The tyrosine degradation gene hppD is transcriptionally activated by HpdA and repressed by HpdR in Streptomyces coelicolor, while hpdA is negatively autoregulated and repressed by HpdR

Molecular Microbiology

Volumn 65, Issue 4, 2007, Pages 1064-1077

  Yang, Haihua ^a   Wang, Linqi ^a,b   Xie, Zhoujie ^a,b   Tian, Yuqing ^a   Liu, Gang ^a   Tan, Huarong ^a  

^a INSTITUTE OF MICROBIOLOGY   (China)

^b UNIVERSITY OF CHINESE ACADEMY OF SCIENCES   (China)

Author keywords

[No Author keywords available]

Indexed keywords

4 HYDROXYPHENYLACETATE DIOXYGENASE; CARBON; DIOXYGENASE; PIGMENT; PROTEIN; TYROSINE; UNCLASSIFIED DRUG;

ARTICLE; AUTOREGULATION; CATABOLISM; DNA FOOTPRINTING; ENERGY; ENZYME DEGRADATION; ENZYME SUBSTRATE; GEL MOBILITY SHIFT ASSAY; GENE ACTIVATION; GENE CONTROL; GENE REPRESSION; GENETIC TRANSCRIPTION; LIGAND BINDING; NONHUMAN; PRIORITY JOURNAL; PROMOTER REGION; STREPTOMYCES COELICOLOR; TRANSCRIPTION INITIATION;

BACTERIAL PROTEINS; BASE SEQUENCE; BIOMASS; CHROMOSOMES, BACTERIAL; DNA FOOTPRINTING; DNA PROBES; DOWN-REGULATION; FOOD; GENE EXPRESSION REGULATION, BACTERIAL; GENES, BACTERIAL; MOLECULAR SEQUENCE DATA; PHENOTYPE; PHENYLPYRUVIC ACIDS; PROMOTER REGIONS (GENETICS); PROTEIN BINDING; REPRESSOR PROTEINS; STREPTOMYCES COELICOLOR; TRANS-ACTIVATION (GENETICS); TYROSINE;

STREPTOMYCES COELICOLOR;

EID: 34547693396     PISSN: 0950382X     EISSN: 13652958     Source Type: Journal    
DOI: 10.1111/j.1365-2958.2007.05848.x     Document Type: Article

References (44)

