Flow-cytometric assessment of T-cell clonality in clinical specimens

Laboratory Medicine

Volumn 38, Issue 8, 2007, Pages 477-482

  Li, Ying ^a   Braylan, Raul C ^a   Al Quran, Samer Z ^a  

^a UNIVERSITY OF FLORIDA COLLEGE OF MEDICINE   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

T LYMPHOCYTE RECEPTOR;

CLINICAL LABORATORY; CLONAL VARIATION; FLOW CYTOMETRY; LYMPHOPROLIFERATIVE DISEASE; POLYMERASE CHAIN REACTION; REVIEW; T CELL LYMPHOMA; T LYMPHOCYTE;

EID: 34547641054     PISSN: 00075027     EISSN: None     Source Type: Journal    
DOI: 10.1309/FWF2FYE63AXGUWRH     Document Type: Review

References (22)

1. Ciccone E, Ferrini S, Bottino C, et al. A monoclonal antibody specific for a common determinant of the human T cell receptor gamma/delta directly activates CD3+WT31- lymphocytes to express their functional program(s). J Exp Med. 1988;168:1-11.
2. Esin S, Shigematsu M, Nagai S, et al. Different percentages of peripheral blood gamma delta + T cells in healthy individuals from different areas of the world. Scand J Immunol. 1996;43:593-596.
3. Van den Beemd R, Boor PPC, Van Lochem EG, et al. Flow cytometric analysis of the Vβ repertoire in healthy controls. Cytometry. 2000;40:336-345.
4. McCoy JP Jr, Overton WR, Schroeder K, et al. Immunophenotypic analysis of the T cell receptor V beta repertoire in CD4+ and CD8+ lymphocytes from normal peripheral blood. Cytometry. 1996;26:148-153.
5. Kazatchkine MD. Nomenclature for T-cell receptor (TCR) gene segments of the immune system: WHO-IUIS Nomenclature Sub-Committee on TCR Designation. Immunogenetics. 1995;42:451-453.
6. Rosenberg WM, Moss PA, Bell JI. Variation in human T cell receptor V beta and J beta repertoire: Analysis using anchor polymerase chain reaction. Eur J Immunol. 1992;22:541-549.
7. Lima M, Almeida J, Santos AH, et al. Immunophenotypic analysis of the TCR-Vbeta repertoire in 98 persistent expansions of CD3(+)/TCR-alphabeta(+) large granular lymphocytes: Utility in assessing clonality and insights into the pathogenesis of the disease. Am J Pathol. 2001;159:1861-1868.
8. Beck RC, Stahl S, O'Keefe CL, et al. Detection of mature T-cell leukemias by flow cytometry using anti-T-cell receptor V beta antibodies. Am J Clin Pathol. 2003;120:785-794.
9. Morice WG, Kimlinger T, Katzmann JA, et al. Flow cytometric assessment of TCR-Vbeta expression in the evaluation of peripheral blood involvement by T-cell lymphoproliferative disorders: A comparison with conventional T-cell immunophenotyping and molecular genetic techniques. Am J Clin Pathol. 2004;121:373-383.
10. Morice WG, Katzmann JA, Pittelkow MR, et al. A comparison of morphologic features, flow cytometry, TCR-Vbeta analysis, and TCR-PCR in qualitative and quantitative assessment of peripheral blood involvement by Sézary syndrome. Am J Clin Pathol. 2006;125:364-374.
11. Fitzgerald JE, Ricalton NS, Meyer AC, et al. Analysis of clonal CD8+ T cell expansions in normal individuals and patients with rheumatoid arthritis. J Immunol. 1995;154:3538-3547.
12. van den Beemd R, Boor PP, van Lochem EG, et al. Flow cytometric analysis of the Vbeta repertoire in healthy controls. Cytometry. 2000;40:336-345.
13. Lima M, Almeida J, dos Anjos Teixeira M, et al. Utility of flow cytometry immunophenotyping and DNA ploidy studies for diagnosis and characterization of blood involvement in CD4+ Sézary's syndrome. Haematologica. 2003;88:874-887.
14. Ortonne N, Huet D, Gaudez C, et al. Significance of circulating T-cell clones in Sézary syndrome. Blood. 2006;107:4030-4038. Epub. 2006 Jan 17.
15. Schwab C, Willers J, Niederer E, et al. The use of anti-T-cell receptor-Vbeta antibodies for the estimation of treatment success and phenotypic characterization of clonal T-cell populations in cutaneous T-cell lymphomas. Br J Haematol. 2002;118:1019-1026.
16. Lamberson C, Hutchison RE, Shrimpton AE. A PCR assay for detecting clonal rearrangement of the TCR-gamma gene. Mol Diagn. 2001;6:117-124.
17. Masuko-Hongo K, Kato T, Suzuki S, et al. Frequent clonal expansion of peripheral T cells in patients with autoimmune diseases: A novel detecting system possibly applicable to laboratory examination. J Clin Lab Anal. 1998;12:162-167.
18. Posnett DN, Sinha R, Kabak S, et al. Clonal populations of T cells in normal elderly humans: The T cell equivalent to "benign monoclonal gammapathy." J Exp Med. 1994;179:609-618. Erratum in: J Exp Med. 1994;179:1077. 1994; 179:609-618.
19. Timonen T, Ortaldo JR, Herberman RB. Characteristics of human large granular lymphocytes and relationship to natural killer and K cells. J Exp Med. 1981;153:569-582.
20. Dhodapkar MV, Li CY, Lust JA, et al. Clinical spectrum of clonal proliferations of T-large granular lymphocytes: A T-cell clonopathy of undetermined significance? Blood. 1994;84:1620-1627.
21. Sabnani I, Tsang P. Are clonal T-cell large granular lymphocytes to blame for unexplained haematological abnormalities? Br J Haematol. 2006;136:30-37.
22. Lima M, Almeida J, Dos Anjos Teixeira M, et al. TCRalphabeta+/CD4+ large granular lymphocytosis: A new clonal T-cell lymphoproliferative disorder. Am J Pathol. 2003;163:763-771.