메뉴 건너뛰기




Volumn 18, Issue 8, 2007, Pages 2242-2251

Frontiers in nephrology: Immune tolerance to allografts in humans

Author keywords

[No Author keywords available]

Indexed keywords

AZATHIOPRINE; B7 ANTIGEN; CD28 ANTIGEN; CD86 ANTIGEN; GLUCOCORTICOID; IMMUNOSUPPRESSIVE AGENT; STEROID;

EID: 34547641365     PISSN: 10466673     EISSN: None     Source Type: Journal    
DOI: 10.1681/ASN.2007020180     Document Type: Review
Times cited : (39)

References (130)
  • 1
    • 85190641824 scopus 로고    scopus 로고
    • Gaspare Tagliacozzi (1545-1599): Surgical Implants for Mutilations, edited by Gaspace Bindoni the Younger, Venice, 1597
    • Gaspare Tagliacozzi (1545-1599): Surgical Implants for Mutilations, edited by Gaspace Bindoni the Younger, Venice, 1597
  • 2
    • 0037693554 scopus 로고
    • Is iso-skin grafting practicable?
    • Padgett ECM: Is iso-skin grafting practicable? South Med J 25: 895-900, 1932
    • (1932) South Med J , vol.25 , pp. 895-900
    • Padgett, E.C.M.1
  • 3
    • 0001078867 scopus 로고
    • Homografting of skin: With report of success in identical twins
    • Brown JB: Homografting of skin: With report of success in identical twins. Surgery 1: 558-563, 1937
    • (1937) Surgery , vol.1 , pp. 558-563
    • Brown, J.B.1
  • 4
    • 0005984244 scopus 로고
    • Actively acquired tolerance of foreign cells
    • Billingham RE, Brent L, Medawar PB: "Actively acquired" tolerance of foreign cells. Nature 172: 603-606, 1953
    • (1953) Nature , vol.172 , pp. 603-606
    • Billingham, R.E.1    Brent, L.2    Medawar, P.B.3
  • 8
    • 0030896219 scopus 로고    scopus 로고
    • Stable mixed hematopoietic chimerism in DLA-identical littermate dogs given sublethal total body irradiation before and pharmacological immunosuppression after marrow transplantation
    • Storb R, Yu C, Wagner JL, Deeg HJ, Nash RA, Kiem HP, Leisenring W, Shulman H: Stable mixed hematopoietic chimerism in DLA-identical littermate dogs given sublethal total body irradiation before and pharmacological immunosuppression after marrow transplantation. Blood 89: 3048-3054, 1997
    • (1997) Blood , vol.89 , pp. 3048-3054
    • Storb, R.1    Yu, C.2    Wagner, J.L.3    Deeg, H.J.4    Nash, R.A.5    Kiem, H.P.6    Leisenring, W.7    Shulman, H.8
  • 10
    • 33745235090 scopus 로고    scopus 로고
    • Transplant tolerance in non-human primates: Progress, current challenges and unmet needs
    • Kean LS, Gangappa S, Pearson TC, Larsen CP: Transplant tolerance in non-human primates: Progress, current challenges and unmet needs. Am J Transplant 6: 884-893, 2006
    • (2006) Am J Transplant , vol.6 , pp. 884-893
    • Kean, L.S.1    Gangappa, S.2    Pearson, T.C.3    Larsen, C.P.4
  • 11
    • 0344121735 scopus 로고    scopus 로고
    • Crossing the bridge: Large animal models in translational transplantation research
    • Kirk AD: Crossing the bridge: Large animal models in translational transplantation research. Immunol Rev 196: 176-196, 2003
    • (2003) Immunol Rev , vol.196 , pp. 176-196
    • Kirk, A.D.1
  • 13
    • 0020051265 scopus 로고
    • Psoriasis in monozygotic twins: Variations in expression in individuals with identical genetic constitution
    • Brandrup F, Holm N, Grunnet N, Henningsen K, Hansen HE: Psoriasis in monozygotic twins: Variations in expression in individuals with identical genetic constitution. Acta Derm Venereol 62: 229-236, 1982
    • (1982) Acta Derm Venereol , vol.62 , pp. 229-236
    • Brandrup, F.1    Holm, N.2    Grunnet, N.3    Henningsen, K.4    Hansen, H.E.5
  • 17
    • 0039434587 scopus 로고    scopus 로고
    • Richmond, VA, United Network for Organ Sharing. Available at:, Accessed December 14, 2006
    • United Network for Organ Sharing: Data, Richmond, VA, United Network for Organ Sharing. Available at: www.unos.org/data. Accessed December 14, 2006