1. Altschul, S.F., Madden, T.L., Schaffer, A.A., Zhang, J., Zhang, Z., Miller, W. Lipman, D.J. (1997) Gapped BLAST and PSI-BLAST: a new generation of protein database search programs. Nucleic Acids Res 125 : 3389 3402.
2. Arias-Barrau, E., Olivera, E.R., Luengo, J.M., Fernandez, C., Galan, B., Garcia, J.L., et al. (2004) The homogentisate pathway: a central catabolic pathway involved in the degradation of L-phenylalanine, L-tyrosine, and 3-hydroxyphenylacetate in Pseudomonas putida. J Bacteriol 186 : 5062 5077.
3. Barnes, M.R., Duetz, W.A. Williams, P.A. (1997) A 3-(3-hydroxyphenyl) propionic acid catabolic pathway in Rhodococcus globerulus PWD1: cloning and characterization of the hpp operon. J Bacteriol 179 : 6145 6153.
4. Bierman, M., Logan, R., O'Brien, K., Seno, E.T., Rao, R.N. Schoner, B.E. (1992) Plasmid cloning vectors for the conjugal transfer of DNA from Escherichia coli to Streptomyces spp. Gene 116 : 43 49.
5. Brinkman, A.B., Ettema, T.J., de Vos, W.M. van der Oost, J. (2003) The Lrp family of transcriptional regulators. Mol Microbiol 48 : 287 294.
6. Brownlee, J.M., Johnson-Winters, K., Harrison, D.H. Moran, G.R. (2004) Structure of the ferrous form of (4-hydroxyphenyl) pyruvate dioxygenase from Streptomyces avermitilis in complex with the therapeutic herbicide, NTBC. Biochemistry 43 : 6370 6377.
7. Chater, K.F. (2000) Developmental decisions during sporulation in the mycelium in Streptomyces. In Procaryote Development. Brun, Y.V. Shimkets, L. J. (eds). Washington, DC : American Society for Microbiology, pp. 33 48.
8. Cui, Y., Midkiff, M.A., Wang, Q. Calvo, J.M. (1996) The leucine-responsive regulatory protein (Lrp) from Escherichia coli. J Biol Chem 271 : 6611 6617.
9. Denoya, C.D., Skinner, D.D. Morgenstern, M.R. (1994) A Streptomyces avermitilis gene encoding a 4-hydroxyphenylpyruvic acid dioxygenase-like protein that directs the production of homogentisic acid and an ochronotic pigment in Escherichia coli. J Bacteriol 176 : 5312 5319.
10. Elliot, M.A., Bibb, M.J., Buttner, M.J. Leskiw, B.K. (2001) BldD is a direct regulator of key developmental genes in Streptomyces coelicolor A3 (2). Mol Microbiol 40 : 257 269.
11. Eustaquio, A.S., Luft, T., Wang, Z.X., Gust, B., Chater, K.F., Li, S.M. Heide, L. (2003) Novobiocin biosynthesis: inactivation of the putative regulatory gene novE and heterologous expression of genes involved in aminocoumarin ring formation. Arch Microbiol 180 : 25 32.
12. Grompe, M. (2001) The pathophysiology and treatment of hereditary tyrosinemia type I. Semin Liver Dis 21 : 563 571.
13. Hojati, Z., Milne, C., Harvey, B., Gordon, L., Borg, M., Flett, F., et al. (2002) Structure, biosynthetic origin, and engineered biosynthesis of calcium-dependent antibiotics from Streptomyces coelicolor. Chem Biol 9 : 1175 1187.
14. Janssen, G.R. Bibb, M.J. (1993) Derivatives of pUC18 that have BglII sites flanking a modified multiple cloning sites and that retain the ability to identify recombinant clones by visual screening of Esherichia coli colonies. Gene 124 : 133 134.
15. Johnson-Winters, K., Purpero. V.M., Kavana, M., Nelson, T. Moran, G.R. (2003) (4-hydroxyphenyl) pyruvate dioxygenase from Streptomyces avermitilis: the basis for ordered substrate addition. Biochemistry 42 : 2072 2080.
16. Kieser, T., Bibb, M.J., Buttner, M.J., Chater, K.F. Hopwood, D.A. (2000) Practical Streptomyces Genetics. Norwich : The John Innes Foundation.
17. Keuntje, B., Masepohl, B. Klipp, W. (1995) Expression of the putA gene encoding proline dehydrogenase from Rhodobacter capsulatus is independent of NtrC regulation but requires an Lrp-like activator protein. J Bacteriol 177 : 6432 6439.
18. Kuhstoss, S. Rao, R.N. (1991) Analysis of the integration function of the streptomycete bacteriophage phi C31. J Mol Biol 222 : 897 908.
19. Lipman, D.J. Pearson, W.R. (1985) Rapid and sensitive protein similarity searches. Science 227 : 1435 1441.
20. Liu, G., Tian, Y., Yang, H. Tan, H. (2005) A pathway-specific transcriptional regulatory gene for nikkomycin biosynthesis in Streptomyces anscochromogenes that also influences colony development. Mol Microbiol 55 : 1855 1866.
21. Lodwig, E., Kumar, S., Allaway, D., Bourdes, A., Prell, J., Priefer, U. Poole, P. (2004) Regulation of L-alanine dehydrogenase in Rhizobium leguminosarum bv. Viciae and its role in pea nodules. J Bacteriol 186 : 842 849.
22. MacNeil, D.J., Gewain, K.M., Ruby, C.L., Dezeny, G., Giggons, P.H. MacNeil, T. (1992) Analysis of Streptomyces avermitilis genes required for avermectin biosynthesis utilizing a novel integration vector. Gene 111 : 61 68.
