Use of the cytosensor microphysiometer to predict results of a 21-day cumulative irritation patch test in humans

Toxicology in Vitro

Volumn 21, Issue 6, 2007, Pages 1165-1173

  Landin, Wendell E ^a   Mun, Greg C ^b   Nims, Raymond W ^c   Harbell, John W ^b  

^a KIMBERLY CLARK CORPORATION   (United States)

^b Institute for in Vitro Sciences   (United States)

^c BioReliance Invitrogen Bioservices   (United States)

Author keywords

21 Day cumulative irritation patch test; Cumulative irritation; Cytosensor ; In vitro; Microphysiometer

Indexed keywords

BUFFER; IRRITANT AGENT; SURFACTANT;

ACIDIFICATION; ACUTE TOXICITY; ANALYTICAL EQUIPMENT; ANIMAL CELL; ARTICLE; CELL METABOLISM; CHRONIC TOXICITY; COMPARATIVE STUDY; CONCENTRATION (PARAMETERS); CONTROLLED STUDY; CYTOTOXICITY; EPIDERMIS CELL; HYGIENE; METABOLIC RATE; MICROPHYSIOMETER; MODEL; MOUSE; NONHUMAN; PATCH TEST; PREDICTION; PRODUCT DEVELOPMENT; SAMPLE; SCORING SYSTEM; SCREENING TEST; SENSITIVITY ANALYSIS; SKIN IRRITATION; SKIN PENETRATION; SKIN TEST; STRATUM CORNEUM;

ANIMAL TESTING ALTERNATIVES; ANIMALS; CELL LINE; CONSUMER PRODUCT SAFETY; COSMETICS; DERMATITIS, IRRITANT; HUMANS; MICE; PATCH TESTS; REPRODUCIBILITY OF RESULTS; SENSITIVITY AND SPECIFICITY; SKIN IRRITANCY TESTS; SURFACE-ACTIVE AGENTS;

ANIMALIA;

EID: 34547813078     PISSN: 08872333     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.tiv.2007.03.006     Document Type: Article

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