    • United Network for Organ Sharing: Data
  • 18
    • 33745804056 scopus 로고    scopus 로고
    • An appraisal of tolerance in liver transplantation
    • Lerut J, Sanchez-Fueyo A: An appraisal of tolerance in liver transplantation. Am J Transplant 6: 1774-1780, 2006
    • (2006) Am J Transplant , vol.6 , pp. 1774-1780
    • Lerut, J.1    Sanchez-Fueyo, A.2
  • 21
    • 33846224315 scopus 로고    scopus 로고
    • Prope' tolerance in a noncompliant living related small bowel transplant recipient after severe rejection
    • Asolati M, Testa G, Gangemi A, Sankary H, Oberholzer J, Benedetti E: 'Prope' tolerance in a noncompliant living related small bowel transplant recipient after severe rejection. Transplantation 83: 77-79, 2007
    • (2007) Transplantation , vol.83 , pp. 77-79
    • Asolati, M.1    Testa, G.2    Gangemi, A.3    Sankary, H.4    Oberholzer, J.5    Benedetti, E.6
  • 22
    • 0018971852 scopus 로고
    • Cessation of immunosuppressive therapy after successful transplantation: A national survey
    • Zoller KM: Cessation of immunosuppressive therapy after successful transplantation: A national survey. Kidney Int 18: 110-114, 1980
    • (1980) Kidney Int , vol.18 , pp. 110-114
    • Zoller, K.M.1
  • 25
    • 0037531635 scopus 로고    scopus 로고
    • Dendritic cell subset ratio in peripheral blood correlates with successful withdrawal of immunosuppression in liver transplant patients
    • Mazariegos GV, Zahorchak AF, Reyes J, Ostrowski L, Flynn B, Zeevi A, Thomson AW: Dendritic cell subset ratio in peripheral blood correlates with successful withdrawal of immunosuppression in liver transplant patients. Am J Transplant 3: 689-696, 2003
    • (2003) Am J Transplant , vol.3 , pp. 689-696
    • Mazariegos, G.V.1    Zahorchak, A.F.2    Reyes, J.3    Ostrowski, L.4    Flynn, B.5    Zeevi, A.6    Thomson, A.W.7
  • 26
    • 33644774902 scopus 로고    scopus 로고
    • Meteorology and tolerance
    • Kirk AD: Meteorology and tolerance. Am J Transplant 6: 645-646, 2006
    • (2006) Am J Transplant , vol.6 , pp. 645-646
    • Kirk, A.D.1
  • 29
    • 0024364744 scopus 로고
    • Acquired immune tolerance to cadaveric renal allografts. A study of three patients treated with total lymphoid irradiation
    • Strober S: Acquired immune tolerance to cadaveric renal allografts. A study of three patients treated with total lymphoid irradiation. N Engl J Med 321: 28-33, 1989
    • (1989) N Engl J Med , vol.321 , pp. 28-33
    • Strober, S.1
  • 30
    • 20344366308 scopus 로고    scopus 로고
    • Long-term outcome of immunosuppression withdrawal after liver transplantation
    • Girlanda R, Rela M, Williams R, O'Grady JG, Heaton ND: Long-term outcome of immunosuppression withdrawal after liver transplantation. Transplant Proc 37: 1708-1709, 2005
    • (2005) Transplant Proc , vol.37 , pp. 1708-1709
    • Girlanda, R.1    Rela, M.2    Williams, R.3    O'Grady, J.G.4    Heaton, N.D.5
  • 31
    • 0019302736 scopus 로고
    • Transplantation tolerance in primates following total lymphoid irradiation and allogeneic bone marrow injection. II. Renal allografts
    • Myburgh JA, Smit JA, Hill RR, Browde S: Transplantation tolerance in primates following total lymphoid irradiation and allogeneic bone marrow injection. II. Renal allografts. Transplantation 29: 405-408, 1980
    • (1980) Transplantation , vol.29 , pp. 405-408
    • Myburgh, J.A.1    Smit, J.A.2    Hill, R.R.3    Browde, S.4
  • 33
    • 0032997619 scopus 로고    scopus 로고
    • T cell costimulatory blockade: New therapies for transplant rejection
    • Gudmundsdottir H, Turka LA: T cell costimulatory blockade: New therapies for transplant rejection. J Am Soc Nephrol 10: 1356-1365, 1999
    • (1999) J Am Soc Nephrol , vol.10 , pp. 1356-1365
