Biological characterization of rodent and human vasopressin V 1b receptors using SSR-149415, a nonpeptide V 1b receptor ligand

American Journal of Physiology - Regulatory Integrative and Comparative Physiology

Volumn 293, Issue 2, 2007, Pages

  Serradeil Le Gal, Claudine ^a   Raufaste, Danièle ^a   Derick, Sylvain ^a   Blankenstein, Jörg ^a   Allen, John ^a   Pouzet, Brigitte ^a   Pascal, Marc ^a   Wagnon, Jean ^a   Ventura, Maria Angeles ^b,c  

^a SANOFI   (France)

^b CNRS   (France)

^c INSERM   (France)

Author keywords

Hamster; Human; Mouse; Rat; V 1b receptor; Vasopressin

Indexed keywords

1 [5 CHLORO 1 (2,4 DIMETHOXYLPHENYLSULFONYL) 2,3 DIHYDRO 3 (2 METHOXYPHENYL) 2 OXO 1H INDOL 3 YL] 4 HYDROXY N,N DIMETHYL 2 PYRROLIDINECARBOXAMIDE; ARGIPRESSIN; INOSITOL PHOSPHATE; PEPTIDE HORMONE ANTAGONIST; RADIOLIGAND; RELCOVAPTAN; SR 121463B; SSR 126768A; UNCLASSIFIED DRUG; VASOPRESSIN V1B RECEPTOR;

ANALYTIC METHOD; ANIMAL CELL; ARTICLE; AUTORADIOGRAPHY; BINDING AFFINITY; BINDING SITE; COMPARATIVE STUDY; CONTROLLED STUDY; DISSOCIATION CONSTANT; FEMALE; HUMAN; HUMAN TISSUE; NONHUMAN; ORDO; PRIORITY JOURNAL; PROTEIN ANALYSIS; PROTEIN BINDING; SCATCHARD PLOT;

ANIMALS; AUTORADIOGRAPHY; CALCIUM; CELL LINE; CRICETINAE; DNA, COMPLEMENTARY; ENDOCYTOSIS; HUMANS; INDOLES; INOSITOL PHOSPHATES; LIGANDS; MEMBRANE PROTEINS; MICE; PYRROLIDINES; RADIOLIGAND ASSAY; RECEPTORS, VASOPRESSIN; RECOMBINANT PROTEINS; SENSITIVITY AND SPECIFICITY; TRITIUM;

EID: 34547632887     PISSN: 03636119     EISSN: 15221490     Source Type: Journal    
DOI: 10.1152/ajpregu.00062.2007     Document Type: Article

References (32)

