메뉴 건너뛰기




Volumn 45, Issue 8, 2007, Pages 551-562

The treatment of spasticity with Δ9-tetrahydrocannabinol in persons with spinal cord injury

Author keywords

Cannabinoid; Cannabis; Pain; Spasticity; Spinal cord injury; THC

Indexed keywords

DRONABINOL; PLACEBO; TETRAHYDROCANNABINOL DERIVATIVE; TETRAHYDROCANNABINOL HEMISUCCINATE; UNCLASSIFIED DRUG; TETRAHYDROCANNABINOL;

EID: 34547623372     PISSN: 13624393     EISSN: 14765624     Source Type: Journal    
DOI: 10.1038/sj.sc.3101982     Document Type: Article
Times cited : (65)

References (51)
  • 1
    • 0001978419 scopus 로고    scopus 로고
    • The pharmacohistory of Cannabis sativa
    • Mechoulam R ed, CRC Press: Boca Raton
    • Mechoulam R. The pharmacohistory of Cannabis sativa. In: Mechoulam R (ed). Cannabinoids as Therapeutic Agents. CRC Press: Boca Raton.
    • Cannabinoids as Therapeutic Agents
    • Mechoulam, R.1
  • 2
    • 50549108561 scopus 로고
    • Therapeutic uses and toxic effects of Cannabis indica
    • Reynolds JR. Therapeutic uses and toxic effects of Cannabis indica. Lancet 1890; 1: 637-638.
    • (1890) Lancet , vol.1 , pp. 637-638
    • Reynolds, J.R.1
  • 3
    • 0016353831 scopus 로고
    • The perceived effects of marijuana on spinal cord injured males
    • Dunn M, Davis R. The perceived effects of marijuana on spinal cord injured males. Paraplegia 1974; 12: 175.
    • (1974) Paraplegia , vol.12 , pp. 175
    • Dunn, M.1    Davis, R.2
  • 4
    • 0020084379 scopus 로고
    • Cannabis effect on spasticity in spinal cord injury
    • Malec J, Harvey RF, Cayner JJ. Cannabis effect on spasticity in spinal cord injury. Arch Phys Med Rehabil 1982; 63: 116-118.
    • (1982) Arch Phys Med Rehabil , vol.63 , pp. 116-118
    • Malec, J.1    Harvey, R.F.2    Cayner, J.J.3
  • 5
    • 0030740514 scopus 로고    scopus 로고
    • The perceived effects of smoked cannabis on patients with multiple sclerosis
    • Consroe P, Musty R, Rein J, Tillery W, Pertwee R. The perceived effects of smoked cannabis on patients with multiple sclerosis. Eur Neurol 1997; 38: 44-48.
    • (1997) Eur Neurol , vol.38 , pp. 44-48
    • Consroe, P.1    Musty, R.2    Rein, J.3    Tillery, W.4    Pertwee, R.5
  • 6
    • 0038501467 scopus 로고    scopus 로고
    • Reported marijuana effects in patients with spinal cord injury
    • International Cannabinoid Research Society: Burlington
    • Consroe P, Tillery W, Rein J, Musty RE. Reported marijuana effects in patients with spinal cord injury. 1998 Symposium on the Cannabinoids. International Cannabinoid Research Society: Burlington 1998, p 64.
    • (1998) 1998 Symposium on the Cannabinoids , pp. 64
    • Consroe, P.1    Tillery, W.2    Rein, J.3    Musty, R.E.4
  • 7
    • 0018866632 scopus 로고
    • Marijuna as a therapeutic agent for muscle spasm or spasticity
    • Petro DJ. Marijuna as a therapeutic agent for muscle spasm or spasticity. Psychosomatics 1980; 21: 81-85.
    • (1980) Psychosomatics , vol.21 , pp. 81-85
    • Petro, D.J.1
  • 8
    • 0024478281 scopus 로고
    • Effect of cannabinoids on spasticity and ataxia in multiple sclerosis
    • Meinck HM, Conrad B. Effect of cannabinoids on spasticity and ataxia in multiple sclerosis. J Neurol 1989; 236: 120-122.
    • (1989) J Neurol , vol.236 , pp. 120-122
    • Meinck, H.M.1    Conrad, B.2
  • 11
    • 0025109126 scopus 로고
    • Delta-9-tetrahydrocannabinol shows anti-spastic and analgesic effects in a single case double-blind trial
