Sustained contraction at very low forces produces prominent supraspinal fatigue in human elbow flexor muscles

Journal of Applied Physiology

Volumn 103, Issue 2, 2007, Pages 560-568

  Smith, Janette L ^a   Martin, Peter G ^a   Gandevia, Simon C ^a   Taylor, Janet L ^a,b  

^a UNIVERSITY OF NEW SOUTH WALES   (Australia)

^b NEUROSCIENCE RESEARCH AUSTRALIA   (Australia)

Author keywords

Central fatigue; Effort; Submaximal; Transcranial magnetic stimulation; Voluntary activation

Indexed keywords

ADULT; ARTICLE; BICEPS BRACHII MUSCLE; BRACHIAL PLEXUS; CLINICAL ARTICLE; ELBOW FLEXION; ELECTROMYOGRAM; FEMALE; HUMAN; MALE; MOTOR CORTEX; MUSCLE EXCITATION; MUSCLE FATIGUE; MUSCLE FUNCTION; MUSCLE ISOMETRIC CONTRACTION; PRIORITY JOURNAL; TORQUE;

ADULT; ELBOW; ELECTRIC STIMULATION; ELECTROMYOGRAPHY; FEMALE; HUMANS; MALE; MIDDLE AGED; MOTOR CORTEX; MUSCLE CONTRACTION; MUSCLE FATIGUE; MUSCLE, SKELETAL; SPINE;

EID: 34547642304     PISSN: 87507587     EISSN: 15221601     Source Type: Journal    
DOI: 10.1152/japplphysiol.00220.2007     Document Type: Article

References (48)

