Glycyrrhizin exhibits potential chemopreventive activity on 12-O-tetradecanoyl phorbol-13-acetate-induced cutaneous oxidative stress and tumor promotion in Swiss albino mice

Journal of Enzyme Inhibition and Medicinal Chemistry

Volumn 22, Issue 3, 2007, Pages 363-369

  Rahman, Sahar ^a   Sultana, Sarwat ^a  

^a HAMDARD UNIVERSITY   (India)

Author keywords

Antioxidant enzymes; Glycyrrhizin; Oxidative stress; Protection; TPA; Tumor promotion

Indexed keywords

ACETONE; AGLYCONE; BIOLOGICAL MARKER; CATALASE; DNA; GLUTATHIONE; GLUTATHIONE PEROXIDASE; GLUTATHIONE REDUCTASE; GLUTATHIONE TRANSFERASE; GLYCYRRHETINIC ACID; GLYCYRRHIZIC ACID; LIPOXYGENASE; ORNITHINE DECARBOXYLASE; PHORBOL 13 ACETATE 12 MYRISTATE; PROSTAGLANDIN SYNTHASE;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ANTIINFLAMMATORY ACTIVITY; ARTICLE; CELL PROLIFERATION; CHEMOPROPHYLAXIS; CONTROLLED STUDY; DETOXIFICATION; DNA SYNTHESIS; DNA SYNTHESIS INHIBITION; DRUG STRUCTURE; ENZYME ACTIVITY; ENZYME INHIBITION; FEMALE; LIPID PEROXIDATION; MICROSOME; MOUSE; MOUSE STRAIN; NONHUMAN; OXIDATIVE STRESS; PRIORITY JOURNAL; SKIN INFLAMMATION; SKIN TUMOR; TUMOR PROMOTION;

ANIMALS; ANTICARCINOGENIC AGENTS; ANTIOXIDANTS; CARCINOGENS; CATALASE; DRUG EVALUATION, PRECLINICAL; DRUG SCREENING ASSAYS, ANTITUMOR; ENZYME INHIBITORS; FEMALE; GLUTATHIONE; GLUTATHIONE PEROXIDASE; GLUTATHIONE REDUCTASE; GLUTATHIONE TRANSFERASE; GLYCYRRHIZIC ACID; LIPID PEROXIDATION; MICE; ORNITHINE DECARBOXYLASE; OXIDATIVE STRESS; SKIN; SKIN NEOPLASMS; TETRADECANOYLPHORBOL ACETATE;

MUS;

EID: 34547763911     PISSN: 14756366     EISSN: 14756374     Source Type: Journal    
DOI: 10.1080/14756360601074094     Document Type: Article

References (34)