    • Maurer M, Henn V, Dittrich A, Hofmann A. Delta-9-tetrahydrocannabinol shows anti-spastic and analgesic effects in a single case double-blind trial. Eur Arch Psychiat Clin Neurosci 1990; 240: 1-4.
    • (1990) Eur Arch Psychiat Clin Neurosci , vol.240 , pp. 1-4
    • Maurer, M.1    Henn, V.2    Dittrich, A.3    Hofmann, A.4
  • 12
    • 0028950529 scopus 로고
    • Nabilone in the treatment of multiple sclerosis
    • Martyn CN, Illis LS, Thom J. Nabilone in the treatment of multiple sclerosis. Lancet 1995; 345: 579.
    • (1995) Lancet , vol.345 , pp. 579
    • Martyn, C.N.1    Illis, L.S.2    Thom, J.3
  • 13
    • 0029797827 scopus 로고    scopus 로고
    • The effect of orally and rectally administered delta-9-tetrahydrocannabinol on spasticity: A pilot study with 2 patients
    • Brenneisen R, Egli A, Elsohly MA, Henn V, Spiess Y. The effect of orally and rectally administered delta-9-tetrahydrocannabinol on spasticity: a pilot study with 2 patients. Int J Clin Pharmacol Ther 1996; 34: 446-452.
    • (1996) Int J Clin Pharmacol Ther , vol.34 , pp. 446-452
    • Brenneisen, R.1    Egli, A.2    Elsohly, M.A.3    Henn, V.4    Spiess, Y.5
  • 14
    • 0037255987 scopus 로고    scopus 로고
    • Pharmacokinetics and pharmacodynamics of cannabinoids
    • Grotenhermen F. Pharmacokinetics and pharmacodynamics of cannabinoids. Clin Pharmacokin 2003; 42: 327-360.
    • (2003) Clin Pharmacokin , vol.42 , pp. 327-360
    • Grotenhermen, F.1
  • 16
    • 0033538482 scopus 로고    scopus 로고
    • Motor actions of cannabinoids in the basal ganglia output nuclei
    • Sañudo-Peña MC, Tsou K, Walker JM. Motor actions of cannabinoids in the basal ganglia output nuclei. Life Sci 1999; 65: 703-713.
    • (1999) Life Sci , vol.65 , pp. 703-713
    • Sañudo-Peña, M.C.1    Tsou, K.2    Walker, J.M.3
  • 17
    • 84921430368 scopus 로고    scopus 로고
    • Pharmacological interventions for spasticity following spinal cord injury (Cochrane Review)
    • CD001131
    • Tarrico M, Adone R, Pagliacci C, Telaro E. Pharmacological interventions for spasticity following spinal cord injury (Cochrane Review). Cochrane Database Syst Rev 2000; 2: CD001131.
    • (2000) Cochrane Database Syst Rev , vol.2
    • Tarrico, M.1    Adone, R.2    Pagliacci, C.3    Telaro, E.4
  • 19
    • 0242654882 scopus 로고    scopus 로고
    • Cannabinoids for treatment of spasticity and other symptoms related to multiple sclerosis (CAMS study): Multicentre randomised placebo-controlled trial
    • Zajicek J et al. Cannabinoids for treatment of spasticity and other symptoms related to multiple sclerosis (CAMS study): multicentre randomised placebo-controlled trial. Lancet 2003; 362: 1517-1526.
    • (2003) Lancet , vol.362 , pp. 1517-1526
    • Zajicek, J.1
  • 20
    • 18944375477 scopus 로고    scopus 로고
    • The cannabinoids in MS study - final results from 12 months follow-up
    • Zajicek J. The cannabinoids in MS study - final results from 12 months follow-up. Mult Scler 2004; 10(Suppl 2): 115.
    • (2004) Mult Scler , vol.10 , Issue.SUPPL. 2 , pp. 115
    • Zajicek, J.1
  • 21
    • 4344571664 scopus 로고    scopus 로고
    • Efficacy, safety and tolerability of an orally administered cannabis extract in the treatment of spasticity in patients with multiple sclerosis: A randomized, double-blind, placebo-controlled, crossover study