1. Adam A, De Luca CJ. Firing rates of motor units in human vastus lateralis muscle during fatiguing isometric contractions. J Appl Physiol 99: 268-280, 2005.
2. Allen GM, Gandevia SC, McKenzie DK. Reliability of measurements of muscle strength and voluntary activation using twitch interpolation. Muscle Nerve 18: 593-600, 1995.
3. Allen GM, McKenzie DK, Gandevia SC. Twitch interpolation of the elbow flexor muscles at high forces. Muscle Nerve 21: 318-328, 1998.
4. Belanger AY, McComas AJ. Extent of motor unit activation during effort. J Appl Physiol 51: 1131-1135, 1981.
5. Benwell NM, Sacco P, Hammond GR, Byrnes ML, Mastaglia FL, Thickbroom GW. Short-interval cortical inhibition and corticomotor excitability with fatiguing hand exercise: a central adaptation to fatigue? Exp Brain Res 170: 191-198, 2006.
6. Bigland-Ritchie B, Cafarelli E, Vollestad NK. Fatigue of submaximal static contractions. Acta Physiol Scand 128, Suppl 556: 137-148, 1986.
7. Bigland-Ritchie B, Woods JJ. Changes in muscle contractile properties and neural control during human muscular fatigue. Muscle Nerve 7: 691-699, 1984.
8. Blangsted AK, Vedsted P, Sjogaard G, Sogaard K. Intramuscular pressure and tissue oxygenation during low-force static contraction do not underlie muscle fatigue. Acta Physiol Scand 183: 379-388, 2005.
9. Blangsted AK, Sjogaard G, Madeleine P, Olsen HB, Sogaard K. Voluntary low-force contraction elicits prolonged low-frequency fatigue and changes in surface electromyography and mechanomyography. J Electromyog Kinesiol 15: 138-148, 2005.
10. Bongiovanni LG, Hagbarth KE. Tonic vibration reflexes elicited during fatigue from maximal voluntary contractions in man. J Physiol 423: 1-14, 1990.
11. Borg G, Ljunggren G, Ceci R. The increase of perceived exertion, aches and pain in the legs, heart rate and blood lactate during exercise on a bicycle ergometer. Eur J Appl Physiol 54: 343-349, 1985.
12. Butler JE, Taylor JL, Gandevia SC. Responses of human motoneurons to corticospinal stimulation during maximal voluntary contractions and ischemia. J Neurosci 23: 10224-10230, 2003.
13. Di Lazzaro V, Restuccia D, Oliviero A, Profice P, Ferrara L, Insola A, Mazzone P, Tonali P, Rothwell JC. Effects of voluntary contraction on descending volleys evoked by transcranial stimulation in conscious humans. J Physiol 508: 625-633, 1998.
14. Dorfman LJ, Howard JE, McGill KC. Triphasic behavioral response of motor units to submaximal fatiguing exercise. Muscle Nerve 13: 621-628, 1990.
15. Gandevia SC. Spinal and supraspinal factors in human muscle fatigue. Physiol Rev 81: 1725-1789, 2001.
16. Gandevia SC, Allen GM, Butler JE, Taylor JL. Supraspinal factors in human muscle fatigue: evidence for suboptimal output from the motor cortex. J Physiol 490: 529-536, 1996.
17. Hess CW, Mills KR, Murray NMF. Responses in small hand muscles from magnetic stimulation of the human brain. J Physiol 388: 397-419, 1987.
18. Inghilleri M, Berardelli A, Cruccu G, Manfredi M. Silent period evoked by transcranial stimulation of the human cortex and cervicomedullary junction. J Physiol 466: 521-534, 1993.
19. Johnson KVB, Edwards SC, van Tongeren C, Bawa P. Properties of human motor units after prolonged activity at a constant firing rate. Exp Brain Res 154: 479-487, 2004.
20. Kernell D, Monster AW. Motoneurone properties and motor fatigue: an intracellular study of gastrocnemius motoneurones of the cat. Exp Brain Res 46: 197-204, 1982.
21. Kouzaki M, Shinohara M. The frequency of alternate muscle activity is associated with the attenuation in muscle fatigue. J Appl Physiol 101: 715-720, 2006.
22. Kouzaki M, Shinohara M, Masani K, Fukunaga T. Force fluctuations are modulated by alternate muscle activity of knee extensor synergists during low-level sustained contraction. J Appl Physiol 97: 2121-2131, 2004.
23. Kouzaki M, Shinohara M, Masani K, Kanehisa H, Fukunaga T. Alternate muscle activity observed between knee extensor synergists during low-level sustained contractions. J Appl Physiol 93: 675-684, 2002.
24. Kouzaki M, Shinohara M, Masani K, Tachi M, Kanehisa H, Fukunaga T. Local blood circulation among knee extensor synergists in relation to alternate muscle activity during low-level sustained contraction. J Appl Physiol 95: 49-56, 2003.
25. Krogh-Lund C. Myo-electric fatigue and force failure from submaximal static elbow flexion sustained to exhaustion. Eur J Appl Physiol Occup Physiol 67: 389-401, 1993.
