Comparison of various blood compartments and reporting units for the detection and quantification of Epstein-Barr virus in peripheral blood

Journal of Clinical Microbiology

Volumn 45, Issue 7, 2007, Pages 2151-2155

  Hakim, H ^a   Gibson, C ^a   Pan, J ^a   Srivastava, K ^a   Gu, Z ^a   Bankowski, M J ^b   Hayden, R T ^a  

^a ST JUDE CHILDREN S RESEARCH HOSPITAL   (United States)

^b Diagnostic Laboratory Services Inc   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

VIRUS DNA;

ARTICLE; BLOOD LEVEL; BLOOD SAMPLING; CORRELATION ANALYSIS; EPSTEIN BARR VIRUS; HUMAN; HUMAN CELL; NONHUMAN; PERIPHERAL BLOOD MONONUCLEAR CELL; PLASMA; PRIORITY JOURNAL; QUANTITATIVE ANALYSIS; QUANTITATIVE ASSAY; REAL TIME POLYMERASE CHAIN REACTION; VIRUS DETECTION; VIRUS LOAD;

DNA, VIRAL; EPSTEIN-BARR VIRUS INFECTIONS; ERYTHROCYTES; HERPESVIRUS 4, HUMAN; HUMANS; LEUKOCYTES, MONONUCLEAR; PLASMA; SENSITIVITY AND SPECIFICITY; VIRAL LOAD;

HUMAN HERPESVIRUS 4;

EID: 34547637397     PISSN: 00951137     EISSN: None     Source Type: Journal    
DOI: 10.1128/JCM.02308-06     Document Type: Article

References (32)

