Sulfenamides as prodrugs of NH-acidic compounds: A new prodrug option for the amide bond

Bioorganic and Medicinal Chemistry Letters

Volumn 17, Issue 17, 2007, Pages 4910-4913

  Guarino, Victor R ^a   Karunaratne, Veranja ^a   Stella, Valentino J ^a  

^a UNIVERSITY OF KANSAS   (United States)

Author keywords

Amide; Bioavailability; Dissolution rate; NH acid; Permeability; Prodrug; Solubility; Stability; Sulfenamide

Indexed keywords

AMIDE; BENZAMIDE; CARBAMAZEPINE; CARBAMIC ACID DERIVATIVE; LINEZOLID; SULFENAMIDE DERIVATIVE; SULFUR; UREA DERIVATIVE;

ACIDITY; ARTICLE; ATOM; DRUG DESIGN; DRUG SYNTHESIS; HYDROPHILICITY; LIPOPHILICITY; PHYSICAL CHEMISTRY;

AMIDES; AMINES; CHEMISTRY; CHEMISTRY, PHARMACEUTICAL; DRUG DESIGN; HYDROGEN-ION CONCENTRATION; HYDROLYSIS; KINETICS; MODELS, CHEMICAL; PRODRUGS; SULFUR; TEMPERATURE;

EID: 34547494231     PISSN: 0960894X     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.bmcl.2007.06.037     Document Type: Article

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