26. Kuchinad RA, Ivanova TD, Garland SJ. Modulation of motor unit discharge rate and H-reflex amplitude during submaximal fatigue of the human soleus muscle. Exp Brain Res 158: 345-355, 2004.
27. Le Pera D, Graven-Nielsen T, Valeriani M, Oliviero A, Di Lazzaro V, Tonali PA, Arendt-Nielsen L. Inhibition of motor system excitability at cortical and spinal level by tonic muscle pain. Clin Neurophysiol 112: 1633-1641, 2001.
28. Macefield G, Hagbarth KE, Gorman RB, Gandevia SC, Burke D. Decline in spindle support to α-motoneurones during sustained voluntary contractions. J Physiol 440: 497-512, 1991.
29. Martin PG, Smith JL, Butler JE, Gandevia SC, Taylor JL. Fatigue-sensitive afferents inhibit extensor but not flexor motoneurons in humans. J Neurosci 26: 4796-4802, 2006.
30. McKay WB, Dobrivoje SS, Sherwood AM, Vrbova G, Dimitrijevic MR. Effect of fatiguing maximal voluntary contraction on excitatory and inhibitory responses elicited by transcranial magnetic motor cortex stimulation. Muscle Nerve 19: 1017-1024, 1996.
31. McKenzie DK, Bigland-Ritchie B, Gorman RB, Gandevia SC. Central and peripheral fatigue of the human diaphragm and limb muscles assessed by twitch interpolation. J Physiol 454: 643-656, 1992.
32. Merton PA. Voluntary strength and fatigue. J Physiol 123: 553-564, 1954.
33. Pettorossi VE, Torre GD, Bortolami R, Brunetti O. The role of capsaicin-sensitive muscle afferents in fatigue-induced modulation of the monosynaptic reflex in the rat. J Physiol 515: 599-607, 1999.
34. Rohmert W. Determination of the recovery pause for static work of man. Int Z Angew Physiol Einschl Arbeitsphysiol 18: 123-164, 1960.
35. Rosendal L, Blangsted AK, Kristiansen J, Søgaard K, Langberg H, Sjøgaard G, Kjaer M. Interstitial muscle lactate, pyruvate and potassium dynamics in the trapezius muscle during repetitive low-force arm movements, measured with microdialysis. Acta Physiol Scand 182: 379-388, 2004.
36. Rosendal L, Kristiansen J, Gerdle B, Sogaard K, Peolsson M, Kjaer M, Sorensen J, Larsson B. Increased levels of interstitial potassium but normal levels of muscle IL-6 and LDH in patients with trapezius myalgia. Pain 119: 201-209, 2005.
37. Sacco P, Hope PAJ, Thickbroom GW, Byrnes ML, Mastaglia FL. Corticomotor excitability and perception of effort during sustained exercise in the chronic fatigue syndrome. Clin Neurophysiol 110: 1883-1891, 1999.
38. Sjøgaard G, Kiens B, Jorgensen K, Saltin B. Intramuscular pressure, EMG and blood flow during low-level prolonged static contraction in man. Acta Physiol Scand 128: 475-484, 1986.
39. Søgaard K, Gandevia SC, Todd G, Petersen NT, Taylor JL. The effect of sustained low-intensity contractions on supraspinal fatigue in human elbow flexor muscles. J Physiol 573: 511-523, 2006.
40. Taylor JL, Allen GM, Butler JE, Gandevia SC. Supraspinal fatigue during intermittent maximal voluntary contractions of the human elbow flexors. J Appl Physiol 89: 305-313, 2000.
41. Taylor JL, Butler JE, Allen GM, Gandevia SC. Changes in motor cortical excitability during human muscle fatigue. J Physiol 490: 519-528, 1996.
42. Taylor JL, Petersen NT, Butler JE, Gandevia SC. Interaction of transcranial magnetic stimulation and electrical transmastoid stimulation in human subjects. J Physiol 541: 949-958, 2002.
43. Taylor JL, Petersen NT, Butler JE, Gandevia SC. Ischaemia after exercise does not reduce responses of human motoneurones to cortical or corticospinal tract stimulation. J Physiol 525: 793-801, 2000.
44. Taylor JL, Todd G, Gandevia SC. Evidence for a supraspinal contribution to human muscle fatigue. Clin Exp Pharmacol Physiol 33: 400-405, 2006.
45. Todd G, Butler JE, Taylor JL, Gandevia SC. Hyperthermia: a failure of the motor cortex and the muscle. J Physiol 563: 621-631, 2005.
46. Todd G, Taylor JL, Gandevia SC. Measurement of voluntary activation of fresh and fatigued human muscles using transcranial magnetic stimulation. J Physiol 551: 661-671, 2003.
47. Todd G, Taylor JL, Gandevia SC. Reproducible measurement of voluntary activation of human elbow flexors with motor cortical stimulation. J Appl Physiol 97: 236-242, 2004.
48. Ugawa Y, Terao Y, Hanajima R, Sakai K, Kanazawa I. Facilitatory effect of tonic voluntary contraction on responses to motor cortex stimulation. Electroencephalogr Clin Neurophysiol 97: 451-454, 1995.