The synthesis of tetrahydropyridopyrimidones as a new scaffold for HIV-1 integrase inhibitors

Tetrahedron Letters

Volumn 48, Issue 37, 2007, Pages 6552-6555

  Kinzel, Olaf D ^a   Monteagudo, Edith ^a   Muraglia, Ester ^a   Orvieto, Federica ^a   Pescatore, Giovanna ^a   Ferreira, Maria del Rosario Rico ^a   Rowley, Michael ^a   Summa, Vincenzo ^a  

^a IRBM   (Italy)

Author keywords

1,2,4 Oxadiazoline; Amidoxime; Integrase inhibitor; Tetrahydropyridopyrimidone

Indexed keywords

AMINE; INTEGRASE INHIBITOR; METHYL 9 AMINO 3 HYDROXY 4 OXO 6,7,8,9 TETRAHYDRO 4H PYRIDO(1,2 ALPHA)PYRIMIDINE 2 CARBOXYLIC ACID; PYRIMIDINONE DERIVATIVE; UNCLASSIFIED DRUG;

ARTICLE; CHIRALITY; DRUG CONFORMATION; DRUG STRUCTURE; DRUG SYNTHESIS; HUMAN IMMUNODEFICIENCY VIRUS 1; STEREOCHEMISTRY;

HUMAN IMMUNODEFICIENCY VIRUS 1;

EID: 34547733410     PISSN: 00404039     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.tetlet.2007.07.043     Document Type: Article

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