of the response of osteogenic sarcoma and adjacent normal tissue to radiation. Int J Radiat Oncol Biol Phys 1981; 7: 593-595.
2. Lattimer JC, Corwin LA, Stapleton J, et al. Clinical and clinicopathologic response of canine bone tumor patients to treatment with samarium-153-EDTMP. J Nuc Med 1990; 31; 1316-1325.
3. 153Sm-EDTMP. J Ped Oncol Nurs 1998; 15: 95-97.
4. Goeckeler WF, Edwards B, Volkert WA, Holmes RA, Simon J, Wilson D. Skeletal localization of samarium-153 chelates: Potentional therapeutic bone agents. J Nuc Med 1987; 28: 495-504.
5. 153Sm]EDTMP: A potential therapy for bone cancer pain. Sem Nuc Med 1992; 22: 41-45.
6. Turner JH, Martindale AA, Sorby P, et al. Samarium-153 EDTMP therapy of disseminated skeletal metastasis. Eur J Nucl Med 1989; 15: 784-795.
7. Serafini AN, Houston SJ, Resche I, et al. Palliation of pain associated with metastatic bone cancer using samarium-153 lexidronam: A double-blind placebo-controlled clinical trial. J Clin Oncol 1998; 16: 1574-1581.
8. Bayouth JE, Macey DJ, Kasi LP, Fossella FV. Dosimetry and toxicity of samarium-153-EDTMP administered for bone pain due to skeletal metastases. J Nucl Med 1994; 35: 63-69.
9. Ben-Josef E, Porter AT. Radioisotopes in the treatment of bone metastases. Ann Med 1997; 29: 31-35.
10. Resche I, Chatal JF, Pecking A, et al. A dose-controlled study of Sm-153-EDTMP in the treatment of patients with painful bone metastases. Eur J Cancer 1997; 33: 1583-1591.
11. 153Sm-EDTMP. Clin cancer Res 1999; 5: 3148s-3152s.
12. Franzius C, Bielack S, Sciuk J, Vollet B, Jurgens H, Schober O. High-activity samarium-153- EDTMP therapy in unresectable osteosarcoma. Nuklearmedizin 1999; 38: 337-340.
13. Franzius C, Bielack S, Flege S, Eckardt J, et al. High-activity Samarium-153-EDTMP therapy followed by autologous peripheral blood stem cell support in unresectable osteosarcoma. Nuklearmedizin 2001; 40: 215-220.
14. 153Sm-EDTMP in recurrent canine osteosarcoma. J Small Animal Pract 1996; 37: 241-246.
15. Anderson PM, Wiseman GA, Dispenzieri A, et al. High dose samarium-153 ethylene diamine tetramethylene phosphonate: Low toxicity of skeletal irradiation in patients with osteosarcoma and bone metastases. J Clin Oncol 2002; 20: 189-196.
16. 153Sm-EDTMP. Acta Oncol 1996; 35: 381-384.
17. Milner RJ, Dormehl I, Louw WKA, Croft S. Targeted radiotherapy with Sm-153-EDTMP in nine cases of canine primary bone tumors. S Afr Vet J 1998; 69: 12-17.
18. Anderson P. Samarium for osteoblastic bone metastases and osteosarcoma. Expert Opin Pharmacother 2006; 7(11): 1475-1486.
19. Eifel PJ, Donaldson SS, Thomas PF. Response of growing bone to irradiation: A proposed late effects scoring system. Int J Radiation Oncology Biol Phys 1995; 31: 1301-1307.
20. Melanotte PL, Follis RH. Early effects of x-irradiation on cartilage and bone. Am J Path 1961; 39: 1-7.
21. Rutherford H, Dodd GD. Complications of radiation therapy: Growing bone. Sem Roentgenol 1974; 7:15-26.
22. Probert JC, Parker BR. The effects of radiation therapy on bone growth. Radiology 1975; 114: 155-162.
23. Parker RG, Berry HC. Late effects of therapeutic irradiation on the skeleton and bone marrow. Cancer 1976; 37: 1162-1171.
24. Gonzalez DG, Breur K. Clinical data from irradiated growing long bones in children. Int J Radiat Oncol Biol Phys 1983; 9: 841-846.
25. Rubin P, Andrews R, Swarm R, Gump H. Radiation induced dysplasias of bone. Am J Roent Rad Ther 1959; 82a: 206-215.
26. Hinkel CL. The effect of roentgen rays upon the growing long bones of albino rats: histopathological changes involving endochondral growth centers. Am J Roent Rad Ther 1943; 49: 321-348.
27. Hall EJ. Radiobiology for the radiologist. 5th ed. 343-344. Philedelphia, Pennsylvania: J. B. Lippincott Company; 1994.
28. Frantz CH. Extreme retardation of epiphyseal growth from roentgen irradiation. Radiology 1950; 55: 720-724.
29. Gonzalez DG, Van Dijk DP. Experimental studies on the response of growing bones to x ray and neutron irradiation. Int J Radiat Oncol Biol Phys 1983; 9: 671-677.
30. 153Sm-EDTMP on physeal and articular cartilage in juvenile rabbits. J Nucl Med 2003; 44: 1510-1515.
31. Alini M, Carey D, Hirata S, Grynpas MD, Pidoux I, Poole AR. Cellular and matrix changes before and at the time of calcification in the growth plate studied in vitro: Arrest of type X collagen synthesis and net loss of collagen when calcification in initiated. J Bone Miner Res 1994; 9: 1077-1086.
32. Schmid TM, Linsenmayer TF. Immunohistochemical localization of short chain cartilage collagen (type X) in avian tissues. J Cell Biol 1985; 100: 598-605.
33. D'Angelo M, Yan Z, Nooreyazdan M, et al. MMP-13 is induced during chondrocytes hypertrophy. J Cell Biochem 2000; 77: 678-693.
34. 153Sm-EDTMP in the juvenile rabbit tibia: Implications for targeted radiotherapy of osteosarcoma. J Nucl Med 2005; 46: 2076-2082.
35. Briesmeister JE. MCNP - A general Monte Carlo N-particle transport code, version 4C, report LA-13709-M. Los Alamos National Laboratory 2000.