A mutation in the human herpes simplex virus type 1 UL52 zinc finger motif results in defective primase activity but can recruit viral polymerase and support viral replication efficiently

Journal of Virology

Volumn 81, Issue 16, 2007, Pages 8742-8751

  Chen, Yan ^a   Livingston, Christine M ^a   Carrington Lawrence, Stacy D ^a,b   Bai, Ping ^a   Weller, Sandra K ^a  

^a UNIVERSITY OF CONNECTICUT HEALTH CENTER   (United States)

^b NATIONAL INSTITUTES OF HEALTH   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ADENOSINE TRIPHOSPHATASE; DETERGENT; DNA POLYMERASE; HELICASE; LEUCINE; PHENYLALANINE; PROTEIN UL30; PROTEIN UL5; PROTEIN UL52; PROTEIN UL8; SINGLE STRANDED DNA; UNCLASSIFIED DRUG; ZINC FINGER PROTEIN;

ANIMAL CELL; ARTICLE; CELL NUCLEUS MATRIX; CHROMATIN; COMPLEX FORMATION; CONTROLLED STUDY; ENZYME ACTIVE SITE; ENZYME ACTIVITY; ENZYME SUBUNIT; GENE MUTATION; GENETIC CONSERVATION; HERPES SIMPLEX VIRUS 1; HERPES SIMPLEX VIRUS 2; NONHUMAN; NUCLEOSOME; PRIORITY JOURNAL; PROTEIN DNA BINDING; PROTEIN PROTEIN INTERACTION; VIRUS REPLICATION; WILD TYPE; ZINC FINGER MOTIF;

AMINO ACID SEQUENCE; AMINO ACID SUBSTITUTION; ANIMALS; DETERGENTS; DNA HELICASES; DNA PRIMASE; DNA-DIRECTED DNA POLYMERASE; DNA-DIRECTED RNA POLYMERASES; EXODEOXYRIBONUCLEASES; HERPESVIRUS 1, HUMAN; HUMANS; LEUCINE; MOLECULAR SEQUENCE DATA; MUTATION; PHENYLALANINE; VIRAL PROTEINS; VIRUS REPLICATION; ZINC FINGERS;

HERPESVIRIDAE; HUMAN HERPESVIRUS 1; HUMAN HERPESVIRUS 2;

EID: 34547748348     PISSN: 0022538X     EISSN: None     Source Type: Journal    
DOI: 10.1128/JVI.00174-07     Document Type: Article

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