The effects of tolterodine on bladder-filling sensations and perception thresholds to intravesical electrical stimulation: Method and initial results

BJU International

Volumn 100, Issue 3, 2007, Pages 574-578

  Boy, Sönke ^a   Schurch, Brigitte ^a   Mehnert, Ulrich ^a   Mehring, Gudrun ^a   Karsenty, Gilles ^a,b   Reitz, André ^a  

^a BALGRIST UNIVERSITY HOSPITAL   (Switzerland)

^b Salvator Hospital   (France)

Author keywords

Afferent pathways; Electrical stimulation; Muscarinic; Tolterodine receptors; Urinary bladder; Urothelium

Indexed keywords

TOLTERODINE;

ADULT; ARTICLE; BLADDER EMPTYING; BLADDER FILLING; CLINICAL PROTOCOL; DRUG MECHANISM; ECHOGRAPHY; ELECTRIC CURRENT; ELECTROSTIMULATION; FEMALE; HUMAN; HUMAN EXPERIMENT; MICTURITION; NORMAL HUMAN; PERCEPTIVE THRESHOLD; PRIORITY JOURNAL; REPEAT PROCEDURE; RESIDUAL URINE; SENSATION; STATISTICAL ANALYSIS; TREATMENT DURATION; URINARY URGENCY;

ADULT; BENZHYDRYL COMPOUNDS; CRESOLS; ELECTRIC STIMULATION; FEMALE; HUMANS; MUSCARINIC ANTAGONISTS; PHENYLPROPANOLAMINE; SENSATION; SENSORY THRESHOLDS; URINARY BLADDER; URODYNAMICS;

EID: 34547638941     PISSN: 14644096     EISSN: 1464410X     Source Type: Journal    
DOI: 10.1111/j.1464-410X.2007.06903.x     Document Type: Article

References (27)

1. Fetscher C, Fleichman M, Schmidt M, Krege S, Michel MC. M(3) muscarinic receptors mediate contraction of human urinary bladder. Br J Pharmacol 2002 136 : 641 3
2. Yamanishi T, Chapple CR, Chess-Williams R. Which muscarinic receptor is important in the bladder? World J Urol 2001 19 : 299 306
3. Chess-Williams R, Chapple CR, Yamanishi T, Yasuda K, Sellers DJ. The minor population of M3-receptors mediate contraction of human detrusor muscle in vitro. J Auton Pharmacol 2001 21 : 243 8
4. Andersson KE, Yoshida M. Antimuscarinics and the overactive detrusor - which is the main mechanism of action? Eur Urol 2003 43 : 1 5
5. Hawthorn MH, Chapple CR, Cock M, Chess-Williams R. Urothelium-derived inhibitory factor(s) influences on detrusor muscle contractility in vitro. Br J Pharmacol 2000 129 : 416 9
6. Di Stasi SM, Giannantoni A, Navarra P et al. Intravesical oxybutynin: mode of action assessed by passive diffusion and electromotive administration with pharmacokinetics of oxybutynin and N-desethyl oxybutynin. J Urol 2001 166 : 2232 6
7. De Wachter S, Wyndaele JJ. Intravesical oxybutynin: a local anesthetic effect on bladder C afferents. J Urol 2003 169 : 1892 5
8. Birder LA, Barrick SR, Roppolo JR et al. Feline interstitial cystitis results in mechanical hypersensitivity and altered ATP release from bladder urothelium. Am J Physiol Renal Physiol 2003 285 : F423 9
9. De Wachter S, Wyndaele JJ. Quest for standardisation of electrical sensory testing in the lower urinary tract: the influence of technique related factors on bladder electrical thresholds. Neurourol Urodyn 2003 22 : 118 22
10. Wyndaele JJ, van Eetvelde B, Callens D. Comparison in young healthy volunteers of 3 different parameters of constant current stimulation used to determine sensory thresholds in the lower urinary tract. J Urol 1996 156 : 1415 7
11. Ukimura O, Ushijima S, Honjo H et al. Neuroselective current perception threshold evaluation of bladder mucosal sensory function. Eur Urol 2004 45 : 70 6
12. Van Kerrebroeck P, Kreder K, Jonas U, Zinner N, Wein A Tolterodine Study Group. Tolterodine once-daily: superior efficacy and tolerability in the treatment of the overactive bladder. Urology 2001 57 : 414 21
13. Freeman R, Hill S, Millard R, Slack M, Sutherst J Tolterodine Study Group. Reduced perception of urgency in treatment of overactive bladder with extended-release tolterodine. Obstet Gynecol 2003 102 : 605 11
14. Abrams P, Cardozo L, Fall M et al. Standardisation Sub-committee of the International Continence Society. The standardisation of terminology of lower urinary tract function: report from the Standardisation Sub- committee of the International Continence Society. Neurourol Urodyn 2002 21 : 167 78
15. Wyndaele JJ, De Wachter S. The basics behind bladder pain: a review of data on lower urinary tract sensations. Int J Urol 2003 10 (Suppl. S49 55
16. Schmid DM, Reitz A, Curt A, Hauri D, Schurch B. Urethral evoked sympathetic skin responses and viscerosensory evoked potentials as diagnostic tools to evaluate urogenital autonomic afferent innervation in spinal cord injured patients. J Urol 2004 171 : 1156 60
17. De Wachter S, Wyndaele JJ. Does bladder tone influence sensation of filling and electro-sensation in the bladder? A blind controlled study in young healthy volunteers using bethanechol. J Urol 2001 165 : 802 4
18. Wyndaele JJ. Study on the correlation between subjective perception of bladder filling and the sensory threshold towards electrical stimulation in the lower urinary tract. J Urol 1992 147 : 1582 4
19. De Wachter S, Van Meel TD, Wyndaele JJ. Study of the afferent nervous system and its evaluation in women with impaired detrusor contractility treated with bethanechol. Urology 2003 62 : 54 8
20. De Wachter S, Wyndaele JJ. Impact of rectal distention on the results of evaluations of lower urinary tract sensation. J Urol 2003 169 : 1392 4
21. Andersson KE, Chapple C, Wein A. The basis for drug treatment of the overactive bladder. World J Urol 2001 19 : 294 8
22. Madersbacher H, Jilg G. Control of detrusor hyperreflexia by the intravesical instillation of oxybutynine hydrochloride. Paraplegia 1991 29 : 84 90
23. Greenfield SP, Fera M. The use of intravesical oxybutynin chloride in children with neurogenic bladder. J Urol 1991 146 : 532 4
24. Madersbacher H, Knoll M. Intravesical application of oxybutynine: mode of action in controlling detrusor hyperreflexia. Preliminary results. Eur Urol 1995 28 : 340 4
25. Massad CA, Kogan BA, Trigo-Rocha FE. The pharmacokinetics of intravesical and oral oxybutynin chloride. J Urol 1992 148 : 595 7
26. Kim Y, Yoshimura N, Masuda H, de Miguel F, Chancellor MB. Antimuscarinic agents exhibit local inhibitory effects on muscarinic receptors in bladder-afferent pathways. Urology 2005 65 : 238 42
27. Yokoyama O, Yusup A, Miwa Y, Oyama N, Aoki Y, Akino H. Effects of tolterodine on an overactive bladder depend on suppression of C-fiber bladder afferent activity in rats. J Urol 2005 174 : 2032 6