Production of Ac-225 for cancer therapy by photon-induced transmutation of Ra-226

Applied Radiation and Isotopes

Volumn 65, Issue 9, 2007, Pages 1014-1022

  Melville, G ^a   Meriarty, H ^b   Metcalfe, P ^c   Knittel, T ^d   Allen, B J ^a,e  

^a St George Cancer Care Centre   (Australia)

^b AUSTRALIAN NUCLEAR SCIENCE AND TECHNOLOGY ORGANISATION   (Australia)

^c UNIVERSITY OF WOLLONGONG   (Australia)

^d PRINCE OF WALES HOSPITAL   (Australia)

^e ST GEORGE HOSPITAL   (Australia)

Author keywords

Ac 225; Ac Bi generator; Actinium; Alpha emitter; Bi 213; Cancer therapy; Linac; Linac production; Medical linear accelerator; Ra 225; Ra 226; Targeted alpha therapy

Indexed keywords

LINEAR ACCELERATORS; ONCOLOGY; RADIOACTIVE WASTES;

ALPHA EMITTERS; BREMSSTRAHLUNG PHOTONS; CANCER THERAPY; LINAC PRODUCTION; TARGETED ALPHA THERAPY; TRANSMUTATION;

ACTINIUM;

ACTINIUM 225; RADIUM 226;

ARTICLE; BREMS RADIATION; CANCER THERAPY; LINEAR ACCELERATOR; NUCLEAR WASTE; PHOTON; PRIORITY JOURNAL; RADIATION DOSE;

ACTINIUM; BRACHYTHERAPY; PARTICLE ACCELERATORS; PHOTONS; RADIOISOTOPES; RADIOPHARMACEUTICALS; RADIUM;

EID: 34547784492     PISSN: 09698043     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.apradiso.2007.03.018     Document Type: Article

References (15)

1. Apostolidis, C., Molinet, R., Morgenstein, A. In: Fourth Alpha-Immunotherapy Symposium. Duesseldorf, 28-29 June 2004.
2. Apostolidis C., Molinet R., Rasmussen G., and Morgenstern A. Production of Ac-225 from Th-229 for targeted alpha therapy. Anal. Chem. 77 (2005) 6288-6291
3. Berkeley Laboratory, 2006. Online: 〈http://ie.lbl.gov/education/isotopes.htm〉.
4. Bueche F. Introduction to Physics for Scientists & Engineers (1969), McGraw-Hill Co.
5. Dowsett D.J., Kenny P.A., and Johnston R.E. Physics of Diagnostic Imaging (2001), Oxford University Press
6. Koch, L., Apostolidis, C., Molinet, R., Nicolaou, W., Janssens, W., Schweikert, H. Production of Bi-213 and Ac-225. In: Α-Immuno '97 ITU Symposium. 27-28 October 1997.
7. Korea Atomic Energy Research Institute. Online: 〈http://atom.kaeri.re.kr/cgi-bin/readgam〉.
8. Los Alamos National Laboratory. Online: 〈http://t2.lanl.gov/data/decayd.html〉.
9. Maestro-32: MCA Emulator. EG & G Ortec. Online: 〈http://www.ortec-online.com/〉.
10. Melville G., Liu S.F., and Allen B.J. A theoretical model for the production of Ac-225 for cancer therapy by photon induced transmutation of Ra-226. J. Appl. Radiat. Isot. 64 9 (2006)
11. Meyerhof W. Elements of Nuclear Physics (1967), McGraw-Hill, New York
12. Morgenstern A. Radio-immunotherapy using alpha-emitting nuclides (2005), European Commission Joint Research Centre, Institute for Transuranium Elements, Karlsruhe, Germany
13. ORTEC, 2006. Online: 〈http://www.ortec-online.com/〉.
14. ORTEC User Manual: MCA Emulator for Microsoft Windows 95, 98 & NT. Manual Revision C.
15. Russell-Wehr M., and Richards J.A. Physics of the Atom (1974), Addison-Wesley