    • Vaney C et al. Efficacy, safety and tolerability of an orally administered cannabis extract in the treatment of spasticity in patients with multiple sclerosis: a randomized, double-blind, placebo-controlled, crossover study. Mult Scler 2004; 10: 417-424.
    • (2004) Mult Scler , vol.10 , pp. 417-424
    • Vaney, C.1
  • 22
    • 4344582253 scopus 로고    scopus 로고
    • Do cannabis-based medicinal extracts have general or specific effects on symptoms in multiple sclerosis? A double-blind, randomized, placebo-controlled study on 160 patients
    • Wade DT, Makela P, Robson P, House H, Bateman C. Do cannabis-based medicinal extracts have general or specific effects on symptoms in multiple sclerosis? A double-blind, randomized, placebo-controlled study on 160 patients. Mult Scler 2004; 10: 434-441.
    • (2004) Mult Scler , vol.10 , pp. 434-441
    • Wade, D.T.1    Makela, P.2    Robson, P.3    House, H.4    Bateman, C.5
  • 23
    • 0023130157 scopus 로고
    • Interrater reliability of a modified Ashworth scale of muscle spasticity
    • Bohannon RW, Smith MB. Interrater reliability of a modified Ashworth scale of muscle spasticity. Phys Ther 1987; 67: 206-207.
    • (1987) Phys Ther , vol.67 , pp. 206-207
    • Bohannon, R.W.1    Smith, M.B.2
  • 26
    • 0029157842 scopus 로고
    • Continious performance tests: A comparison of modalities
    • Baker DB, Taylor CJ, Leyva C. Continious performance tests: a comparison of modalities. J Clin Psychol 1995; 51(4): 548-551.
    • (1995) J Clin Psychol , vol.51 , Issue.4 , pp. 548-551
    • Baker, D.B.1    Taylor, C.J.2    Leyva, C.3
  • 28
    • 0037076468 scopus 로고    scopus 로고
    • Safety, tolerability, and efficacy of orally administered cannabinoids in MS
    • Killestein J et al. Safety, tolerability, and efficacy of orally administered cannabinoids in MS. Neurology 2002; 58: 1404-1407.
    • (2002) Neurology , vol.58 , pp. 1404-1407
    • Killestein, J.1
  • 29
    • 0032926740 scopus 로고    scopus 로고
    • Prescribing cannabinoids for multiple sclerosis
    • Pertwee RG. Prescribing cannabinoids for multiple sclerosis. CNS Drugs 1999; 11: 327-334.
    • (1999) CNS Drugs , vol.11 , pp. 327-334
    • Pertwee, R.G.1
  • 30
    • 0020536571 scopus 로고
    • Tetrahydrocannabinol for tremor in multiple sclerosis
    • Clifford DB. Tetrahydrocannabinol for tremor in multiple sclerosis. Ann Neurol 1983; 13: 669-671.
    • (1983) Ann Neurol , vol.13 , pp. 669-671
    • Clifford, D.B.1
  • 31
    • 0347186057 scopus 로고    scopus 로고
    • Maximally tolerated dose (mtd) of standardized cannabis extract in palliative cancer patients: Preliminary results from an open label, on-randomized phase I/II trial
    • International Association Cannabis as Medicine, Cologne, September 12-13
    • Helwig S, Fronk EM, Reif M, Schnelle M, Hoffmann J. Maximally tolerated dose (mtd) of standardized cannabis extract in palliative cancer patients: preliminary results from an open label, on-randomized phase I/II trial. Second Conference on Cannabis and Cannabinoids International Association Cannabis as Medicine, Cologne, September 12-13, 2003.
    • (2003) Second Conference on Cannabis and Cannabinoids
    • Helwig, S.1    Fronk, E.M.2    Reif, M.3    Schnelle, M.4    Hoffmann, J.5
  • 32
    • 0141716282 scopus 로고
    • Treatment of spasticity in spinal cord injury with dronabinol, a tetrahydrocannabinol derivate
    • Kogel RW, Johnson PB, Chintam R, Robinson CHJ, Nemchausky BA. Treatment of spasticity in spinal cord injury with dronabinol, a tetrahydrocannabinol derivate. Am J Ther 1995; 2: 799-805.
