Prevention of red cell alloimmunization by CD25 regulatory T cells in mouse models

American Journal of Hematology

Volumn 82, Issue 8, 2007, Pages 691-696

  Yu, Jin ^a   Heck, Susanne ^a   Yazdanbakhsh, Karina ^a  

^a NEW YORK BLOOD CENTER   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ALLOANTIBODY; BLOOD GROUP ANTIGEN; CD4 ANTIGEN; GLYCOPHORIN A; IMMUNOGLOBULIN G ANTIBODY; IMMUNOGLOBULIN M ANTIBODY; INTERLEUKIN 2 RECEPTOR ALPHA;

ADOPTIVE TRANSFER; ALLOIMMUNIZATION; ANIMAL CELL; ANIMAL EXPERIMENT; ANTIBODY PRODUCTION; ANTIBODY RESPONSE; ARTICLE; AUTOIMMUNE DISEASE; B LYMPHOCYTE ACTIVATION; BLOOD TRANSFUSION; CD25+ T LYMPHOCYTE; CD4+ CD25+ T LYMPHOCYTE; CONTROLLED STUDY; ERYTHROCYTE; FEMALE; IMMUNIZATION; IMMUNOLOGICAL TOLERANCE; IMMUNOREGULATION; IMMUNOTHERAPY; INCIDENCE; MACROPHAGE; MOUSE; NONHUMAN; ORGAN TRANSPLANTATION; PRIORITY JOURNAL; RECIPIENT; REGULATORY T LYMPHOCYTE; SICKLE CELL ANEMIA; T LYMPHOCYTE SUBPOPULATION; TRANSGENIC MOUSE; WILD TYPE;

ADOPTIVE TRANSFER; ANIMALS; ANTIGENS; B-LYMPHOCYTES; ERYTHROCYTES; FEMALE; HUMANS; IMMUNITY, NATURAL; IMMUNIZATION; INTERLEUKIN-2 RECEPTOR ALPHA SUBUNIT; ISOANTIBODIES; MACROPHAGES; MICE; MICE, INBRED C57BL; MODELS, ANIMAL; RATS; SPLEEN; T-LYMPHOCYTES, REGULATORY;

EID: 34547697280     PISSN: 03618609     EISSN: 10968652     Source Type: Journal    
DOI: 10.1002/ajh.20959     Document Type: Article

References (40)

