Characterization of humanized liver from chimeric mice using coumarin as a human CYP2A6 and mouse CYP2A5 probe.

Drug metabolism and pharmacokinetics

Volumn 21, Issue 4, 2006, Pages 277-285

  Aoki, Kimiko ^a   Kashiwagura, Yasuharu ^a   Horie, Toru ^a   Sato, Hitoshi ^a   Tateno, Chise ^a   Ozawa, Naoki ^a   Yoshizato, Katsutoshi ^a  

^a SHOWA UNIVERSITY   (Japan)

Author keywords

[No Author keywords available]

Indexed keywords

BENZALDEHYDE; BENZALDEHYDE DERIVATIVE; COUMARIN; COUMARIN 7 HYDROXYLASE; COUMARIN 7-HYDROXYLASE; COUMARIN DERIVATIVE; LACTONE; MIXED FUNCTION OXIDASE; SERUM ALBUMIN; UNSPECIFIC MONOOXYGENASE;

ANIMAL; ARTICLE; CHIMERA; DBA MOUSE; DRUG ANTAGONISM; DRUG EFFECT; HUMAN; HYDROXYLATION; LIVER; LIVER MICROSOME; MALE; METABOLISM; MOLECULAR PROBE; MOUSE;

ANIMALS; ARYL HYDROCARBON HYDROXYLASES; BENZALDEHYDES; CHIMERA; COUMARINS; HUMANS; HYDROXYLATION; LACTONES; LIVER; MALE; MICE; MICE, INBRED DBA; MICROSOMES, LIVER; MIXED FUNCTION OXYGENASES; MOLECULAR PROBES; SERUM ALBUMIN;

EID: 34547792830     PISSN: 13474367     EISSN: None     Source Type: Journal    
DOI: 10.2133/dmpk.21.277     Document Type: Article

References (0)