    • Gudmundsdottir, H.1    Turka, L.A.2
  • 34
    • 0032812974 scopus 로고    scopus 로고
    • Transplantation tolerance: The concept and its applicability
    • Dong VM, Womer KL, Sayegh MH: Transplantation tolerance: The concept and its applicability. Pediatr Transplant 3: 181-192, 1999
    • (1999) Pediatr Transplant , vol.3 , pp. 181-192
    • Dong, V.M.1    Womer, K.L.2    Sayegh, M.H.3
  • 35
    • 1842452032 scopus 로고    scopus 로고
    • Induction of tolerance
    • Thomas W, Megan S: Induction of tolerance. Surgery 135: 359-364, 2004
    • (2004) Surgery , vol.135 , pp. 359-364
    • Thomas, W.1    Megan, S.2
  • 36
    • 1842577479 scopus 로고    scopus 로고
    • Ethics in the quest for transplant tolerance
    • Kirk AD: Ethics in the quest for transplant tolerance. Transplantation 77: 947-951, 2004
    • (2004) Transplantation , vol.77 , pp. 947-951
    • Kirk, A.D.1
  • 37
    • 33748702266 scopus 로고    scopus 로고
    • Induction immunosuppression
    • Kirk AD: Induction immunosuppression. Transplantation 82: 593-602, 2006
    • (2006) Transplantation , vol.82 , pp. 593-602
    • Kirk, A.D.1
  • 38
    • 0035025762 scopus 로고    scopus 로고
    • Mixed chimerism and transplant tolerance
    • Sykes M: Mixed chimerism and transplant tolerance. Immunity 14: 417-424, 2001
    • (2001) Immunity , vol.14 , pp. 417-424
    • Sykes, M.1
  • 39
    • 0030973944 scopus 로고    scopus 로고
    • Progress toward tolerance and xenografting
    • Roy Calne S: Progress toward tolerance and xenografting. Transplant Proc 29: 16-18, 1997
    • (1997) Transplant Proc , vol.29 , pp. 16-18
    • Roy Calne, S.1
  • 40
    • 0345183785 scopus 로고
    • The reversal of rejection in human renal homografts with subsequent development of homograft tolerance
    • Starzl TE, Marchioro TL, Wadell WR: The reversal of rejection in human renal homografts with subsequent development of homograft tolerance. Surg Gynecol Obstet 117: 385-395, 1963
    • (1963) Surg Gynecol Obstet , vol.117 , pp. 385-395
    • Starzl, T.E.1    Marchioro, T.L.2    Wadell, W.R.3
  • 43
    • 0038171458 scopus 로고    scopus 로고
    • Activation-induced cell death in T cells
    • Green DR, Droin N, Pinkoski M: Activation-induced cell death in T cells. Immunol Rev 193: 70-81, 2003
    • (2003) Immunol Rev , vol.193 , pp. 70-81
    • Green, D.R.1    Droin, N.2    Pinkoski, M.3
  • 44
    • 0344613988 scopus 로고    scopus 로고
    • Blocking both signal 1 and signal 2 of T-cell activation prevents apoptosis of alloreactive T cells and induction of peripheral allograft tolerance
    • Li Y, Li XC, Zheng XX, Wells AD, Turka LA, Strom TB: Blocking both signal 1 and signal 2 of T-cell activation prevents apoptosis of alloreactive T cells and induction of peripheral allograft tolerance. Nat Med 5: 1298-1302, 1999
    • (1999) Nat Med , vol.5 , pp. 1298-1302
    • Li, Y.1    Li, X.C.2    Zheng, X.X.3    Wells, A.D.4    Turka, L.A.5    Strom, T.B.6
  • 48
    • 0015595810 scopus 로고
    • Effect of blood transfusions on subsequent kidney transplants
    • Opelz G: Effect of blood transfusions on subsequent kidney transplants. Transplant Proc 5: 253-259, 1973
    • (1973) Transplant Proc , vol.5 , pp. 253-259
    • Opelz, G.1
  • 49
    • 0029626656 scopus 로고
    • Donor-specific transfusions have long-term beneficial effects for human renal allografts
    • Flye MW: Donor-specific transfusions have long-term beneficial effects for human renal allografts. Transplantation 60: 1395-1401, 1995
    • (1995) Transplantation , vol.60 , pp. 1395-1401
    • Flye, M.W.1
  • 50
    • 0017080404 scopus 로고
    • Possible active enhancement of a human cadaver renal allograft with antilymphocyte serum (ALS) and donor bone marrow: Case report of an initial attempt
