On the way to rational freeze-drying

American Pharmaceutical Review

Volumn 9, Issue 6, 2006, Pages 37-42

  Mayeresse, Yves ^a   Veillon, Romain ^a  

^a GLAXOSMITHKLINE   (United Kingdom)

Author keywords

[No Author keywords available]

Indexed keywords

NITROGEN; WATER;

BIOTECHNOLOGY; DEFENSE MECHANISM; ENERGY TRANSFER; FACTORIAL DESIGN; FREEZE DRYING; LOW TEMPERATURE; MACROMOLECULE; REVIEW; WATER ABSORPTION;

EID: 34547749251     PISSN: 10998012     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Review

References (8)

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2. M J Pikal et al. Physical chemistry of freeze-drying: measurement of sublimation rate for frozen aqueous solution by a microbalance technique. J. Pharm. Sci. 72:635-650 (1983).
3. M Brülls, A Rasmuson. Heat transfer in vial lyophilization. Int. J. Pharm. 246:1-16(2002)
4. Chi Sung Song, J H Nam, C-J Kim, S T Ro. Temperature distribution in a vial during freeze-drying of skim milk. J. Food Engineering (2004)
5. J D Mellor. Fundamentals of freeze-drying. Academic Press 386p. (1978).
6. J Xiang, J M hey, V Liedtke, D Q Wang. Investigation of freeze-drying sublimation rates using a freeze-drying microbalance technique. Int. J. Pharm 279:95-105 (2004).
7. C Roth, G Winter, G Lee. Continuous measurement of drying rate of crystalline and amorphous system during freeze-drying using in situ microbalance technique. J. Pharm. Sci. 90-9 (2001).
8. G Schelenz, J Engel, H Rupprecht. Sublimation during lyophilization by temperature profile and X-ray technique. Int. J. Pharm 113:133-140 (1995).