1. Adams RJ, McKie VC, Hsu L, et al. Prevention of a first stroke by transfusions in children with sickle cell anemia and abnormal results on transcranial Doppler ultrasonography. N Engl J Med 1998;339:5-11.
2. Adams RJ, Brambilla D. Discontinuing prophylactic transfusions used to prevent stroke in sickle cell disease. N Engl J Med 2005;353:2769-2778.
3. Aygun B, Padmanabhan S, Paley C, Chandrasekaran V. Clinical significance of RBC alloantibodies and autoantibodies in sickle cell patients who received transfusions. Transfusion 2002;42:37-43.
4. Singer ST, Wu V, Mignacca R, et al. Alloimmunization and erythrocyte autoimmunization in transfusion-dependent thalassemia patients of predominantly Asian descent. Blood 2000;96:3369-3373.
5. Zumberg MS, Procter JL, Lottenberg R, et al. Autoantibody formation in the alloimmunized red blood cell recipient: Clinical and laboratory implications. Arch Intern Med 2001;161:285-290.
6. Ameen R, Al Shemmari S, Al Humood S, et al. RBC alloimmunization and autoimmunization among transfusion-dependent Arab thalassemia patients. Transfusion 2003;43:1604-1610.
7. Young PP, Uzieblo A, Trulock E, et al. Autoantibody formation after alloimmunization: Are blood transfusions a risk factor for autoimmune hemolytic anemia? Transfusion 2004;44:67-72.
8. Hendrickson JE, Desmarets M, Deshpande SS, et al. Recipient inflammation affects the frequency and magnitude of immunization to transfused red blood cells. Transfusion 2006;46:1526-1536.
9. + regulatory T cells for immunologic self-tolerance and negative control of immune responses. Ann Rev Immunol 2004;22:531-562.
10. Thompson C, Powrie F. Regulatory T cells. Curr Opin Pharmacol 2004;4:408-414.
11. + regulatory T cells that prevent allograft rejection does not compromise immunity to a viral pathogen. J Immunol 2005;174:3290-3297.
12. Auffray I, Marfatia S, De Jong K, et al. Glycophorin A dimerization and band 3 interaction during erythroid membrane biogenesis: In vivo studies in human glycophorin A transgenic mice. Blood 2001;97:2872-2878.
13. Halverson G, Chaudhuri A, Huang T, et al. Immunization of transgenic mice for production of MoAbs directed at polymorphic blood group antigens. Transfusion 2001;41:1393-1396.
14. Campbell-Lee SA, Liu J, Velliquette RW, et al. The production of red blood cell alloantibodies in mice transfused with blood from transgenic Fyb-expressing mice. Transfusion 2006;46:1682-1688.
15. Lagrange PH, Mackaness GB, Miller TE. Influence of dose and route of antigen injection on the immunological induction of T cells. J Exp Med 1974;139:528-542.
16. Babcock GF, Alexander JW. The effects of blood transfusion on cytokine production by TH1 and TH2 lymphocytes in the mouse. Transplantation 1996;61:465-468.
17. Playfair JH, Marshall-Clarke S. Induction of red cell autoantibodies in normal mice. Nat New Biol 1973;243:213-214.
18. Barker RN, Casswell KM, Elson CJ. Identification of murine erythrocyte autoantigens and cross-reactive rat antigens. Immunology 1993;78:568-573.
19. Barker RN, Hall AM, Standen GR, et al. Identification of T-cell epitopes on the rhesus polypeptides in autoimmune hemolytic anemia. Blood 1997;90:2701-2715.
20. Barker RN, Shen CR, Elson CJ. T-cell specificity in murine autoimmune haemolytic anaemia induced by rat red blood cells. Clin Exp Immunol 2002;129:208-213.
21. Cooke A, Hutchings PR, Playfair JH. Suppressor T cells in experimental autoimmune haemolytic anaemia. Nature 1978;273:154-155.
22. Naysmith JD, Ortega-Pierres MG, Elson CJ. Rat erythrocyte-induced antierythrocyte autoantibody production and control in normal mice. Immunol Rev 1981;55:55-87.
23. Krieg AM. CpG motifs in bacterial DNA and their immune effects. Ann Rev Immunol 2002;20:709-760.
24. + regulatory T cells control induction of autoimmune hemolytic anemia. Blood 2005;105:3746-3748.
25. Krieg AM. Therapeutic potential of Toll-like receptor 9 activation. Nat Rev Drug Discov 2006;5:471-484.
26. Krieg AM, Yi AK, Matson S, et al. CpG motifs in bacterial DNA trigger direct B-cell activation. Nature 1995;374:546-549.
27. Tighe H, Takabayashi K, Schwartz D, et al. Conjugation of protein to immunostimulatory DNA results in a rapid, long-lasting and potent induction of cell-mediated and humoral immunity. Eur J Immunol 2000;30:1939-1947.
28. Sparwasser T, Koch ES, Vabulas RM, et al. Bacterial DNA and immunostimulatory CpG oligonucleotides trigger maturation and activation of murine dendritic cells. Eur J Immunol 1998;28:2045-2054.
29. + T cell-mediated suppression by dendritic cells. Science 2003;299:1033-1036.
30. Bluestone JA, Abbas AK. Natural versus adaptive regulatory T cells. Nat Rev Immunol 2003;3:253-257.
31. Cottrez F, Groux H. Specialization in tolerance: Innate CD(4+)CD(25+) versus acquired TR1 and TH3 regulatory T cells. Transplantation 2004;77:S12-S15.
32. Barrat FJ, Cua DJ, Boonstra A, et al. In vitro generation of interleukin 10-producing regulatory CD4(+) T cells is induced by immunosuppressive drugs and inhibited by T helper type 1 (Th1)- and Th2-inducing cytokines. J Exp Med 2002;195:603-616.
33. Chen Y, Inobe J, Marks R, et al. Peripheral deletion of antigen-reactive T cells in oral tolerance. Nature 1995;376:177-180.
34. Tang Q, Adams JY, Tooley AJ, Bi M, et al. Visualizing regulatory T cell control of autoimmune responses in nonobese diabetic mice. Nat Immunol 2006;7:83-92.
35. Groux H, Fournier N, Cottrez F. Role of dendritic cells in the generation of regulatory T cells. Semin Immunol 2004;16:99-106.
36. + regulatory T cells. J Immunol 2005;175:4180-4183.
37. + T cells selectively kill B lymphocytes. Blood 2006;107:3925-3932.
38. Wood KJ, Sakaguchi S. Regulatory T cells in transplantation tolerance. Nat Rev Immunol 2003;3:199-210.
39. Wing K, Fehervari Z, Sakaguchi S. Emerging possibilities in the development and function of regulatory T cells. Int Immunol 2006;18:991-1000.
40. + Tregs and immune control. J Clin Invest 2004;114:1209-1217.