    • Monaco AP: Possible active enhancement of a human cadaver renal allograft with antilymphocyte serum (ALS) and donor bone marrow: Case report of an initial attempt. Surgery 79: 384-392, 1976
    • (1976) Surgery , vol.79 , pp. 384-392
    • Monaco, A.P.1
  • 51
    • 0026080585 scopus 로고
    • Long-term results of a controlled prospective study with transfusion of donor-specific bone marrow in 57 cadaveric renal allograft recipients
    • Barber WH: Long-term results of a controlled prospective study with transfusion of donor-specific bone marrow in 57 cadaveric renal allograft recipients. Transplantation 51: 70-75, 1991
    • (1991) Transplantation , vol.51 , pp. 70-75
    • Barber, W.H.1
  • 56
    • 5144225088 scopus 로고    scopus 로고
    • Chimerism and tolerance in transplantation
    • Starzl TE: Chimerism and tolerance in transplantation. Proc Natl Acad Sci U S A 101: 14607-14614, 2004
    • (2004) Proc Natl Acad Sci U S A , vol.101 , pp. 14607-14614
    • Starzl, T.E.1
  • 59
    • 0035124189 scopus 로고    scopus 로고
    • Mixed chimerism and transplantation tolerance
    • Wekerle T, Sykes M: Mixed chimerism and transplantation tolerance. Annu Rev Med 52: 353-370, 2001
    • (2001) Annu Rev Med , vol.52 , pp. 353-370
    • Wekerle, T.1    Sykes, M.2
  • 60
    • 0037955550 scopus 로고    scopus 로고
    • Chimerism in organ transplantation: Conflicting experiments and clinical observations
    • Monaco AP, Medawar P: Chimerism in organ transplantation: Conflicting experiments and clinical observations. Transplantation 75: 13S-16S, 2003
    • (2003) Transplantation , vol.75
    • Monaco, A.P.1    Medawar, P.2
  • 61
    • 0025855941 scopus 로고
    • Immunologic tolerance to renal allografts after bone marrow transplants from the same donors
    • Sayegh MH: Immunologic tolerance to renal allografts after bone marrow transplants from the same donors. Ann Intern Med 114: 954-955, 1991
    • (1991) Ann Intern Med , vol.114 , pp. 954-955
    • Sayegh, M.H.1
  • 62
    • 0028560026 scopus 로고
    • Renal transplantation without immunosuppression in a host with tolerance induced by allogeneic bone marrow transplantation
    • Helg C: Renal transplantation without immunosuppression in a host with tolerance induced by allogeneic bone marrow transplantation. Transplantation 58: 1420-1422, 1994
    • (1994) Transplantation , vol.58 , pp. 1420-1422
    • Helg, C.1
  • 63
    • 0029033078 scopus 로고
    • Renal transplantation without chronic immunosuppression after T cell-depleted, HLA-mismatched bone marrow transplantation
    • Sorof JM: Renal transplantation without chronic immunosuppression after T cell-depleted, HLA-mismatched bone marrow transplantation. Transplantation 59: 1633-1635, 1995
    • (1995) Transplantation , vol.59 , pp. 1633-1635
    • Sorof, J.M.1
  • 64
    • 0032814930 scopus 로고    scopus 로고
    • Renal transplantation for end-stage renal disease following bone marrow transplantation: A report of six cases, with and without immunosuppression
    • Butcher JA, Hariharan S, Adams MB, Johnson CP, Roza AM, Cohen EP: Renal transplantation for end-stage renal disease following bone marrow transplantation: A report of six cases, with and without immunosuppression. Clin Transplant 13: 330-335, 1999
    • (1999) Clin Transplant , vol.13 , pp. 330-335
    • Butcher, J.A.1    Hariharan, S.2    Adams, M.B.3    Johnson, C.P.4    Roza, A.M.5    Cohen, E.P.6
  • 65
    • 0031658155 scopus 로고    scopus 로고
    • Outcomes of recipients of both bone marrow and solid organ transplants: A review
    • Dey BM, Sykes MM, Spitzer TRM: Outcomes of recipients of both bone marrow and solid organ transplants: A review. Medicine 77: 355-369, 1998
    • (1998) Medicine , vol.77 , pp. 355-369
    • Dey, B.M.1    Sykes, M.M.2    Spitzer, T.R.M.3
  • 66
    • 23444459237 scopus 로고