    • (1995) Am J Ther , vol.2 , pp. 799-805
    • Kogel, R.W.1    Johnson, P.B.2    Chintam, R.3    Robinson, C.H.J.4    Nemchausky, B.A.5
  • 33
    • 4243775504 scopus 로고    scopus 로고
    • Developing a patient-based measure of the impact of spasticity in multiple sclerosis
    • Riazi A, Fox P, Vickery J, Thompson AJ, Zajicek J, Hobart JC. Developing a patient-based measure of the impact of spasticity in multiple sclerosis. Mult Scler 2003; 9: 151.
    • (2003) Mult Scler , vol.9 , pp. 151
    • Riazi, A.1    Fox, P.2    Vickery, J.3    Thompson, A.J.4    Zajicek, J.5    Hobart, J.C.6
  • 34
    • 0025854182 scopus 로고
    • Trends in the pathophysiology and pharmacotherapy of spasticity
    • Noth J. Trends in the pathophysiology and pharmacotherapy of spasticity. J Neurol 1991; 238: 131-139.
    • (1991) J Neurol , vol.238 , pp. 131-139
    • Noth, J.1
  • 37
    • 0035256557 scopus 로고    scopus 로고
    • Endocannabinoids control spasticity in a multiple sclerosis model
    • Baker D et al. Endocannabinoids control spasticity in a multiple sclerosis model. FASEB J 2001; 15: 300-302.
    • (2001) FASEB J , vol.15 , pp. 300-302
    • Baker, D.1
  • 38
    • 0345669751 scopus 로고    scopus 로고
    • A preliminary controlled study to determine whether whole-plant cannabis extracts can improve intractable neurogenic symptoms
    • Wade DT, Robson P, House H, Makela P, Aram J. A preliminary controlled study to determine whether whole-plant cannabis extracts can improve intractable neurogenic symptoms. Clin Rehabil 2003; 17: 18-26.
    • (2003) Clin Rehabil , vol.17 , pp. 18-26
    • Wade, D.T.1    Robson, P.2    House, H.3    Makela, P.4    Aram, J.5
  • 39
    • 4344585483 scopus 로고    scopus 로고
    • An open label pilot study of cannabis-based extracts for bladder dysfunction in advanced muliple sclerosis
    • Brady CM, DasGupta R, Dalton C, Wiseman OJ, Berkely KJ, Fowler CJ. An open label pilot study of cannabis-based extracts for bladder dysfunction in advanced muliple sclerosis. Mult Scler 2004; 10: 425-433.
    • (2004) Mult Scler , vol.10 , pp. 425-433
    • Brady, C.M.1    DasGupta, R.2    Dalton, C.3    Wiseman, O.J.4    Berkely, K.J.5    Fowler, C.J.6
  • 40
    • 0035144653 scopus 로고    scopus 로고
    • Influence of treatment of Tourette syndrome with delta9-tetrahydrocannabinol (delta9-THC) on neuropsychological performance
    • Müller-Vahl KR, Koblenz A, Jobges M, Kolbe H, Emrich HM, Schneider U. Influence of treatment of Tourette syndrome with delta9-tetrahydrocannabinol (delta9-THC) on neuropsychological performance. Pharmacopsychiatry 2001; 34: 19-24.
    • (2001) Pharmacopsychiatry , vol.34 , pp. 19-24
    • Müller-Vahl, K.R.1    Koblenz, A.2    Jobges, M.3    Kolbe, H.4    Emrich, H.M.5    Schneider, U.6
  • 41
    • 4043096916 scopus 로고    scopus 로고
    • Does the cannabinoid dronabinol reduce central pain in multiple sclerosis? Randomised double blind placebo controlled crossover trial
    • Svendsen KB, Jensen TS, Bach FW. Does the cannabinoid dronabinol reduce central pain in multiple sclerosis? Randomised double blind placebo controlled crossover trial. BMJ 2004; 329: 253-260.
    • (2004) BMJ , vol.329 , pp. 253-260
    • Svendsen, K.B.1    Jensen, T.S.2    Bach, F.W.3
  • 42
    • 34547642210 scopus 로고    scopus 로고
    • Randomised controlled trial of cannabis based medicinal extracts (CBME) in central neuropathic pain due to multiple sclerosis
