Are we undertreating rectal cancer in the elderly? An epidemiologic study

Annals of Surgery

Volumn 246, Issue 2, 2007, Pages 215-221

  Chang, George J ^a   Skibber, John M ^a   Feig, Barry W ^a   Rodriguez Bigas, Miguel ^a  

^a UNIVERSITY OF TEXAS   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ADULT; AGE DISTRIBUTION; AGED; ARTICLE; CANCER CLASSIFICATION; CANCER EPIDEMIOLOGY; CANCER MORTALITY; CANCER PATIENT; CANCER RADIOTHERAPY; CANCER SURGERY; CANCER SURVIVAL; CONFIDENCE INTERVAL; CONTROLLED STUDY; EXCISION; FEMALE; GERIATRIC CARE; HEALTH CARE UTILIZATION; HUMAN; LYMPH NODE METASTASIS; MAJOR CLINICAL STUDY; MALE; MULTIVARIATE LOGISTIC REGRESSION ANALYSIS; PRIORITY JOURNAL; RECTUM CARCINOMA; RECTUM RESECTION; RISK ASSESSMENT; SEX DIFFERENCE; SURGICAL TECHNIQUE; TREATMENT OUTCOME; UNIVARIATE ANALYSIS;

ADENOCARCINOMA; AGE FACTORS; AGED; COLECTOMY; FEMALE; FOLLOW-UP STUDIES; HUMANS; INCIDENCE; MALE; MIDDLE AGED; MULTIVARIATE ANALYSIS; NEOPLASM STAGING; PROGNOSIS; RECTAL NEOPLASMS; RETROSPECTIVE STUDIES; SEER PROGRAM; SURVIVAL RATE; UNITED STATES;

EID: 34547562063     PISSN: 00034932     EISSN: None     Source Type: Journal    
DOI: 10.1097/SLA.0b013e318070838f     Document Type: Article

References (25)

1. Jemal A, Siegel R, Ward E, et al. Cancer statistics, 2006. CA Cancer J Clin. 2006;56:106-130.
2. Colorectal Cancer Collaborative Group. Surgery for colorectal cancer in elderly patients: a systematic review. Lancet. 2000;356:968-974.
3. Clark AJ, Stockton D, Elder A, et al. Assessment of outcomes after colorectal cancer resection in the elderly as a rationale for screening and early detection. Br J Surg. 2004;91:1345-1351.
4. Fietkau R, Zettl H, Klocking S, et al. Incidence, therapy and prognosis of colorectal cancer in different age groups: a population-based cohort study of the Rostock Cancer Registry. Strahlenther Onkol. 2004;180:478-487.
5. Vercelli M, Capocaccia R, Quaglia A, et al. Relative survival in elderly European cancer patients: evidence for health care inequalities. The EUROCARE Working Group. Crit Rev Oncol Hematol. 2000;35:161-179.
6. Iversen LH, Pedersen L, Riis A, et al. Age and colorectal cancer with focus on the elderly: trends in relative survival and initial treatment from a Danish population-based study. Dis Colon Rectum. 2005;48:1755-1763.
7. Townsley C, Pond GR, Peloza B, et al. Analysis of treatment practices for elderly cancer patients in Ontario, Canada. J Clin Oncol. 2005;23:3802-3810.
8. Mellgren A, Sirivongs P, Rothenberger DA, et al. Is local excision adequate therapy for early rectal cancer? Dis Colon Rectum. 2000;43:1064-1071; discussion 1071-1074.
9. National Cancer Institute D, Surveillance Research Program, Cancer Statistics Branch. Surveillance, Epidemiology, and End Results (SEER) Program (www.seer.cancer.gov) Public-Use Data (1973-2002), released April 2005, based on the November 2004 submission.
10. NIH Consensus Conference. Adjuvant therapy for patients with colon and rectal cancer. JAMA. 1990;264:1444-1450.
11. Young JL, Roffers SD, Ries LAG, et al. SEER Summary Staging Manual-2000: Codes and Coding Instructions [NIH Publication No. 01-4969]. Bethesda, MD: National Cancer Institute; 2001.
12. Engstrom PF, Benson AB 3rd, Chen YJ, et al. Rectal cancer clinical practice guidelines in oncology. J Natl Compr Canc Netw. 2005;3:492-508.
13. Paty PB, Nash GM, Baron P, et al. Long-term results of local excision for rectal cancer. Ann Surg. 2002;236:522-529; discussion 529-530.
14. Garcia-Aguilar J, Mellgren A, Sirivongs P, et al. Local excision of rectal cancer without adjuvant therapy: a word of caution. Ann Surg. 2000;231:345-351.
15. O'Connell JB, Maggard MA, Ko CY. Cancer-directed surgery for localized disease: decreased use in the elderly. Ann Surg Oncol. 2004;11:962-969.
16. Lemmens VE, Janssen-Heijnen ML, Verheij CD, et al. Co-morbidity leads to altered treatment and worse survival of elderly patients with colorectal cancer. Br J Surg. 2005;92:615-623.
17. Schrag D, Cramer LD, Bach PB, et al. Age and adjuvant chemotherapy use after surgery for stage III colon cancer. J Natl Cancer Inst. 2001;93:850-857.
18. Limpert P, Longo WE, Kelemen PR, et al. Colon and rectal cancer in the elderly: high incidence of asymptomatic disease, less surgical emergencies, and a favorable short-term outcome. Crit Rev Oncol Hematol. 2003;48:159-163.
19. Abir F, Alva S, Longo WE. The management of rectal cancer in the elderly. Surg Oncol. 2004;13:223-234.
20. Au HJ, Mulder KE, Fields AL. Systematic review of management of colorectal cancer in elderly patients. Clin Colorectal Cancer. 2003;3:165-171.
21. Puig-La Calle J Jr, Quayle J, Thaler HT, et al. Favorable short-term and long-term outcome after elective radical rectal cancer resection in patients 75 years of age or older. Dis Colon Rectum. 2000;43:1704-1709.
22. Smith JJ, Lee J, Burke C, et al. Major colorectal cancer resection should not be denied to the elderly. Eur J Surg Oncol. 2002;28:661-666.
23. Barrier A, Ferro L, Houry S, et al. Rectal cancer surgery in patients more than 80 years of age. Am J Surg. 2003;185:54-57.
24. Sargent DJ, Goldberg RM, Jacobson SD, et al. A pooled analysis of adjuvant chemotherapy for resected colon cancer in elderly patients. N Engl J Med. 2001;345:1091-1097.
25. Goldberg R, Sargent D, Bleiberg A, et al. A pooled safety and efficacy analysis of the FOLFOX4 regimen (bi-monthly oxaliplatin plus fluorouracil/leucovorin) in elderly compared to younger patients with colorectal cancer. ASCO Gastrointestinal Cancers Symposium, San Francisco, CA, 2006.