    • Tolerance to an HLA-B, DR disparate kidney allograft after bone-marrow transplantation from same donor
    • Jacobsen N, Taaning E, Ladefoged J, Kvist Kristensen J, Pedersen F: Tolerance to an HLA-B, DR disparate kidney allograft after bone-marrow transplantation from same donor. Lancet 343: 800, 1994
    • (1994) Lancet , vol.343 , pp. 800
    • Jacobsen, N.1    Taaning, E.2    Ladefoged, J.3    Kvist Kristensen, J.4    Pedersen, F.5
  • 67
    • 0021845739 scopus 로고
    • Characterization of mixed allogeneic chimeras. Immunocompetence, in vitro reactivity, and genetic specificity of tolerance
    • Ildstad ST, Wren SM, Bluestone JA, Barbieri SA, Sachs DH: Characterization of mixed allogeneic chimeras. Immunocompetence, in vitro reactivity, and genetic specificity of tolerance. J Exp Med 162: 231-244, 1985
    • (1985) J Exp Med , vol.162 , pp. 231-244
    • Ildstad, S.T.1    Wren, S.M.2    Bluestone, J.A.3    Barbieri, S.A.4    Sachs, D.H.5
  • 68
    • 0030752411 scopus 로고    scopus 로고
    • Induction of high levels of allogeneic hematopoietic reconstitution and donor-specific tolerance without myelosuppressive conditioning
    • Sykes M, Szot GL, Swenson KA, Pearson DA: Induction of high levels of allogeneic hematopoietic reconstitution and donor-specific tolerance without myelosuppressive conditioning. Nat Med 3: 783-787, 1997
    • (1997) Nat Med , vol.3 , pp. 783-787
    • Sykes, M.1    Szot, G.L.2    Swenson, K.A.3    Pearson, D.A.4
  • 69
    • 21244483043 scopus 로고    scopus 로고
    • Roles of deletion and regulation in creating mixed chimerism and allograft tolerance using a nonlymphoablative irradiation-free protocol
    • Domenig C, Sanchez-Fueyo A, Kurtz J, Alexopoulos SP, Mariat C, Sykes M, Strom TB, Zheng XX: Roles of deletion and regulation in creating mixed chimerism and allograft tolerance using a nonlymphoablative irradiation-free protocol. J Immunol 175: 51-60, 2005
    • (2005) J Immunol , vol.175 , pp. 51-60
    • Domenig, C.1    Sanchez-Fueyo, A.2    Kurtz, J.3    Alexopoulos, S.P.4    Mariat, C.5    Sykes, M.6    Strom, T.B.7    Zheng, X.X.8
  • 70
    • 0032852141 scopus 로고    scopus 로고
    • Combined histocompatibility leukocyte antigen matched donor bone marrow and renal transplantation for multiple myeloma with end stage renal disease: The induction of allograft tolerance through mixed lymphohematopoietic chimerism
    • Spitzer TR, Delmonico F, Tolkoff-Rubin N, McAfee S, Sackstein R, Saidman S, Colby C, Sykes M, Sachs DH, Cosimi AB: Combined histocompatibility leukocyte antigen matched donor bone marrow and renal transplantation for multiple myeloma with end stage renal disease: The induction of allograft tolerance through mixed lymphohematopoietic chimerism. Transplantation 68: 480-484, 1999
    • (1999) Transplantation , vol.68 , pp. 480-484
    • Spitzer, T.R.1    Delmonico, F.2    Tolkoff-Rubin, N.3    McAfee, S.4    Sackstein, R.5    Saidman, S.6    Colby, C.7    Sykes, M.8    Sachs, D.H.9    Cosimi, A.B.10
  • 72
    • 14344264156 scopus 로고    scopus 로고
    • Mixed hematopoietic chimerism for the simultaneous induction of T and B cell tolerance
    • Sykes M, Shimizu I, Kawahara T: Mixed hematopoietic chimerism for the simultaneous induction of T and B cell tolerance. Transplantation 79[Suppl]: S28-S29, 2005
    • (2005) Transplantation , vol.79 , Issue.SUPPL.
    • Sykes, M.1    Shimizu, I.2    Kawahara, T.3
  • 74
    • 0037617506 scopus 로고    scopus 로고
    • Infusion of donor-derived hematopoietic stem cells in organ transplantation: Clinical data
    • De Pauw L, Toungouz M, Goldman M: Infusion of donor-derived hematopoietic stem cells in organ transplantation: Clinical data. Transplantation 75[Suppl]: 46S-49S, 2003
    • (2003) Transplantation , vol.75 , Issue.SUPPL.
