Modeling the norketamine metabolite in children and the implications for analgesia

Paediatric Anaesthesia

Volumn 17, Issue 9, 2007, Pages 831-840

  Herd, David W ^a   Anderson, Brian J ^b   Holford, Nicholas H G ^b  

^a STARSHIP CHILDREN S HOSPITAL   (New Zealand)

^b UNIVERSITY OF AUCKLAND   (New Zealand)

Author keywords

Allometrics; Analgesia; Children; Ketamine; Norketamine; Pharmacokinetics

Indexed keywords

DRUG METABOLITE; KETAMINE; NORKETAMINE; PLACEBO; UNCLASSIFIED DRUG;

ADULT; AGED; ALLOMETRY; ANALGESIA; ARTICLE; CHILD; COMPARTMENT MODEL; CONTINUOUS INFUSION; CONTROLLED STUDY; DISTRIBUTION VOLUME; DRUG CLEARANCE; DRUG HALF LIFE; DRUG METABOLISM; EMERGENCY WARD; FEMALE; HUMAN; MALE; NONLINEAR SYSTEM; PRIORITY JOURNAL; RACEMIC MIXTURE; SEDATION; SIMULATION; SINGLE DRUG DOSE;

ADULT; AGED; ANALGESIA; ANALYSIS OF VARIANCE; ANESTHETICS, DISSOCIATIVE; CHILD; CHILD, PRESCHOOL; CHROMATOGRAPHY, HIGH PRESSURE LIQUID; CONSCIOUS SEDATION; FEMALE; HUMANS; INFUSIONS, INTRAVENOUS; INJECTIONS, INTRAMUSCULAR; KETAMINE; MALE; MASS SPECTROMETRY; MIDDLE AGED; MODELS, STATISTICAL; POPULATION; REFERENCE STANDARDS; REPRODUCIBILITY OF RESULTS; SOLID PHASE EXTRACTION;

EID: 34547670977     PISSN: 11555645     EISSN: 14609592     Source Type: Journal    
DOI: 10.1111/j.1460-9592.2007.02257.x     Document Type: Article

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