1. Qureshi, S., Shah, AH, Tariq, M. and Ageel, AM (1989) Studies on herbal aphrodisiacs used in Arab system of medicine. Amer J Chinese Med, 17, pp. 57-63.
2. Lee, SF, Liang, YC and Lin, JK (1995) Inhibition of 1,2,4-benzenetriol-generated active oxygen species and induction of phase II enzymes by green tea polyphenols. Chem Biol Interact, 98, pp. 283-301.
3. Cerutti, PA (1994) Oxy-radicals and cancer. The Lancet, 344, pp. 862-863.
4. Zhao, J., Wang, J., Chen, Y. and Agarwal, R. (1999) Antitumor promoting activity of a polyphenolic fraction isolated from grape seeds in the mouse skin two stage initiation-promotion protocol and identification of procyanidin B5-3'-gallate as the most effective antioxidant constituent. Carcinogenesis, 20, pp. 1737-1745.
5. Stromer, FC, Reisted, R. and Alexander, J. (1993) Glycyrrhizic acid in liquorice: Evaluation of health hazard. J Food Chem Toxicol, 31, pp. 303-312.
6. Akamatsu, H., Komuto, J., Asada, Y. and Niwa, Y. (1991) Mechanism of anti-inflammatory action of glycyrrhizin: Effect on neutrophil functions including reactive oxygen species generation. Planta Med, 57, pp. 119-121.
7. Wright, JR, Colby, HD and Miles, PR (1981) Cytosolic factors that affect microsomal lipid peroxidation in lung and liver. Arch Biochem Biophys, 206, pp. 296-304.
8. Jollow, DJ, Mitchell, JR, Zampaglione, N. and Gillette, JR (1974) Bromobenzene induced liver necrosis: Protective role of glutathione and evidence for 3,4-bromobenzene oxide as the hepatotoxic metabolite. Pharmacology, 11, p. 151.
9. Habig, WH, Pabst, MJ and Jakoby, WB (1974) Glutathione-S-transferases: The first enzymatic step in mercapturic acid formation. J Biol Chem, 249, pp. 7130-7139.
10. Carlberg, I. and Mannervik, B. (1975) Glutathione reductase level in rat brain. J Biol Chem, 250, pp. 5475-5480.
11. Claiborne, A. (1985) Catalase activity. CRC handbook of methods in oxygen radical research, pp. 283-284. CRC Press, Boca Raton
12. Mohandas, M., Marshal, JJ, Duggin, GG, Horvath, JS and Tiller, D. (1984) Differential distribution of glutathione and glutathione related enzymes in rabbit kidney. Cancer Res, 44, pp. 5086-5091.
13. O'Brien, TG, Simsiman, RC and Boutwell, RK (1975) Induction of the polyamine-biosynthetic enzymes in mouse epidermis and their specificity for tumor promotion. Cancer Res, 35, pp. 1662-1670.
14. Smart, HC, Huang, MT and Conney, AG (1986) Sn -1,2-Diacyglycerols mimic the effects of 12-O-tetradecanoylphorbol-13-acetate in vivo by inducing biochemical changes associated with tumor promotion in mouse epidermis. Carcinogenesis, 7, pp. 1865-1870.
15. Lowry, OH, Rosebrough, NJ, Farr, AL and Randall, RJ (1951) Protein measurement with the Folin phenol reagent. J Biol Chem, 193, pp. 265-275.
16. Sun, Y. (1990) Free radicals, antioxidants enzymes and carcinogenesis. Free Radic Biol Med, 8, pp. 583-599.
17. Halliwell, B. (1987) Oxidants and human disease: Some new concepts. FASEB J, 1, pp. 441-445.
18. Stadtman, ER (1992) Protein oxidation and ageing. Science, 257, pp. 1220-1224.
19. Huachen, W. and Krystgna, F. (1991) In vivo formation of oxidized DNA base in tumor promoter-treated mouse skin. Cancer Res, 51, p. 4443.
20. Katiyar, SK, Agarwal, R. and Mukhtar, H. (1996) Inhibition of 12-O-tetradecanoyl phorbal acetate caused tumor promotion in 7,12, dimethyl benz (a) anthracene-initiated Sincar mouse by a polyphenol fraction. Cancer Res, 56, pp. 1023-1030.
21. Xiaoguang, C., Hongyan, L., Xiaohong, L., Zhaodi, F., Yan, L., Lihua, T. and Rui, H. (1998) Cancer chemopreventive and therapeutic activities of red ginseng. J ethanopharm, 60, pp. 71-78.
22. Stoner, GD and Mukhtar, H. (1995) Polyphenols as cancer chemopreventive agents. Cell Biochem, 22, pp. 169-180.
23. Tanaka, R., Minami, T., Ishikawa, Y., Matsunaga, S., Tokuda, H. and Nishino, H. (2003) Cancer chemopreventive activity of serratane-type triterpenoids on two-stage mouse skin carcinogenesis. Cancer Lett, 196, pp. 121-126.
24. Francischetti, IMB, Monteiro, RQ and Guimaraes, JA (1997) Identification of glycyrrhizin as a thrombin inhibitor. Biochem Biophys Res Commun, 235, pp. 259-263.
25. Hurst, JK and Barrette, WC (1989) Leukocytic oxygen activation and microbicidal oxidative toxins. Crit Rev Biochem Mol Biol, 24, pp. 271-328.
26. Ramos, CL, Pou, S., Britigan, BE, Cohen, MS and Rosen, GM (1992) Spin trapping evidence for myeloperoxidase-dependent hydroxyl radical formation by human neutrophils and monocytes. J Biol Chem, 267, pp. 8307-8312.
27. Steineck, MJ, Khan, AV and Karnovsky, MJ (1992) Intracellular singlet oxygen generation by phagocytosing neutrophils in response to particles coated with a chemical trap. J Biol Chem, 267, pp. 13425-13433.
28. Ruzicka, T. and Printz, MP (1984) Arachidonic acid metabolism in skin: A review. Rev Physiol Biochem Pharmacol, 100, pp. 121-160.
29. Bonta, JL and Parnham, MJ (1978) Prostaglandins and chronic inflammation. Biochem Pharmacol, 27, pp. 1611-1623.
30. Samuelsson, B. (1983) Leukotriens: Mediators of immediate hypersensitivity reactions and inflammation. Science, 220, pp. 568-578.
31. Dhawan, D., Balasubramanian, S., Amonkar, AJ and Singh, N. (1999) Chemopreventive effect of 4′-demethyl epipodophyllotoxin on DMBA/ TPA-induced mouse skin carcinogenesis. Carcinogenesis, 20, pp. 997-1003.
32. Wilkinson IV, J. and Clapper, M. (1997) Detoxification enzymes and chemoprevention. Proc Soc Exp Biol Med, 216, pp. 192-200.
33. Maliakal, PP, Coville, PF and Wanwimolruk, S. (2001) Tea consumption modulates hepatic drug metabolizing enzymes in wistar rats. J Pharm Pharmacol, pp. 569-577.
34. Pegg, AE, Shantz, LM and Colemn, CS (1995) Ornithine decarboxylase as a target for chemoprevention. J Cell Biochem Suppl, 22, pp. 132-138.