Synthetic studies on (-)-FR182877: construction of the ABCD ring system via the intramolecular cycloadditions (2)

Tetrahedron Letters

Volumn 48, Issue 37, 2007, Pages 6488-6492

  Tanaka, Natsumi ^a   Suzuki, Takahiro ^a   Hosoya, Yosuke ^a   Nakada, Masahisa ^a  

^a WASEDA UNIVERSITY   (Japan)

Author keywords

[No Author keywords available]

Indexed keywords

ALKADIENE; ALKANE DERIVATIVE; ANTINEOPLASTIC AGENT; FR 182877; UNCLASSIFIED DRUG;

ARTICLE; CYCLOADDITION; DIASTEREOISOMER; DIELS ALDER REACTION; DRUG SYNTHESIS; GEOMETRY; HORNER WADSWORTH EMMONS REACTION; HYDROLYSIS; MOLECULAR DYNAMICS; NUCLEAR OVERHAUSER EFFECT; STEREOCHEMISTRY;

ALNUS;

EID: 34547797912     PISSN: 00404039     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.tetlet.2007.07.052     Document Type: Article

References (9)

1. Suzuki T., Tanaka N., Matsumura T., Hosoya Y., and Nakada M. Tetrahedron Lett. 48 (2007) 10.1016/j.tetlet.2007.07.051
2. Suffert J., and Toussaint D. Tetrahedron Lett. 38 (1997) 5507-5510
3. The low yield could arise from formation of the structurally unidentified polar side-products.
4. 3).
5. Braun N.A., Klein I., Spitzner D., Vogler B., Braun S., Borrmann H., and Simon A. Liebigs Ann. (1995) 2165-2169
6. Braun N.A., Bürkle U., Feth M.P., Klein I., and Spitzner D. Eur. J. Org. Chem. (1998) 1569-1576
7. The yield was not optimized.
8. 3).
9. The substituents in the transition state models are omitted for clarity.