    • September 2-6, Prag
    • Young CA, Rog DJ. Randomised controlled trial of cannabis based medicinal extracts (CBME) in central neuropathic pain due to multiple sclerosis. IV. Congress of the European Federation of IASP Chapters (EFIC) September 2-6, 2003, Prag.
    • (2003) IV. Congress of the European Federation of IASP Chapters (EFIC)
    • Young, C.A.1    Rog, D.J.2
  • 43
    • 9244223576 scopus 로고    scopus 로고
    • Efficacy of two cannabis based medicinal extracts for relief of central neuropathic pain from brachial plexus avulsion: Results of a randomised controlled trial
    • Berman JS, Symonds C, Birch R. Efficacy of two cannabis based medicinal extracts for relief of central neuropathic pain from brachial plexus avulsion: results of a randomised controlled trial. Pain 2004; 112: 299-306.
    • (2004) Pain , vol.112 , pp. 299-306
    • Berman, J.S.1    Symonds, C.2    Birch, R.3
  • 44
    • 84862372804 scopus 로고    scopus 로고
    • The effects of smoked cannabis in painful peripheral neuropathy and cancer pain refractory to opioids
    • Cologne, September 12-13
    • Abrams DI et al. The effects of smoked cannabis in painful peripheral neuropathy and cancer pain refractory to opioids. IACM 2nd Conference on Cannabinoids in Medicine Cologne, September 12-13, 2003.
    • (2003) IACM 2nd Conference on Cannabinoids in Medicine
    • Abrams, D.I.1
  • 46
    • 0019605653 scopus 로고
    • Effects of moderate and high doses of marihuana on thermal pain: A sensory decision theory analysis
    • 8-9 Suppl, 299-310
    • Clark WC, Janal MN, Zeidenberg P, Nahas GG. Effects of moderate and high doses of marihuana on thermal pain: a sensory decision theory analysis. J Clin Pharmacol 1981; 21(8-9 Suppl): 299-310.
    • (1981) J Clin Pharmacol , vol.21
    • Clark, W.C.1    Janal, M.N.2    Zeidenberg, P.3    Nahas, G.G.4
  • 48
    • 0141515748 scopus 로고    scopus 로고
    • The analgesic effect of oral delta-9-tetrahydrocannabinol (THC), morphine, and a THC-morphine combination in healthy subjects under experimental pain conditions
    • Naef M, Curatolo M, Petersen-Felix S, Arendt-Nielsen L, Zbinden A, Brenneisen R. The analgesic effect of oral delta-9-tetrahydrocannabinol (THC), morphine, and a THC-morphine combination in healthy subjects under experimental pain conditions. Pain 2003; 105: 79-88.
    • (2003) Pain , vol.105 , pp. 79-88
    • Naef, M.1    Curatolo, M.2    Petersen-Felix, S.3    Arendt-Nielsen, L.4    Zbinden, A.5    Brenneisen, R.6
  • 49
    • 0017349888 scopus 로고
    • Effects of intravenous tetrahydrocannabinol on experimental and surgical pain. Psychological correlates of the analgesic response
    • Raft D, Gregg J, Ghia J, Harris L. Effects of intravenous tetrahydrocannabinol on experimental and surgical pain. Psychological correlates of the analgesic response. Clin Pharmacol Ther 1977; 21: 26-33.
    • (1977) Clin Pharmacol Ther , vol.21 , pp. 26-33
    • Raft, D.1    Gregg, J.2    Ghia, J.3    Harris, L.4
  • 51
    • 0018082126 scopus 로고
    • The effects of smoked marijuana on metabolism and respiratory control
    • Zwillich CW, Doekel R, Hammill S, Weil JV. The effects of smoked marijuana on metabolism and respiratory control. Am Rev Respir Dis 1978; 118: 885-891.
    • (1978) Am Rev Respir Dis , vol.118 , pp. 885-891
    • Zwillich, C.W.1    Doekel, R.2    Hammill, S.3    Weil, J.V.4


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.