A del T poly T (8) mutation in the 3′ untranslated region (UTR) of the CDK2-AP1 gene is functionally significant causing decreased mRNA stability resulting in decreased CDK2-AP1 expression in human microsatellite unstable (MSI) colorectal cancer (CRC)

Surgery

Volumn 142, Issue 2, 2007, Pages 222-227

  Shin, Joongho ^a   Yuan, Ziqian ^a   Fordyce, Kenneth ^a   Sreeramoju, Prashanth ^a   Kent, Tara S ^a   Kim, John ^a   Wang, Victor ^a   Schneyer, David ^a   Weber, Thomas K ^a  

^a ALBERT EINSTEIN COLLEGE OF MEDICINE   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

CYCLIN DEPENDENT KINASE 2; CYCLIN DEPENDENT KINASE 2 ASSOCIATED PROTEIN 1; DACTINOMYCIN; GREEN FLUORESCENT PROTEIN; MESSENGER RNA; POLYTHYMIDYLIC ACID; UNCLASSIFIED DRUG;

3' UNTRANSLATED REGION; ARTICLE; CANCER CELL CULTURE; COMPUTER PROGRAM; CONTROLLED STUDY; EMBRYO; FLUORESCENCE ACTIVATED CELL SORTING; GENE DELETION; GENE EXPRESSION; GENETIC TRANSCRIPTION; HUMAN; HUMAN CELL; MICROSATELLITE INSTABILITY; MUTANT; PRIORITY JOURNAL; REAL TIME POLYMERASE CHAIN REACTION; RNA STABILITY; RNA STRUCTURE; STRUCTURE ANALYSIS; WILD TYPE;

3' UNTRANSLATED REGIONS; CELL LINE, TUMOR; COLORECTAL NEOPLASMS; GENE DELETION; GENE EXPRESSION REGULATION, NEOPLASTIC; GREEN FLUORESCENT PROTEINS; HUMANS; MICROSATELLITE INSTABILITY; NUCLEIC ACID CONFORMATION; RNA STABILITY; RNA, MESSENGER; RNA, NEOPLASM; TUMOR SUPPRESSOR PROTEINS;

EID: 34547563245     PISSN: 00396060     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.surg.2007.04.002     Document Type: Article

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