Hyperforin accumulates in the translucent glands of Hypericum perforatum

Annals of Botany

Volumn 99, Issue 6, 2007, Pages 1097-1100

  Soelberg, Jens ^a   Jørgensen, Lise Bolt ^a   Jäger, Anna K ^b  

^a UNIVERSITY OF COPENHAGEN   (Denmark)

^b UNIVERSITY OF COPENHAGEN   (Denmark)

Author keywords

Hyperforin accumulation; Hypericum perforatum; Translucent gland

Indexed keywords

CHLOROPLAST; MONOTERPENE; WEED;

HYPERICUM PERFORATUM;

BICYCLO COMPOUND; DRUG DERIVATIVE; HYPERFORIN; PHLOROGLUCINOL; TERPENE;

ARTICLE; CHEMICAL STRUCTURE; CHEMISTRY; CYTOLOGY; HIGH PERFORMANCE LIQUID CHROMATOGRAPHY; HYPERICUM; MEDICINAL PLANT; METABOLISM; PLANT LEAF; ULTRAVIOLET SPECTROPHOTOMETRY;

BICYCLO COMPOUNDS; CHROMATOGRAPHY, HIGH PRESSURE LIQUID; HYPERICUM; MOLECULAR STRUCTURE; PHLOROGLUCINOL; PLANT LEAVES; PLANTS, MEDICINAL; SPECTROPHOTOMETRY, ULTRAVIOLET; TERPENES;

EID: 34547729260     PISSN: 03057364     EISSN: 10958290     Source Type: Journal    
DOI: 10.1093/aob/mcm057     Document Type: Article

References (19)

1. Adam P, Arigoni D, Bacher A, Eisenreich W. 2002. Biosynthesis of hyperforin in Hypericum perforatum. Journal of Medicinal Chemistry 45: 4786-4793.
2. Beerhues L. 2006. Hyperforin. Phytochemistry 67: 2201-2207.
3. Brolis M, Gabetta B, Fuzzati N, Pace R, Panzeri F, Peterlongo F. 1998. Identification by high-performance liquid chromatography-diode array detection-mass spectrometry and quantification by high-performance liquid chromatography-UV absorbance detection of active constituents of Hypericum perforatum. Journal of Chromatography A 825: 9-16.
4. Chatterjee SS, Nöldner M, Koch E, Erdelmeier C. 1998. Antidepressant activity of Hypericum perforatum and hyperforin: the neglected possibility. Pharmacopsychiatry 31: 7-15.
5. Ciccarelli D, Andreucci AC, Pagni AM. 2001a. The "black nodules" of Hypericum perforatum L. subsp. perforatum: morphological, anatomical, and histochemical studies during the course of ontogenesis. Israel Journal of Plant Sciences 49: 33-40.
6. Ciccarelli D, Andreucci AC, Pagni AM. 2001b. Translucent glands and secretory canals in Hypericum perforatum L. (Hyperiacaceae): morphological, anatomical and histochemical studies during the course of ontogenesis. Annals of Botany 88: 637-644.
7. Croteau R. 1987. Biosynthesis and catabolism of monoterpenoids. Chemical Review 87: 929-954.
8. Curtis JD, Lersten NR. 1990. Internal secretory structures in Hypericum (Clusiaceae): H. perforatum L. and H. balearicum L. New Phytologist 114: 571-580.
9. Feder N, O'Brien TP. 1968. Plant microtechnique - some principles and new methods. American Journal of Botany 55: 123-139.
10. Kubin A, Wierrani F, Burner U, Alth G, Grünburger W. 2005. Hypericin - the facts about a controversial agent. Current Pharmaceutical Design 11: 233-253.
11. Maffi L, Camoni L, Fornasiero RB, Bianci A. 2005. Morphology and development of secretory structures in Hypericum perforatum and H. richeri. Nordic Journal of Botany 23: 453-461.
12. Mathis C, Ourisson G. 1963. Étude chemio-taxonomique du genre Hypericum I. Répartition de l'hypéricine. Phytochemistry 2: 157-171.
13. Philipp M, Kohnen R, Hiller K-O. 1999. Hypericum extract versus imipramine or placebo in patients with moderate depression: randomised multicentre study of treatment for eight weeks. British Medical Journal 319: 1534-1539.
14. Piovan A, Filippini R, Caniato R, Borsarini A, Maleci LB, Cappelletti EM. 2004. Detection of hypericins in the "red glands" of Hypericum elodes by ESI-MS/MS. Phytochemistry 65: 411-414.
15. de los Reyes GC, Koda RT. 2001. Development of a simple, rapid and reproducible HPLC assay for the simultaneous determination of hypericins and hyperforin in commercial St. John's Wort preparations. Journal of Pharmaceutical and Biomedical Analysis 26: 959-965.
16. Robson NKB. 1981. Studies in the genus Hypericum L. (Guttiferae) 2. Characters of the genus. Bulletin of the British Museum (Natural History) Botany Series 8: 55-226.
17. Schmitt LA, Liu Y, Murphy PA, Petrich JW, Dixon PM, Birt DF. 2006. Reduction in hypericin-induced phototoxicity by Hypericum perforatum extracts and pure compounds. Journal of Photochemistry and Photobiology B: Biology 85: 118-130.
18. Zobayed SMA, Afreen F, Kozai T. 2005. Temperature stress can alter the photosynthetic efficiency and secondary metabolite concentration in St. John's wort. Plant Physiology and Biochemistry 43: 977-984.
19. Zobayed SMA, Afreen F, Goto E, Kozai T. 2006. Plant-environment interactions: accumulation of hypericin in dark glands of Hypericum perforatum. Annals of Botany 98: 793-804.