1. Bai, X., et al. 1997. Quantitative polymerase chain reaction for human herpesvirus diagnosis and measurement of Epstein-Barr virus burden in posttransplant lymphoproliferative disorder. Clin. Chem. 43:1843-1849.
2. Baldanti, F., et al. 2000. High levels of Epstein-Barr virus DNA in blood of solid-organ transplant recipients and their value in predicting posttransplant lymphoproliferative disorders. J. Clin. Microbiol. 38:613-619.
3. Gallagher, A., et al. 1999. Detection of Epstein-Barr virus (EBV) genomes in the serum of patients with EBV-associated Hodgkin's disease. Int. J. Cancer 84:442-448.
4. Gan, Y. J., J. L. Sullivan, and J. W. Sixbey. 1994. Detection of cell-free Epstein-Barr virus DNA in serum during acute infectious mononucleosis. J. Infect. Dis. 170:436-439.
5. Green, M., et al. 2000. Predictive negative value of persistent low Epstein-Barr virus viral load after intestinal transplantation in children. Transplantation 70:593-596.
6. Green, M., et al. 1998. Serial measurement of Epstein-Barr viral load in peripheral blood in pediatric liver transplant recipients during treatment for posttransplant lymphoproliferative disease. Transplantation 66:1641-1644.
7. Gustafsson, A., et al. 2000. Epstein-Barr virus (EBV) load in bone marrow transplant recipients at risk to develop posttransplant lymphoproliferative disease: prophylactic infusion of EBV-specific cytotoxic T cells. Blood 95:807-814.
8. Hanto, D. W., et al. 1982. Epstein-Barr virus-induced B-cell lymphoma after renal transplantation: acyclovir therapy and transition from polyclonal to monoclonal B-cell proliferation. N. Engl. J. Med. 306:913-918.
9. Jabs, W. J., et al. 2001. Normalized quantification by real-time PCR of Epstein-Barr virus load in patients at risk for posttransplant lymphoproliferative disorders. J. Clin. Microbiol. 39:564-569.
10. Kenagy, D. N., et al. 1995. Epstein-Barr virus DNA in peripheral blood leukocytes of patients with posttransplant lymphoproliferative disease. Transplantation 60:547-554.
11. Kimura, H., et al. 1999. Quantitative analysis of Epstein-Barr virus load by using a real-time PCR assay. J. Clin. Microbiol. 37:132-136.
12. Krieger, N. R., et al. 2000. Significance of detecting Epstein-Barr-specific sequences in the peripheral blood of asymptomatic pediatric liver transplant recipients. Liver Transplant. 6:62-66.
13. Limaye, A. P., et al. 1999. Detection of Epstein-Barr virus DNA in sera from transplant recipients with lymphoproliferative disorders. J. Clin. Microbiol. 37:1113-1116.
14. Lo, Y. M., et al. 1999. Quantitative analysis of cell-free Epstein-Barr virus DNA in plasma of patients with nasopharyngeal carcinoma. Cancer Res. 59:1188-1191.
15. Lo, Y. M., et al. 1999. Quantitative and temporal correlation between circulating cell-free Epstein-Barr virus DNA and tumor recurrence in nasopharyngeal carcinoma. Cancer Res. 59:5452-5455.
16. Lucas, K. G., et al. 1998. Semiquantitative Epstein-Barr virus polymerase chain reaction analysis of peripheral blood from organ transplant patients and risk for the development of lymphoproliferative disease. Blood 92:3977-3978.
17. McDiarmid, S. V., et al. 1998. Prevention and preemptive therapy of postransplant lymphoproliferative disease in pediatric liver recipients. Transplantation 66:1604-1611.
18. Niesters, H. G., et al. 2000. Development of a real-time quantitative assay for detection of Epstein-Barr virus. J. Clin. Microbiol. 38:712-715.
19. Riddler, S. A., M. C. Breinig, and J. L. Mcknight. 1994. Increased levels of circulating Epstein-Barr virus (EBV)-infected lymphocytes and decreased EBV nuclear antigen antibody responses are associated with the development of posttransplant lymphoproliferative disease in solid-organ transplant recipients. Blood 84:972-984.
20. Rooney, C. M., et al. 1995. Early identification of Epstein-Barr virus-associated post-transplantation lymphoproliferative disease. Br. J. Haematol. 89:98-103.
21. Rowe, D. T., et al. 1997. Use of quantitative competitive PCR to measure Epstein-Barr virus genome load in the peripheral blood of pediatric transplant patients with lymphoproliferative disorders. J. Clin. Microbiol. 35:1612-1615.
22. Savoie, A., et al. 1994. Direct correlation between the load of Epstein-Barr virus-infected lymphocytes in the peripheral blood of pediatric transplant patients and risk of lymphoproliferative disease. Blood 83:2715-2722.
23. Stevens, S. J., et al. 1999. Monitoring of Epstein-Barr virus DNA load in peripheral blood by quantitative competitive PCR. J. Clin. Microbiol. 37:2852-2857.
24. Stevens, S. J., et al. 2002. Comparison of quantitative competitive PCR with LightCycler-based PCR for measuring Epstein-Barr virus DNA load in clinical specimens. J. Clin. Microbiol. 40:3986-3992.
25. Stevens, S. J., I. Pronk, and J. M. Middeldorp. 2001. Toward standardization of Epstein-Barr virus DNA load monitoring: unfractionated whole blood as preferred clinical specimen. J. Clin. Microbiol. 39:1211-1216.
26. Reference deleted.
27. Wadowsky, R. M., et al. 2003. Measurement of Epstein-Barr virus DNA loads in whole blood and plasma by TaqMan PCR and in peripheral blood lymphocytes by competitive PCR. J. Clin. Microbiol. 41:5245-5249.
28. Wagner, H. J., et al. 1992. Detection and quantification of latently infected B lymphocytes in Epstein-Barr virus-seropositive, healthy individuals by polymerase chain reaction. J. Clin. Microbiol. 30:2826-2829.
29. Wagner, H. J., et al. 2000. Real-time polymerase chain reaction (RQ-PCR) for the monitoring of Epstein-Barr virus (EBV) load in peripheral blood mononuclear cells. Klin. Padiatr. 212:206-210.
30. Wagner, H. J., et al. 2002. Longitudinal analysis of Epstein-Barr viral load in plasma and peripheral blood mononuclear cells of transplanted patients by real-time polymerase chain reaction. Transplantation 74:656-664.
31. Wagner, H. J., et al. 2001. Patients at risk for development of posttransplant lymphoproliferative disorder: plasma versus peripheral blood mononuclear cells as material for quantification of Epstein-Barr viral load by using real-time quantitative polymerase chain reaction. Transplantation 72:1012-1019.
32. Yamamoto, M., et al. 1995. Detection and quantification of virus DNA in plasma of patients with Epstein-Barr virus-associated diseases. J. Clin. Microbiol. 33:1765-1768.