    • De Pauw, L.1    Toungouz, M.2    Goldman, M.3
  • 76
    • 0034088031 scopus 로고    scopus 로고
    • Immunologic 'ignorance' of vascularized organ transplants in the absence of secondary lymphoid tissue
    • Lakkis FG, Arakelov A, Konieczny BT, Inoue Y: Immunologic 'ignorance' of vascularized organ transplants in the absence of secondary lymphoid tissue. Nat Med 6: 686-688, 2000
    • (2000) Nat Med , vol.6 , pp. 686-688
    • Lakkis, F.G.1    Arakelov, A.2    Konieczny, B.T.3    Inoue, Y.4
  • 78
    • 0022354444 scopus 로고
    • Treatment of cadaveric renal transplant recipients with total lymphoid irradiation, antithymocyte globulin, and low-dose prednisone
    • Levin B, Collins G, Waer M, Girinsky T, Hoppe R, Miller E, Bieber C, Strober S: Treatment of cadaveric renal transplant recipients with total lymphoid irradiation, antithymocyte globulin, and low-dose prednisone. Lancet 326: 1321-1325, 1985
    • (1985) Lancet , vol.326 , pp. 1321-1325
    • Levin, B.1    Collins, G.2    Waer, M.3    Girinsky, T.4    Hoppe, R.5    Miller, E.6    Bieber, C.7    Strober, S.8
  • 79
    • 0034720063 scopus 로고    scopus 로고
    • Clinical transplantation tolerance twelve years after prospective withdrawal of immunosuppressive drugs: Studies of chimerism and anti-donor reactivity
    • Strober S, Benike C, Krishnaswamy S, Engleman EG, Grumet FC: Clinical transplantation tolerance twelve years after prospective withdrawal of immunosuppressive drugs: Studies of chimerism and anti-donor reactivity. Transplantation 69: 1549-1554, 2000
    • (2000) Transplantation , vol.69 , pp. 1549-1554
    • Strober, S.1    Benike, C.2    Krishnaswamy, S.3    Engleman, E.G.4    Grumet, F.C.5
  • 81
    • 0015783011 scopus 로고
    • The proportion of lymphocytes capable of recognizing strong transplantation antigens in vivo
    • Ford WL, Atkins RC: The proportion of lymphocytes capable of recognizing strong transplantation antigens in vivo. Adv Exp Med Biol 29: 255-262, 1973
    • (1973) Adv Exp Med Biol , vol.29 , pp. 255-262
    • Ford, W.L.1    Atkins, R.C.2
  • 82
    • 0035863825 scopus 로고    scopus 로고
    • Quantifying the frequency of alloreactive T cells in vivo: New answers to an old question
    • Suchin EJ, Langmuir PB, Palmer E, Sayegh MH, Wells AD, Turka LA: Quantifying the frequency of alloreactive T cells in vivo: New answers to an old question. J Immunol 166: 973-981, 2001
    • (2001) J Immunol , vol.166 , pp. 973-981
    • Suchin, E.J.1    Langmuir, P.B.2    Palmer, E.3    Sayegh, M.H.4    Wells, A.D.5    Turka, L.A.6
  • 87
    • 4544246589 scopus 로고    scopus 로고
    • Prope tolerance: The future of organ transplantation from the laboratory to the clinic
    • Calne RY: Prope tolerance: The future of organ transplantation from the laboratory to the clinic. Transpl Immunol 13: 83-86, 2004
    • (2004) Transpl Immunol , vol.13 , pp. 83-86
    • Calne, R.Y.1
  • 88
    • 33745257254 scopus 로고    scopus 로고
    • A new look at blockade of T-cell costimulation: A therapeutic strategy for long-term maintenance immunosuppression
    • Larsen CP, Knechtle SJ, Adams A, Pearson T, Kirk AD: A new look at blockade of T-cell costimulation: A therapeutic strategy for long-term maintenance immunosuppression. Am J Transplant 6: 876-883, 2006
    • (2006) Am J Transplant , vol.6 , pp. 876-883
    • Larsen, C.P.1    Knechtle, S.J.2    Adams, A.3    Pearson, T.4    Kirk, A.D.5
  • 89
    • 33845359383 scopus 로고    scopus 로고
    • Costimulatory molecules as targets for the induction of transplantation tolerance
    • Alegre ML, Najafian N: Costimulatory molecules as targets for the induction of transplantation tolerance. Curr Mol Med 8: 843-857, 2006
    • (2006) Curr Mol Med , vol.8 , pp. 843-857
    • Alegre, M.L.1    Najafian, N.2
  • 90
    • 0037080947 scopus 로고    scopus 로고
    • The CD154-CD40 costimulatory pathway in transplantation
    • Yamada A, Sayegh MH: The CD154-CD40 costimulatory pathway in transplantation. Transplantation 73[Suppl]: S36-S39, 2002
    • (2002) Transplantation , vol.73 , Issue.SUPPL.
    • Yamada, A.1    Sayegh, M.H.2
  • 91
    • 0033568118 scopus 로고    scopus 로고
    • The future of organ and tissue transplantation: Can T-cell costimulatory pathway modifiers revolutionize the prevention of graft rejection?
