Biological conversion of a water-soluble prodrug of cyclosporine A

European Journal of Pharmaceutics and Biopharmaceutics

Volumn 67, Issue 2, 2007, Pages 555-561

  Lallemand, F ^a   Varesio, E ^a   Felt Baeyens, O ^a   Bossy, Leila ^a   Hopfgartner, G ^a   Gurny, R ^a  

^a UNIVERSITY OF GENEVA   (Switzerland)

Author keywords

Biotransformation; Cyclosporine A; Enzymes; LC MS; MS MS; Prodrug; Tears

Indexed keywords

CYCLOSPORIN A; PHOSPHATASE; PRODRUG; UNCLASSIFIED DRUG; UNIL 088;

ARTICLE; BIOTRANSFORMATION; DRUG HYDROLYSIS; DRUG METABOLISM; DRUG STRUCTURE; LACRIMAL FLUID; QUADRUPOLE MASS SPECTROMETRY; RABBIT; TEMPERATURE; TIME OF FLIGHT MASS SPECTROMETRY;

ANIMALS; BIOTRANSFORMATION; CHROMATOGRAPHY, ION EXCHANGE; CHROMATOGRAPHY, LIQUID; CYCLOSPORINE; CYCLOSPORINS; HYDROLYSIS; MASS SPECTROMETRY; MODELS, CHEMICAL; PHOSPHATES; PRODRUGS; RABBITS; SOLUBILITY; TEARS; TEMPERATURE; WATER;

EID: 34547697313     PISSN: 09396411     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.ejpb.2007.03.011     Document Type: Article

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