Effect of the aqueous extract of Syzygium cumini on carbon tetrachloride-induced hepatotoxicity in rats

Phytotherapy Research

Volumn 21, Issue 8, 2007, Pages 793-795

  Moresco, Rafael Noal ^a   Sperotto, Rita Leal ^b   Bernardi, Anie Schiavo ^b   Cardoso, Ricardo França ^c   Gomes, Patrícia ^d  

^a FEDERAL UNIVERSITY OF SANTA MARIA   (Brazil)

^b UNIVERSIDADE DE CRUZ ALTA   (Brazil)

^c UNIVERSIDADE LUTERANA DO BRASIL   (Brazil)

^d DEPARTMENT OF FOOD ENGINEERING   (Brazil)

Author keywords

Aqueous extract; Carbon tetrachloride; Enzymes; Hepatoprotective; Liver; Syzygium cumini

Indexed keywords

ALANINE AMINOTRANSFERASE; ASPARTATE AMINOTRANSFERASE; CARBON TETRACHLORIDE; SYZYGIUM CUMINI EXTRACT;

ALANINE AMINOTRANSFERASE BLOOD LEVEL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; ASPARTATE AMINOTRANSFERASE BLOOD LEVEL; CONTROLLED STUDY; DRUG EFFECT; ENZYME ACTIVITY; LIVER PROTECTION; LIVER TOXICITY; MALE; NONHUMAN; RAT; SINGLE DRUG DOSE;

ANIMALS; CARBON TETRACHLORIDE; CARBON TETRACHLORIDE POISONING; EUGENIA; HEPATITIS, TOXIC; MALE; PLANT EXTRACTS; RATS; RATS, WISTAR; WATER;

RATTUS; SYZYGIUM CUMINI;

EID: 34547666952     PISSN: 0951418X     EISSN: 10991573     Source Type: Journal    
DOI: 10.1002/ptr.2158     Document Type: Article

References (10)

1. Abalea V, Cillard J, Dubos MP, Sergent O, Cillard P, Morel I. 1999. Repair of iron-induced DNA oxidation by the flavonoid myricetin in primary rat hepatocyte culture. Free Radic Biol Med 26: 1457-1466.
2. Chaudhuri AKN, Pal S, Gomes A, Bhattacharya S. 1990. Anti-inflammatory and related actions of Syzigium cumini seed extract. Phytother Res 4: 5-10.
3. 4 induced hepatotoxicity. Gen Pharmacol 26: 309-315.
4. Hewawasam RP, Jayatilaka KAPW, Pathirana C, Mudduwa LKB. 2004. Hepatoprotective effect of Epaltes divaricata extract on carbon tetrachloride induced hepatotoxicity in mice. Indian J Med Res 120: 30-34.
5. Jagetia GC, Baliga MS. 2002. Syzigium cumini (Jamun) reduces the radiation-induced DNA damage in the cultured human peripheral blood lymphocytes: a preliminary study. Toxicol Lett 132: 19-25.
6. Ravi K, Ramachandran B, Subramanian S. 2004. Protective effect of Eugenia jambolana seed kernel on tissue antioxidants in streptozotocin-induced diabetic rats. Biol Pharm Bull 27: 1212-1217.
7. Stanely Mainzen Prince P, Kamalakkannan N, Menon VP. 2003. Syzygium cumini seed extracts reduce tissue damage in diabetic rat brain. J Ethnopharmacol 84: 205-209.
8. Stanely Mainzen Prince P, Menon VP, Pari L. 1998. Hypoglycaemic activity of Syzigium cumini seeds: effect on lipid peroxidation in alloxan diabetic rats. J Ethnopharmacol 61: 1-7.
9. Teixeira CC, Pinto LP, Kesslet FHP et al. 1997. The effect of Syzygium cumini (L.) Skeels on post-prandial blood glucose levels in non-diabetic rats and rats with streptozotocin-induced diabetes mellitus. J Ethnopharmacol 56: 209-213.
10. Theresiamma KC, George J, Kuttan R. 1996. Protective effect of curcumin, ellagic acid and bixin on radiation induced toxicity. Indian J Exp Biol 34: 845-847.