23. Mikami, Y., Takahashi, K., Yazawa, K., Arai, T., Namikoshi, M., Iwasak, S. Okuda, S. (1985) Biosynthetic studies on Saframycin A, a quinone antitumor antibiotic produced by Streptomyces lavendulae. J Biol Chem 260 : 344 348.
24. Milcamps, A. de Bruijn, F.J. (1999) Identification of a novel nutrient-deprivation-induced Sinorhizobium meliloti gene (hmgA) involved in the deprivation of tyrosine. Microbiol 145 : 935 947.
25. Milcamps, A., Struffi, P. de Bruijn, F.J. (2001) The Sinorhizobium meliloti nutrient-deprivation-induced tyrosine degradation gene hmgA is controlled by a noval member of the arsR family of regulatory genes. Appl Environ Microbiol 67 : 2641 2648.
26. Molina-Henares, A.J., Krell, T., Eugenia Guazzaroni, M., Segura, A. Ramos, J.L. (2006) Members of the IclR family of bacterial transcriptional regulators function as activators and/or repressors. FEMS Microbiol Rev 30 : 157 186.
27. Morales, G., Linares, J.F., Beloso, A., Albar, J.P., Martinez, J.L. Rojo, F. (2004) The Pseudomonas putida Crc global regulator controls the expression of genes from several chromosomal catabolic pathways for aromatic compounds. J Bacteriol 186 : 1337 1344.
28. Moran, G.R. (2005) 4-hydroxyphenylpyruvate dioxygenase. Arch Biochem Biophy 433 : 117 128.
29. Neidig, M.L., Decker, A., Kavana, M., Moran, G.R. Solomon, E.I. (2005) Spectroscopic and computational studies of NTBC bound to the non-heme iron enzyme (4-hydroxyphenyl) pyruvate dioxygenase: active site contributions to drug inhibition. Biochem Biophys Res Commun 338 : 206 214.
30. Neusser, D., Schmidt, H., Spizek, J., Novotna, J., Peschke, U., Kaschabeck, S., et al. (1998) The genes lmbB1 and lmbB2 of Streptomyces lincolnensis encode enzymes involved in the conversion of L-tyrosine to propylproline during the biosynthesis of the antibiotic lincomycin A. Arch Microbiol 169 : 322 332.
31. Pittard, J., Camakaris, H. Yang, J. (2005) The TyrR regulon. Mol Microbiol 55 : 16 26.
32. Poggio, S., Domeinzain, C., Osorio, A. Camarena, L. (2002) The nitrogen assimilation control (Nac) protein represses asnC and asnA transcription in Escherichia coli. FEMS Microbiol Lett 206 : 151 156.
33. Pojer, F., Wemakor, E., Kammerer, B., Chen, H., Walsh, C.T., Li, S.M. Heide, L. (2003) CloQ, a prenyltransferase involved in clorobiocin biosynthesis. Proc Natl Acad Sci USA 100 : 2316 2321.
34. Pometto, A.L., 3rd. Crawford, D.L. (1985) L-phenylalanine and L-tyrosine catabolism by selected Streptomyce species. Appl Environ Microbiol 49 : 727 729.
35. Popp, R., Kohl, T., Patz, P., Trautwein, G. Gerischer, U. (2002) Differential DNA binding of transcriptional regulator PcaU from Acinetobacter sp. Strain ADP1. J Bacteriol 184 : 1988 1997.
36. Sambrook, J., Fritsch, E.F. Maniatis, T. (1989) Molecular Cloning: A Laboratory Manual. Cold Spring Harbor, NY : Cold Spring Harbor Laboratory.
37. Tan, H., Yang, H., Tian, Y., Wu, W., Whatling, C.A., Chamberlin, L.C., et al. (1998) The Streptomyces coelicolor sporulation-specific σwhiG form of RNA polymerase transcribes a gene encoding a ProX-like protein that is dispensable for sporulation. Gene 212 : 137 146.
38. Tang, L. Hutchinson, C.R. (1995) Regulation of expression of the valine (branched-chain amino acid) dehydrogenase-encoding gene from Streptomyces coelicolor. Gene 162 : 69 74.
39. Thaw, P., Sedelnikova, S.E., Muranova, T., Wiese, S., Ayora, S., Alonso, J.C., et al. (2006) Structural insight into gene transcriptional regulation and effector binding by the Lrp/AsnC family. Nucleic Acids Res 34 : 1439 1449.
40. Torres, B., Porras, G., Garcia, J.L. Diaz, E. (2003) Regulation of the mhp cluster responsible for 3-(3-hydroxyphenyl) propionic acid degradation in Escherichia coli. J Biol Chem 278 : 27575 27585.
41. Yamamoto, K. Ishihama, A. (2003) Two different modes of transcription repression of the Escherichia coli acetate operon by IclR. Mol Microbiol 47 : 183 194.
42. Yamazaki, H., Ohnishi, Y. Horinouchi, S. (2000) An A-factor-dependent extracytoplasmic function sigma factor (σAdsA) that is essential for morphological development in Streptomyces griseus. J Bacteriol 182 : 4596 4605.
43. Yang, J., Camakaris, H. Pittard, J. (2002) Molecular analysis of tyrosine- and phenylalanine-mediated repression of the tyrB promoter by the TyrR protein of Escherichia coli. Mol Microbiol 45 : 1407 1419.
44. Yokoyama, K., Ishijima, S.A., Clowney, L., Koike, H., Aramaki, H., Tanaka, C., et al. (2006) Feast/famine regulatory proteins (FFRPs): Escherichia coli Lrp, AsnC and related archaeal transcription factors. FEMS Microbiol Rev 30 : 89 108.