    • Harlan DM, Kirk AD: The future of organ and tissue transplantation: Can T-cell costimulatory pathway modifiers revolutionize the prevention of graft rejection? JAMA 282: 1076-1082, 1999
    • (1999) JAMA , vol.282 , pp. 1076-1082
    • Harlan, D.M.1    Kirk, A.D.2
  • 92
    • 0017603174 scopus 로고
    • A simple conservative explanation of the H-2 restriction of interactions between lymphocytes
    • Cunningham AJ, Lafferty KJ: A simple conservative explanation of the H-2 restriction of interactions between lymphocytes. Scand J Immunol 6: 1-6, 1977
    • (1977) Scand J Immunol , vol.6 , pp. 1-6
    • Cunningham, A.J.1    Lafferty, K.J.2
  • 100
    • 0035059417 scopus 로고    scopus 로고
    • Complexities of CD28/B7: CTLA-4 costimulatory pathways in autoimmunity and transplantation
    • Salomon B, Bluestone JA: Complexities of CD28/B7: CTLA-4 costimulatory pathways in autoimmunity and transplantation. Annu Rev Immunol 19: 225-252, 2001
    • (2001) Annu Rev Immunol , vol.19 , pp. 225-252
    • Salomon, B.1    Bluestone, J.A.2
  • 105
    • 0026629861 scopus 로고
    • Induction of donor-specific tolerance to rat cardiac allografts by intrathymic inoculation of bone marrow
    • Odorico JS: Induction of donor-specific tolerance to rat cardiac allografts by intrathymic inoculation of bone marrow. Surgery 112: 370-376, 1992
    • (1992) Surgery , vol.112 , pp. 370-376
    • Odorico, J.S.1
  • 106
    • 0028226565 scopus 로고
    • Induction of specific tolerance by intrathymic injection of recipient muscle cells transfected with donor class I major histocompatibility complex
    • Knechtle SJ, Wang J, Jiao S, Geissler EK, Sumimoto R, Wolff J: Induction of specific tolerance by intrathymic injection of recipient muscle cells transfected with donor class I major histocompatibility complex. Transplantation 57: 990-996, 1994
    • (1994) Transplantation , vol.57 , pp. 990-996
    • Knechtle, S.J.1    Wang, J.2    Jiao, S.3    Geissler, E.K.4    Sumimoto, R.5    Wolff, J.6
  • 107
    • 0027092408 scopus 로고
    • Induction of specific unresponsiveness (tolerance) to skin allografts by intrathymic donor-specific splenocyte injection in antilymphocyte serum-treated mice
    • Ohzato H, Monaco AP: Induction of specific unresponsiveness (tolerance) to skin allografts by intrathymic donor-specific splenocyte injection in antilymphocyte serum-treated mice. Transplantation 54: 1090-1095, 1992
    • (1992) Transplantation , vol.54 , pp. 1090-1095
    • Ohzato, H.1    Monaco, A.P.2
  • 108
    • 0031179509 scopus 로고    scopus 로고
    • Direct MHC class I complementary DNA transfer to thymus induces donor-specific unresponsiveness, which involves multiple immunologic mechanisms
    • Knechtle SJ, Wang J, Graeb C, Zhai Y, Hong X, Fechner JH Jr, Geissler EK: Direct MHC class I complementary DNA transfer to thymus induces donor-specific unresponsiveness, which involves multiple immunologic mechanisms. J Immunol 159: 152-158, 1997
    • (1997) J Immunol , vol.159 , pp. 152-158
    • Knechtle, S.J.1    Wang, J.2    Graeb, C.3    Zhai, Y.4    Hong, X.5    Fechner Jr, J.H.6    Geissler, E.K.7
  • 109
    • 0026787476 scopus 로고
    • Intrathymic injection of donor alloantigens induces donor-specific vascularized allograft tolerance without immunosuppression
    • Goss JA, Nakafusa Y Flye MW: Intrathymic injection of donor alloantigens induces donor-specific vascularized allograft tolerance without immunosuppression. Ann Surg 216: 414-416, 1992
    • (1992) Ann Surg , vol.216 , pp. 414-416
    • Goss, J.A.1    Nakafusa, Y.2    Flye, M.W.3
  • 110
    • 0026100948 scopus 로고
    • Kidney graft survival in rats without immunosuppressants after intrathymic glomerular transplantation
    • Remuzzi G, Rossini M, Imberti O, Perico N: Kidney graft survival in rats without immunosuppressants after intrathymic glomerular transplantation. Lancet 337: 750-752, 1991
    • (1991) Lancet , vol.337 , pp. 750-752
    • Remuzzi, G.1    Rossini, M.2    Imberti, O.3    Perico, N.4
  • 114
    • 33745174895 scopus 로고    scopus 로고
    • Tolerance assays: Measuring the unknown
    • Newell KA, Larsen CP: Tolerance assays: Measuring the unknown. Transplantation 81: 1503-1509, 2006
    • (2006) Transplantation , vol.81 , pp. 1503-1509
    • Newell, K.A.1    Larsen, C.P.2
  • 115
    • 33749263016 scopus 로고    scopus 로고
    • How can we measure immunologic tolerance in humans?
