Expression of glucose transporter protein-1 (Glut-1) in ocular surface squamous neoplasia

Cornea

Volumn 26, Issue 7, 2007, Pages 826-830

  Gurses, Iclal ^a   Doganay, Selim ^a   Mizrak, Bulent ^a  

^a INONU UNIVERSITY SCHOOL OF MEDICINE   (Turkey)

Author keywords

Conjunctiva; Glucose transporter protein 1; Intraepithelial neoplasia; Ki 67; Squamous cell carcinoma

Indexed keywords

CELL NUCLEUS ANTIGEN; GLUCOSE; GLUCOSE TRANSPORTER 1; KI 67 ANTIGEN; MONOCLONAL ANTIBODY KI 67;

ADULT; AGED; ARTICLE; BASAL CELL CARCINOMA; CANCER INVASION; CELL PROLIFERATION; CLINICAL ARTICLE; CONJUNCTIVA TUMOR; EYE TUMOR; FEMALE; GLUCOSE TRANSPORT; HUMAN; HUMAN CELL; HUMAN TISSUE; IMMUNOCOMPETENT CELL; IMMUNOHISTOCHEMISTRY; IMMUNOREACTIVITY; KNOWLEDGE; LABELING INDEX; LITERATURE; MALE; MEDICINE; OCULAR SURFACE SQUAMOUS NEOPLASIA; PATHOLOGY; PRIORITY JOURNAL; PROTEIN EXPRESSION; SQUAMOUS CELL CARCINOMA; STAINING; UNIVERSITY;

AGED; AGED, 80 AND OVER; CARCINOMA IN SITU; CARCINOMA, BASOSQUAMOUS; CARCINOMA, SQUAMOUS CELL; CONJUNCTIVAL NEOPLASMS; CORNEAL DISEASES; EYE NEOPLASMS; FEMALE; GLUCOSE; GLUCOSE TRANSPORTER TYPE 1; HUMANS; IMMUNOENZYME TECHNIQUES; KI-67 ANTIGEN; MALE; MIDDLE AGED;

EID: 34547666883     PISSN: 02773740     EISSN: None     Source Type: Journal    
DOI: 10.1097/ICO.0b013e3180645814     Document Type: Article

References (22)

1. Basti S, Macsai MS. Ocular surface squamous neoplasia. Cornea. 2003;22:687-704.
2. Jaworski A, Wolffsohn JS, Napper GA. Detection, aetiology and management of conjunctival intraepithelial neoplasia. Ophthalmic Physiol Opt. 2000;20:371-380.
3. Pizzarello LD, Jakobiec FA. Bowen's disease of the conjunctiva: a misomer. In: Jakobiec FA, ed. Ocular Adnexal Tumors. Birmingham, AL: Aesculapius; 1978:553-571.
4. Macheda ML, Rogers S, Best JD. Molecular and cellular regulation of glucose transporter (GLUT) proteins in cancer. J Cell Physiol. 2005;202:654-662.
5. Scheepers A, Joost HG, Schurmann A. The glucose transporter families SGLT and GLUT: molecular basis of normal and aberrant function. J Parenter Enter Nutr. 2004;28:364-371.
6. Pardridge W, Boado R, Farrell C. Brain-type glucose transporter (GLUT1) is selectively localized to the blood-brain barrier. J Biol Chem. 1990;265:18035-18040.
7. Mantych GJ, Hageman GS, Devaskar SU. Characterization of glucose transporter isoforms in the adult and developing human eye. Endocrinology. 1993;133:600-607.
8. Younes M, Brown RW, Mody DR, et al. GLUT1 expression in human breast carcinoma: correlation with known prognostic markers. Anticancer Res. 1995;15:2895-2898.
9. Younes M, Brown RW, Stephenson M, et al. Overexpression of GLUT1 and GLUT3 in stage I nonsmall cell carcinoma is associated with poor survival. Cancer. 1997;80:1046-1051.
10. Haber RS, Rathan A, Weiser KR, et al. GLUT1 glucose transporter expression in colorectal carcinoma: a marker for poor prognosis. Cancer. 1998;83:34-40.
11. Tunc M, Char DH, Crawford B, et al. Intraepithelial and invasive squamous cell carcinoma of the conjunctiva: analysis of 60 cases. Br J Ophthalmol. 1999;83:98-103.
12. Kiire CA, Dhillon B. The aetiology and associations of conjunctival intraepithelial neoplasia. Br J Ophthalmol. 2006;90:109-113.
13. Joost HG, Thorens B. The extended GLUT-family of sugar/polyol transport facilitators: nomenclature, sequence characteristics, and potential function of its novel members. Mol Membr Biol. 2001;18:247-256.
14. Brown GK. Glucose transporters: structure, function and consequences of deficiency. J Inherit Metab Dis. 2000;23:237-246.
15. Kumagai AK, Glaskow BJ, Pardridge WM. GLUT1 glucose transporter expression in the diabetic and nondiabetic human eye. Invest Ophthalmol Vis Sci. 1994;35:2887-2894.
16. Gherzi R, Melioli G, De Luca M, et al. High expression levels of the erytrocytes/brain type glucose transporter (GLUT1) in the basal cells of human eye conjunctiva and oral mucosa reconstituted in culture. Exp Cell Res. 1991;195:230-236.
17. Lu L, Reinach PS, Kao WW-Y. Corneal epithelial wound healing. Exp Biol Med. 2001;226:653-664.
18. Yoshizawa M, Feinberg SE, Marcelo CL, et al. Ex vivo produced human conjunctiva and oral mucosa equivalents grown in a serum-free culture system. J Oral Maxillofac Surg. 2004;62:980-988.
19. Xiuli G, Meiyu G, Guanhua D. Glucose transporter 1, distribution in the brain and in neural disorders: its relationship with transport of neuroactive drugs through the blood-brain barrier. Biochem Genet. 2005;43:175-187.
20. Ohara M, Sotozono C, Tsuchihashi Y, et al. Ki-67 labeling index as a marker of malignancy in ocular surface neoplasms. Jpn J Ophthalmol. 2004;48:524-529.
21. Haedrich CA, Sundmacher R, Spelsberg H, et al. Expression of p63 in conjunctival intraepithelial neoplasia and squamous cell carcinoma. Graefes Arch Clin Exp Ophthalmol. 2006;244:96-103.
22. Jung SM, Lin HC, Chu PH, et al. Expression of cell cycle-regulatory proteins, MIB-1, p16, p53, and p63, in squamous cell carcinoma of conjunctiva: not associated with human papillomavirus infection. Virchows Arch. 2006;448:301-305.