Blocking leukotrienes optimize asthma control: The BLOC survey

Annals of Thoracic Medicine

Volumn 2, Issue 3, 2007, Pages 99-102

  Idrees, Majdy ^a   Al Moamary, Mohamed ^b  

^a Prince Sultan Military Medical City   (Saudi Arabia)

^b KING SAUD BIN ABDULAZIZ UNIVERSITY FOR HEALTH SCIENCES   (Saudi Arabia)

Author keywords

Asthma; Inflammation

Indexed keywords

BECLOMETASONE; BETA ADRENERGIC RECEPTOR STIMULATING AGENT; BUDESONIDE; CORTICOSTEROID; FLUTICASONE; LEUKOTRIENE; LEUKOTRIENE RECEPTOR BLOCKING AGENT; MONTELUKAST;

ADD ON THERAPY; ADULT; ARTICLE; ASTHMA; CLINICAL TRIAL; CONTROLLED CLINICAL TRIAL; CONTROLLED STUDY; CROSS-SECTIONAL STUDY; DISEASE SEVERITY; DOSE RESPONSE; DRUG EFFICACY; FEMALE; FOLLOW UP; HUMAN; MAJOR CLINICAL STUDY; MALE; OBSERVATIONAL STUDY; PATIENT SELECTION; SAUDI ARABIA; TREATMENT RESPONSE;

EID: 34547670335     PISSN: 18171737     EISSN: None     Source Type: Journal    
DOI: 10.4103/1817-1737.33696     Document Type: Article

References (17)

1. Global Strategy for Asthma Management and Prevention. Global initiative for Asthma management (GINA) workshop report. NIH Publication No 02-3659; 2005 update. GINA reports are available at www.ginasthma.org
2. Malonne H, Lachman A, Van den Brande P. Impact of montelukast on symptoms in mild-to-moderate persistent asthma and exercise-induced asthma: Results of the ASTHMA survey. Adding Singulair Treatment to handle symptoms in mild to moderate asthmatics. Curr Med Res Opin 2002;18:512-9.
3. Bisgaard H. Role of Leukotrienes in asthma pathophysiology. Pediatr Pulmonol 2000;30:166-76.
4. Dupont L, Potvin E, Korn D, Lachman A, Dramaix M, Gusman J, et al. Improving asthma control in patients suboptimally controlled on inhaled steroids and long-acting beta2-agonists: Addition of montelukast in an open-label pilot study. Curr Med Res Opin 2005;21:863-9.
5. Devillier P, Baccard N, Advenier C. Leukotrienes, leukotriene receptor antagonists and leukotriene synthesis inhibitors in asthma: An update. Part II: Clinical studies with leukotriene receptor antagonists and leukotriene synthesis inhibitors in asthma. Pharmacol Res 1999;40:15-29.
6. O'Shaughnessy K, Wellings R, Gillies B, Fuller RW. Differential effects of fluticasone propionate on allergen-evoked bronchoconstriction and increased urinary leukotriene E4 excretion. Am Rev Respir Dis 1993;147:1472-6.
7. Dworski R, Fitzgerald GA, Oates JA, Sheller JR. Effect of oral prednisone on airway inflammatory mediators in atopic asthma. Am J Respir Crit Care Med 1994;149:953-9.
8. Pavord I, Ward R, Woltmann G, Wardlaw AJ, Sheller JR, Dworski R. Induced sputum eicosanoid concentrations in asthma. Am J Respir Crit Care Med 1999;160:1905-9.
9. Bisgaard H. Role of Leukotrienes in asthma pathophysiology. Pediatr Pulmonol 2000;30:166-76.
10. Luis R, Lau L, Bron A, Roldaan A, Radermeker M, Djukanovi R. The relationship between airways inflammation and asthma severity. Am J Respir Crit Care Med 2000;161:9-16.
11. Pavord L, Ward R, Woltmann G, Wardlaw A, Sheller J, Dworski R. Induced sputum eicosanoid concentrations in asthma. Am J Resp Crit Care Med 1999;160:1905-9.
12. Price D, Ryan D, Pearce L, Bride F. The air study: Asthma in real life. Asthma J 1999;4:74-8.
13. Henderson W, Tang L, Chu S, Taso S, Chiang G, Jones F, et al. A role for cysteinyl leukotrienes in airway remodeling in a mouse asthma model. Am J Resp Crit Care Med 2002;165:108-16.
14. Vaquerizo MJ, Casan P, Castillo J, Perpiña M, Sanchis J, Sobradillo V, et al. Effect of montelukast added to inhaled budesonide on control of mild to moderate asthma. Thorax 2003;58:204-11.
15. Bjermer L, Bisgaard H, Bousquet J, Fabbri A, Fabbri LM, Greening A, Haahtela T, et al. Montelukast or salmeterol combined with an inhaled steroid in adult asthma: Design and rationale of a randomized, double-blind comparative study (the IMPACT Investigation of Montelukast as a Partner Agent for Complementary Therapy-trial. Respir Med 2000;94:612-21.
16. Price DB, Hernandez D, Magyar P, Fiterman J, Beeh KM, James IG, et al. Randomized controlled trial of montelukast plus inhaled budesonide versus double dose inhaled budesonide in adult patients with asthma. Thorax 2003;58:211-6.
17. Borderias L, Mincewicz G, Paggiaro P, Guilera M, Sazonov Kocevar V, Taylor SD, et al. Asthma control in patients with asthma and allergic rhinitis receiving add-on montelukast therapy for 12 months: A retrospective observational study. Curr Med Res Opin 2007;23:721-30.