1. Aguilera G, Rabadan-Diehl C. Vasopressinergic regulation of the hypothalamic-pituitary-adrenal axis: implications for stress adaptation. Regul Pept 96: 23-29, 2000.
2. Barberis C, Morin D, Durroux T, Mouillac B, Guillon G, Seyer R, Hibert M, Tribollet E, Manning M. Molecular pharmacology of AVP and OT receptors and therapeutic potential. Drug News Perspect 12: 279-292, 1999.
3. Bernard K, Bogliolo S, Ehrenfeld. Vasotocin and vasopressin stimulation of the chloride secretion in the human bronchial epithelial cell line, 16HBE14o-. J Br J Pharmacol 144: 1037-502, 2005.
4. Bouley R, Lin HY, Raychowdhury MK, Marshansky V, Brown D, Ausiello DA. Downregulation of the vasopressin type 2 receptor after vasopressin-induced internalization: involvement of a lysosomal degradation pathway. Am J Physiol Cell Physiol 288: C1390-C1401, 2005.
5. Bradford MM. A rapid, and sensitive method for quantitation of microgram quantities of protein utilizes the principle of protein-dye binding. Anal Biochem 72: 248-254, 1976.
6. Burbach JPH, Adan RA, Lolait SJ, van Leeuwen FW, Mezey E, Palkovits M, Barberis C. Molecular neurobiology and pharmacology of the vasopressin/oxytocin receptor family. Cell Mol Neurobiol 15: 573-595, 1995.
7. 50) of an enzymatic reaction. Biochem Pharmacol 22: 3099-3108, 1973.
8. De Keyzer Y, Auzan F, Beldford C, Thibonnier M, Bertagna X, Clauser E. Cloning and characterization of the human V3 pituitary vasopressin receptor. FEBS Lett 356: 215-220, 1994.
9. 3) and corticotrophin-releasing hormone receptor genes in corticotroph tumours. Clin Endocrinol 49: 475-482, 1998.
10. Derick S, Cheng LL, Voirol MJ, Stoev S, Giacomini M, Wo NC, Szeto HH, Ben Mimoun M, Andrès M, Gaillard RC, Guillon G, Manning M. [1-Deamino-4-cyclohexylalanine]arginine vasopressin: a potent and specific agonist for vasopressin V1b receptors. Endocrinology 143: 4655-4664, 2002.
11. Dickstein G, DeBold CR, Gaitan D, DeCherney GS, Jackson RV, Sheldon WR Jr, Nicholson WE, Orth DN. Plasma corticotropin and cortisol responses to ovine corticotropin-releasing hormone (CRH), arginine vasopressin (AVP), CRH plus AVP, and CRH plus metyrapone in patients with Cushing's disease. J Clin Endocrinol Metab 81: 2934-2941, 1996.
12. Folny V, Raufaste D, Lukovic L, Pouzet B, Rochard P, Pascal M, Serradeil-Le Gal C. Pancreatic vasopressin V1b receptors: characterization in In-R1-G9 cells and localization in human pancreas. Am J Physiol Endocrinol Metab 285: E566-E576, 2003.
13. Gaillard RC, Schoenenberg P, Favrod-Coune CA, Muller AF, Marie J, Bockaert J, Jard S. Properties of rat anterior pituitary vasopressin receptors: relation to adenylate cyclase and the effect of corticotropin- releasing factor. Proc Natl Acad Sci USA 81: 2907-2911, 1984.
14. Gillies GE, Linton EA, Lowry PJ. Corticotropin releasing activity of the new CRF is potentiated several times by vasopressin. Nature 299: 355-357, 1982.
15. Grazzini E, Breton C, Derick S, Andres M, Raufaste D, Rickwaert F, Boccara G, Colson P, Guerineau NC, Serradeil-Le Gal C, Guillon G. Vasopressin receptors in human adrenal medulla and pheochromocytoma. J Clin Endocrinol Metab 84: 2195-2203, 1999.
16. Griebel G, Simiand J, Serradeil-Le Gal C, Wagnon J, Pascal M, Scatton B, Maffrand JP, Soubrié P. Anxiolytic- and antidepressant-like effects of the non-peptide vasopressin V1b receptor antagonist, SSR149415, suggest an innovative approach for the treatment of stress-related disorders. Proc Natl Acad Sci USA 99: 6370-6375, 2002.
17. Griffante C, Green A, Curcuruto O, Haslam CP, Dickinson BA, Arban R. Selectivity of d[Cha4]AVP and SSR149415 at human vasopressin and oxytocin receptors: evidence that SSR149415 is a mixed vasopressin V1b/oxytocin receptor antagonist. Br J Pharmacol 146: 744-751, 2005.
18. Guillon G, Derick S, Pena A, Cheng LL, Stoev S, Seyer R, Morgat JL, Barberus C, Serradeil-Le Gal C, Wagnon J, Manning M. The discovery of novel vasopressin V1b receptor ligands for pharmacological, functional and structural investigations. J Neuroendocrinol 16: 356-361, 2004.
19. Janecka A, Poels J, Fichna J, Studzian K, Vanden Broeck J. Comparison of antagonist activity of spantide family at human neurokinin receptors measured by aequorin luminescence-based functional calcium assay. Regul Pept 131: 23-28, 2005.
20. Jard S. Vasopressin receptors. A historical survey. Adv Exp Med Biol 449: 1-13, 1998.
21. Klein U, Fahrenholz F. Reconstitution of the myometrial oxytocin receptor into proteoliposomes. Dependence of oxytocin binding on cholesterol. Eur J Biochem 220: 559-567, 1994.
22. Lolait SJ, O'Carroll AM, Brownstein MJ. Molecular biology of vasopressin receptors. Ann NY Acad Sci 771: 273-292, 1995a.
23. Lolait SJ, O'Carroll AM, Mahan LC, Felder CC, Button DC, Young WS, III, Mezey E, Brownstein MJ. Extrapituitary expression of the rat V1b vasopressin receptor gene. Proc Natl Acad Sci USA 92: 6783-6787, 1995.
24. Milou B, Lupker J. Rapid isolation of highly productive recombinant Chinese hamster ovary cell lines. Gene 149: 341-344, 1994.
25. Morello JP, Salahpour A, Laperriere A, Bernier V, Arthus MF, Lonergan M, Petäjä-Repo U, Angers S, Morin D, Bichet DG, Bouvier M. Pharmacological chaperones rescue cell-surface expression and function of misfolded V2 vasopressin receptor mutants. J Clin Invest 105: 887-895, 2000.
26. North WG, Fay MJ, Longo KA, Du J. Expression of all known vasopressin receptor subtypes by small cell tumors implies a multifaceted role for this neuropeptide. Cancer Res 58: 1866-1871, 1998.
27. Oakley RH, Laporte SA, Holt JA, Barak LS, Caron MG. Association of beta-arrestin with G protein-coupled receptors during clathrin-mediated endocytosis dictates the profile of receptor resensitization. J Biol Chem 274: 32248-32257, 1999.
28. Oshikawa S, Tanoue A, Koshimizu TA, Kitagawa Y, Tsujimoto G. Vasopressin stimulates insulin release from islet cells through V1b receptors: a combined pharmacological/knockout approach. Mol Pharmacol 65: 623-6299, 2004.
29. Pettibone DJ, Kishel MT, Woyden CJ, Clineschmidt BV, Bock MG, Freidinger RM, Veber DF, Williams PD. Radioligand binding studies reveal marked species differences in the vasopressin V1 receptor of rat, rhesus and human tissues. Life Sci 50: 1953-1958, 1992.
30. Rivier C, Vale W. Interaction of corticotropin-releasing factor and arginine vasopressin on adrenocorticotropin secretion in vivo. Endocrinology 113: 939-942, 1983.
31. Robert J, Auzan C, Ventura MA, Clauser E. Mechanisms of cellsurface rerouting of an endoplasmic reticulum-retained mutant of the vasopressin V1b/V3 receptor by a pharmacological chaperone. J Biol Chem 280: 42198-43206, 2005.
32. 1b vasopressin receptor: evidence for its expression in extra-pituitary tissues. Biochem Biophys Res Commun 212: 751-757, 1995.