Vpr from HIV-1 subtypes B and C exhibit significant differences in their ability to transactivate LTR-mediated gene expression and also in their ability to promote apoptotic DNA ladder formation [4]

AIDS

Volumn 21, Issue 13, 2007, Pages 1832-1834

  Bano, Aalia S ^a   Gupta, Nidhi ^a   Sood, Vikas ^a   Banerjea, Akhil C ^a  

^a NATIONAL INSTITUTE OF IMMUNOLOGY   (India)

Author keywords

[No Author keywords available]

Indexed keywords

VPR PROTEIN;

AMINO ACID SEQUENCE; APOPTOSIS; CELL DEATH; CELL STRAIN HEK293; DNA DAMAGE; DNA ISOLATION; DNA SYNTHESIS; GENE EXPRESSION; HUMAN; HUMAN IMMUNODEFICIENCY VIRUS 1; LETTER; LEUKEMIA CELL LINE; NONHUMAN; NUCLEOTIDE SEQUENCE; POLYMERASE CHAIN REACTION; PRIORITY JOURNAL; PROMOTER REGION; PROTEIN FUNCTION; STATISTICAL SIGNIFICANCE; TRANSACTIVATION; VIRUS STRAIN;

AMINO ACID SEQUENCE; APOPTOSIS; DNA FRAGMENTATION; DNA, VIRAL; GENE PRODUCTS, VPR; HIV LONG TERMINAL REPEAT; HIV-1; HUMANS; MOLECULAR SEQUENCE DATA; TRANS-ACTIVATION (GENETICS);

EID: 34547788360     PISSN: 02699370     EISSN: None     Source Type: Journal    
DOI: 10.1097/QAD.0b013e328277f16b     Document Type: Letter

References (4)

1. Le Rouzic E, Benichou S. The Vpr protein from HIV-1: distinct roles along the viral life cycle. Retrovirology 2005; 2:11.
2. Adachi A, Glendelman HE, Koenig S, Folks T, Willey R, Rabsom A, Martin M. Production of acquired immunodeficiency syndrome associated retrovirus in human and nonhuman cells transfected with an infectious molecular clone. J Virol 1986; 59:284-291.
3. Gupta N, Sood V, Bano AS, Banerjea AC. X protein of hepatitis B virus potently activates HIV-1 subtype C-LTR promoter: implications for faster spread of HIV-1 subtype C. AIDS 2007; 21:1491-1492.
4. Li CJ, Friedman DJ, Wang C, Metelev V, Pardee AB. Induction of apoptosis in uninfected lymphycytes by HIV-1 Tat protein. Science 1995; 268:429-431.