Evaluation of CD11b expression on peripheral blood neutrophils for early detection of neonatal sepsis

Iranian Journal of Allergy, Asthma and Immunology

Volumn 6, Issue 2, 2007, Pages 93-96

  Adib, Minoo ^a   Ostadi, Vajiheh ^a   Navaei, Fakhri ^a   Fosoul, Fereshteh Saheb ^a   Oreizi, Farzad ^a   Shokouhi, Raheleh ^b   Bakhshiani, Zahra ^a  

^a ISFAHAN UNIVERSITY OF MEDICAL SCIENCES   (Iran)

^b UNIVERSITY OF TEHRAN   (Iran)

Author keywords

Cd11b; CR3; Neonatal sepsis; Neutrophils

Indexed keywords

C REACTIVE PROTEIN; CD11B ANTIGEN;

ANTIGEN EXPRESSION; ARTICLE; BLOOD CULTURE; BLOOD SAMPLING; CLASSIFICATION; CONTROLLED STUDY; DIAGNOSTIC ACCURACY; DIAGNOSTIC VALUE; DISEASE COURSE; EARLY DIAGNOSIS; FLOW CYTOMETRY; GESTATIONAL AGE; HUMAN; INFECTION; MAJOR CLINICAL STUDY; NEUTROPHIL; NEWBORN; NEWBORN SEPSIS; PREDICTION; QUANTITATIVE ANALYSIS; SENSITIVITY AND SPECIFICITY; SYMPTOM;

ANTIGENS, CD11B; ANTIGENS, CD18; C-REACTIVE PROTEIN; EARLY DIAGNOSIS; HUMANS; INFANT; INFANT, NEWBORN; INTERLEUKIN-8; LEUKOCYTE COUNT; NEUTROPHILS; SENSITIVITY AND SPECIFICITY; SEPSIS;

EID: 34547646741     PISSN: 17351502     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article

References (17)

1. Cole FS. Bacterial Infections of the Newborn. In: Tacusch HW, Ballard RA, editors. Avery's disease of the newborn. Philadelphia: WB Sunders Co. 1998: 490-512.
2. Avroy A, Fanaroff RY. Neonatal- Perinatal Medicine: Diseases of the Fetus and Infant. USA, Lowis: Mosby, 2002: 360-91.
3. Nupponen I, Andersson S, Jarvenpaa AL, Kautiainen H, Repo H. Neutrophil CD11b expression and circulating interleukin-8 as diagnostic markers for early-onset neonatal sepsis. Pediatrics 2001; 108(1):E12.
4. Espinosa EL, Gonzalez LFP, Montes AT. Expression of CD64 as a potential marker of neonatal sepsis. Pediatr Allergy Immunol 2002; 13:319-27.
5. Turunen R, Andersson S, Nupponen I, Kautiainen H, Siitonen S, Repo H. Increased CD11b-density on circulating phagocytes as an early sign of late-onset sepsis in extremely low-birthweight infants. Pediatr Res 2005; 57(2):270-5.
6. Dollner H, Vatten L. Austgulen R. Early diagnostic markers for neonatal sepsis: comparing C-reactive protein, interleukin-6, soluble tumour necrosis factor receptors and soluble adhesion molecules. J Clin Epidemiol 2001; 54(12):1251-7.
7. Volanakis JE. Human C-reactive protein: expression, structure, and function. Mol Immunol 2001; 38(2-3):189-97.
8. Clyne B, Olshaker JS. The C-Reactive Protein. J Emerg Med 1999; 17(6):1019-25.
9. Ng PC. Diagnostic markers for neonatal sepsis. Curr Opin Pediatr 2006; 18(2):125-31.
10. Weirich E, Rabin RL, Maldonado Y, Benitz W, Modler S, Herzenberg LA, Herzenberg LA. Neutrophil CD11b expression as a diagnostic marker for early-onset neonatal infection. J Pediatr 1998; 132(3 Pt 1):445-51.
11. Horns KM. Neoteric physiologic and immunologic methods for assessing early-onset neonatal sepsis. J Perinat Neonatal Nurs 2000; 13(4):50-66.
12. Lehr HA, Krombach F, Munzing S, Bodlaj R, Glaubitt SI, Seiffge D, et al. In vitro effects of oxidized low density lipoprotein on CD11b/CD18 and L-selectin presentation on neutrophils and monocytes with relevance for the in vivo situation. Am J Pathol 1995; 146(1):218-27.
13. Simms HH, D'Amico R. Lipopolysaccharide induces intracytoplasmic migration of the polymorphonuclear leukocyte CD11b/CD18 receptor. Shock 1995; 3(3):196-203. .
14. McKenney WM. Understanding the neonatal immune system: high risk for infection. Crit Care Nurse 2001; 21(6):35-47.
15. Ng PC, Cheng SH, Chui KM, Fok TF, Wong MY, Wong W, et al. Diagnosis of late onset neonatal sepsis with cytokines, adhesion molecule, and C-reactive protein in preterm very low birthweight infants. Arch Dis Child Fetal Neonatal Ed 1997; 77(3):F221-7.
16. Cui YB, Du LZ, Chen YZ, Yu YB, Wang FM, Mao QQ. Expression of neutrophil adhesion molecule CD11b as an early diagnostic marker for neonatal sepsis. Zhonghua Er Ke Za Zhi 2003; 41(5):348-51.
17. Ng PC, Li K, Wong RP, Chui KM, Wong E, Fok TF. Neutrophil CD64 expression: a sensitive diagnostic marker for late-onset nosocomial infection in very low birthweight infants. Pediatr Res 2002; 51(3):296-303.