    • Najafian N, Albin MJ, Newell KA: How can we measure immunologic tolerance in humans? J Am Soc Nephrol 17: 2652-2663, 2006
    • (2006) J Am Soc Nephrol , vol.17 , pp. 2652-2663
    • Najafian, N.1    Albin, M.J.2    Newell, K.A.3
  • 116
    • 33645456450 scopus 로고    scopus 로고
    • Panel of reactive T cells as a measurement of primed cellular alloimmunity in kidney transplant candidates
    • Poggio ED, Clemente M, Hricik DE, Heeger PS: Panel of reactive T cells as a measurement of primed cellular alloimmunity in kidney transplant candidates. J Am Soc Nephrol 17: 564-572, 2006
    • (2006) J Am Soc Nephrol , vol.17 , pp. 564-572
    • Poggio, E.D.1    Clemente, M.2    Hricik, D.E.3    Heeger, P.S.4
  • 117
    • 0036138624 scopus 로고    scopus 로고
    • Enzyme-linked immunosorbent spot assay analysis of peripheral blood lymphocyte reactivity to donor HLA-DR peptides: Potential novel assay for prediction of outcomes for renal transplant recipients
    • Najafian N, Salama AD, Fedoseyeva EV, Benichou G, Sayegh MH: Enzyme-linked immunosorbent spot assay analysis of peripheral blood lymphocyte reactivity to donor HLA-DR peptides: Potential novel assay for prediction of outcomes for renal transplant recipients. J Am Soc Nephrol 13: 252-259, 2002
    • (2002) J Am Soc Nephrol , vol.13 , pp. 252-259
    • Najafian, N.1    Salama, A.D.2    Fedoseyeva, E.V.3    Benichou, G.4    Sayegh, M.H.5
  • 119
  • 120
    • 31044451821 scopus 로고    scopus 로고
    • T-lymphocyte alloresponses of Campath-1H-treated kidney transplant patients
    • Bloom DD, Hu H, Fechner JH, Knechtle SJ: T-lymphocyte alloresponses of Campath-1H-treated kidney transplant patients. Transplantation 81: 81-87, 2006
    • (2006) Transplantation , vol.81 , pp. 81-87
    • Bloom, D.D.1    Hu, H.2    Fechner, J.H.3    Knechtle, S.J.4
  • 124
    • 0032490341 scopus 로고    scopus 로고
    • Prope tolerance, perioperative Campath 1H, and low-dose cyclosporin monotherapy in renal allograft recipients
    • Calne R, Friend P, Moffatt S, Bradley A, Hale G, Firth J, Bradley J, Smith K, Waldmann H: Prope tolerance, perioperative Campath 1H, and low-dose cyclosporin monotherapy in renal allograft recipients. Lancet 351: 1701-1702, 1998
    • (1998) Lancet , vol.351 , pp. 1701-1702
    • Calne, R.1    Friend, P.2    Moffatt, S.3    Bradley, A.4    Hale, G.5    Firth, J.6    Bradley, J.7    Smith, K.8    Waldmann, H.9
  • 125
    • 0036965613 scopus 로고    scopus 로고
    • The immune tolerance network: A new paradigm for developing tolerance-inducing therapies
    • Rotrosen D, Matthews J, Bluestone J: The immune tolerance network: A new paradigm for developing tolerance-inducing therapies. J Allergy Clin Immunol 110: 17-23, 2002
    • (2002) J Allergy Clin Immunol , vol.110 , pp. 17-23
    • Rotrosen, D.1    Matthews, J.2    Bluestone, J.3
  • 126
    • 0016588625 scopus 로고
    • Discontinuance of immunosuppression in renal transplant patients
    • Owens ML: Discontinuance of immunosuppression in renal transplant patients. Arch Surg 110: 1450-1451, 1975
    • (1975) Arch Surg , vol.110 , pp. 1450-1451
    • Owens, M.L.1
  • 127
    • 0017084218 scopus 로고
    • Cessation of immunosuppression after renal transplantation
    • Uehling DT: Cessation of immunosuppression after renal transplantation. Surgery 79: 278-282, 1976
    • (1976) Surgery , vol.79 , pp. 278-282
    • Uehling, D.T.1
  • 128
    • 0029072806 scopus 로고
    • Microchimerism linked to cytotoxic T lymphocyte functional unresponsiveness (clonal anergy) in a tolerant renal transplant recipient
    • Burlingham WJ: Microchimerism linked to cytotoxic T lymphocyte functional unresponsiveness (clonal anergy) in a tolerant renal transplant recipient. Transplantation 59: 1147-1155, 1995
    • (1995) Transplantation , vol.59 , pp. 1147-1155
    • Burlingham, W.J.1
  • 129
  • 130
    • 0031777990 scopus 로고    scopus 로고
    • Indications of immunological tolerance in kidney transplantation
    • Christensen LL: Indications of immunological tolerance in kidney transplantation. Tissue Antigens 51: 637-644, 1998
    • (1998) Tissue Antigens , vol.51 , pp. 637-644
    • Christensen, L.L.1


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.