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Volumn 17, Issue 17, 2007, Pages 4812-4818
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Novel inhibitor for fibroblast growth factor receptor tyrosine kinase
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Author keywords
Antiangiogenesis; Antiproliferation; Binding mode; Docking; FGFR1; FGFR1 inhibitor; Phenyl indolin 2 one; SU6668
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Indexed keywords
2,4 DIMETHYL 5 (2 OXO 1H INDOL 3 YLMETHYLENE) 3 PYRROLEPROPIONIC ACID;
3 [4 METHYL 2 (2 OXO 3 INDOLINYLMETHYLIDENYL) 3 PYRROLYL]PROPIONIC ACID;
6 DIMETHOXY PHENYL INDOLIN 2 ONE;
FIBROBLAST GROWTH FACTOR RECEPTOR;
FIBROBLAST GROWTH FACTOR RECEPTOR 1;
INDOLE DERIVATIVE;
MITOGEN ACTIVATED PROTEIN KINASE;
NP 603;
PD 173074;
PROTEIN TYROSINE KINASE;
RECEPTOR BLOCKING AGENT;
SEMAXANIB;
STRESS ACTIVATED PROTEIN KINASE;
SU 4984;
UNCLASSIFIED DRUG;
ARTICLE;
BINDING AFFINITY;
CELL PROLIFERATION;
CRYSTAL STRUCTURE;
DRUG POTENCY;
DRUG SYNTHESIS;
ENZYME INHIBITION;
HUMAN;
LIGAND BINDING;
PROTEIN BINDING;
PROTEIN PHOSPHORYLATION;
RECEPTOR BINDING;
STRUCTURE ACTIVITY RELATION;
SUBSTITUTION REACTION;
WESTERN BLOTTING;
CHEMISTRY, PHARMACEUTICAL;
CRYSTALLOGRAPHY, X-RAY;
DOSE-RESPONSE RELATIONSHIP, DRUG;
DRUG DESIGN;
ENZYME INHIBITORS;
FIBROBLAST GROWTH FACTOR 1;
HUMANS;
HYDROGEN BONDING;
INDOLES;
JNK MITOGEN-ACTIVATED PROTEIN KINASES;
LYSINE;
MODELS, CHEMICAL;
MOLECULAR CONFORMATION;
PYRIMIDINES;
PYRROLES;
RECEPTOR, FIBROBLAST GROWTH FACTOR, TYPE 1;
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EID: 34547498439
PISSN: 0960894X
EISSN: None
Source Type: Journal
DOI: 10.1016/j.bmcl.2007.06.058 Document Type: Article |
Times cited : (28)
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References (13)
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