In vivo biostability of polysiloxane polyether polyurethanes: Resistance to biologic oxidation and stress cracking

Journal of Biomedical Materials Research - Part A

Volumn 77, Issue 3, 2006, Pages 580-589

  Ward, Robert ^a   Anderson, James ^b   McVenes, Rick ^c   Stokes, Ken ^c  

^a Polymer Technology Group   (United States)

^b CASE WESTERN RESERVE UNIVERSITY   (United States)

^c MEDTRONIC INC   (United States)

Author keywords

Autoxidation; Biostability; Environmental stress cracking; Polysiloxane polyether polyurethane

Indexed keywords

CHEMICAL STABILITY; OXIDATION; POLYETHERS; SILICONES; STRESS CORROSION CRACKING;

AUTOXIDATION; BIOSTABILITY; ENVIRONMENTAL STRESS CRACKING; IMPLANTABLE DEVICES; POLYSILOXANE POLYETHER POLYURETHANE;

POLYURETHANES;

POLYETHER; POLYSILOXANE; POLYURETHAN;

ANIMAL EXPERIMENT; ARTICLE; AUTOOXIDATION; BIOCOMPATIBILITY; BIODEGRADATION; CONTROLLED STUDY; IMPLANT; MECHANICAL STRESS; NONHUMAN; RABBIT; SURFACE PROPERTY;

ANIMALS; BIOCOMPATIBLE MATERIALS; MATERIALS TESTING; OXIDATION-REDUCTION; POLYURETHANES; PROSTHESES AND IMPLANTS; RABBITS; SILOXANES;

EID: 34547723163     PISSN: 15493296     EISSN: 15524965     Source Type: Journal    
DOI: 10.1002/jbm.a.30555     Document Type: Article

References (17)

1. Stokes K. Biodegradation. Cardiovasc Pathol 1993;2(3 Suppl): 111S-119S.
2. Zhao Q, Agger MP, Fitzpatrick M, Anderson JM, Stokes K, Urbanski P. In vivo studies of stress-cracking in polyetherurethanes using the cage implant system. In: Transactions of the 15th Annual Meeting of the Society for Biomaterials, Lake Buena Vista, FL; 1989. p 203.
3. Zhao Q, Agger MP, Fitzpatrick M, Anderson JM, Stokes K, Urbanski P. Cellular interactions with biomaterials: In vivo cracking of stressed polyetherurethanes. J Biomed Mater Res 1990;24:621-637.
4. Anderson JM, Hiltner A, Zhao QH, Wu Y, Renier M, Schubert M, Brunstedt M, Lodoen GA, Payet CR. Cell/polymer interactions in the biodegradation of polyurethanes. In: Vert M, Feijen J, Albertsson A, Scott G, Chiellini E, editors. Biodegradable Polymers and Plastics. Cambridge, England: Royal Society of Chemistry; 1992. pp 122-136.
5. Stokes K, Anderson J, McVenes R, McClay C. The encapsulation of transvenous polyurethane insulated cardiac pacemaker leads. Cardiovasc Pathol 1995;4:163-172.
6. Wilkoff BL. Results with different extraction methods (success rate and complications). Europace Suppl 2000;1:D46.
7. Ebert M, Ward R, Anderson JM, McVenes R, Stokes K. In vivo biostability of polyether polyurethanes with polyethylene oxide surface modifying endgroups: resistance to biologic oxidation and stress cracking. J Biomed Mater Res. 2005;75A:175-184.
8. Ward R, Anderson JM, Ebert M, McVenes R, Stokes K. In vivo biostability of polysiloxane polyether polyurethanes: resistance to metal ion oxidation. J Biomed Mater Res. In press.
9. Wu Y, Sellitti C, Anderson JM, Hiltner A, Lodoen GA, Payet CR. An FTIR-ATR investigation of in vivo poly(ether urethane) degradation. J Appl Polym Sci 1992;46:201-211.
10. Beyersdorf F, Kreuzer J, Zegrlman M. Polyurethane insulated cardiac pacing leads. An overview after eight years. Clin Prog Electrophysiol Pacing 1986;4:199-204.
11. Stokes KB, Frazer AW, Carter EA. The biostability of various polyether polyurethanes under stress. ANTEC '84, 1984;1073-1075.
12. 2- macroglobulin promotes in vitro oxidative stress cracking of Pellethane 2363-80A. In vivo and in vitro correlations. J Biomed Mater Res 1993;27:379-389.
13. Medtronic Product Performance Report, 1st ed. 2004. See also www.MedtronicConnect.com.
14. Stokes, KB. Polyether polyurethanes: Biostable or not? J Biomater Appl 1988;3:228-260.
15. Wu YK, Sletten KR, Topolkaraev V, Lodoen GA, Anderson JM, Baer E, Hiltner A. Effect of an oxidative environment on the creep compliance of poly(ether urethane urea). J Appl Polym Sci 1994;53:1037-1049.
16. Schubert MA, Wiggins MJ, Defife KM, Hiltner A, Anderson JM. Vitamin E as an antioxidant for poly(etherurethane urea): In vivo studies. J Biomed Mater Res 1996;32:493-504.
17. Bonart R. X-ray investigations concerning the physical structure of crosslinking in segmented urethane elastomers. J Macromol Sci Phys B 1968;7:115-138.